绝经

All the compressed centrums depicted even lower attenuation with papery cortical bone and notable sparse trabeculae;Where as,the fracture line was not found in all compressed centrums.

对X线诊断、临床证实的30例绝经后脊柱原发性骨质疏松患者椎体压缩的CT表现进行回顾性分析。

DATA SELECTION: Literatures about the comparison of bone density and bone metabolic change between inhaled GC group and control group were consorted deleting randomized controlled trial so as to look up the whole content of healthy controls;While patients in the treatment group received GC inhalation.

研究对象为服用糖皮质激素的成年男性和绝经前女性哮喘患者。资料选择：选取试验包括吸入糖皮质激素治疗组和对照组的骨密度、骨代谢变化比较的相关文献，进行初审，删除明显不随机临床试验的研究，然后查找余下的文献全文，进一步判断是否为 RCT。纳入标准：① RCT，无论是否为单盲、双盲或非盲法；②平行对照组，即未使用激素的哮喘患者或健康对照；治疗组为吸入激素的哮喘患者。

Results 67 cases were hysteromyoma,28 cases were endometrial bleeding of post-menopause,11 cases were thickening of endometria,36 cases were mass of appendix,15 cases were mass-like strong echo in the cavity of uterus.

结果 子宫肌瘤67例，绝经后子宫内膜出血28例，子宫内膜厚度11例，附件包块36例，宫腔内团状稍强回声15例。

Objective: This experimental study is based on earlier animal and clinical experiment, drawn thinkings of combinations with two methods and pursued a synthesis method of high-efficiency, cheap and convenient calcium and exercise treatment. We adopt taking natural-clam's casing powder and preconcereted-intensity excises to intervene shape of osteoporosis in gelded rats, than we compare the indexes such as the biomechanics indexes of the right femur and the third lumbar vertebrae, the weight and uterus quotiety of rats before the experiment to these indexes after the experiment. We hope to find better and suitable way to prevent and treat the postmenopausal osteoporosis and offer reference for clinic.

目的 本实验的主要目的是在前期动物实验的基础上，引入两种方式联合干预的思维，立足于探求既高效又经济、方便的补钙剂加上与运动疗法相联合的方式，对切除雌性大鼠卵巢而复制成的骨质疏松症模型进行服用天然贝类蛤蜊壳粉，同时施以预定强度的运动刺激的方法，再通过试验前后大鼠体重、子宫指数的变化及大鼠股骨和椎体生物力学指标的对比变化进行分析，以期探索出防治绝经后骨质疏松症的更好的、更适宜于大众的手段；并为天然钙剂和运动联合作用防治PMOP提供参考。

All patients were postmenopausal (median age 61.0 y; range, 45-76). Squamous cell hyperplasia was identified in 1 case and lichen sclerosus in 1 case. The invasive squamous cell carcinoma was of keratinizing type in 3 cases and basaloid in 1 case.

这4名患者均为绝经后女性（中位年龄61.0岁，范围：45-76岁）。1名患者确认有鳞状细胞增生，其他3名有硬化性苔藓。3名患者的浸润性鳞状细胞癌为角化型，另一名为基底细胞样。

It is one of the key pathogeneses of postmenapausal osteoporosis that estrogen deficiency leads to the decrease of OPG、TGFβ expression and the increasing expression of some bone-resorbing cytokines as OPGL、M-CSF and TRAIL, then stimulates osteoclast differentiation and activity, which potentiates bone resorption and bone loss:(2) ICI182780 shows partial transactivating function in osteoblasts, so it should belong to a kind of selective estrogen receptor modulators .

雌激素缺乏可能导致HOB中OPG、TGFβ的表达减少，而解除了对OPGL、M-CSF和TRAIL等刺激OC生成和活化的细胞因子的抑制作用，OC的数量和活性增加，导致骨吸收增强和骨量丢失，这是导致绝经后骨质疏松症的一个重要的发病机制；ICI182780在成骨细胞内表现出促转录活性，因此它并非纯ER拮抗剂，而应属于选择性雌激素受体调节剂(selective estrogen receptor modulator，SERM)。

Clinical study of a Chinese medicine of replenishing kidney in treating postmenopausal osteoporosis .

补肾中药在治疗绝经后骨质疏松的临床研究。

The program of AER+RES was similar to AER, but went through resistance exercise 20min in base section of every exercise trail.Result: Prior to intervention, adiponectin levels were significantly correlated with BMI、 WHR、 COS、 LN、 LN、 TG、 LG10、 LN、 weight、 waist、 FM、%F, and leptin levels were significantly correlated with BMI、 WHR 、 LN 、 LN 、 TG 、 HDL-C 、 LG10、 apoB 、 apoA1/apoB、 waist、 F1M、%F. Stepwise multiple regression analysis revealed that LG10; COS and waist was an predictor of basal adiponectin levels , and %F,apoB and WHR was an predictor of basal leptin levels. In early obesity, adiponectin and leptin can be worsened , along with the changed of body component, fasting plasm glucose and lipid accumulation. After intervention, both group were significantly reduction in FM,%F,weight, WHR,FPG and TG, while HDL-C had significantly increased.AER exhibited significant in leptin, while AER+RES did not show the change. Insulin and HOMA-IR were changed in both groups. The control group exhibited no significant change in any variables. Although adiponectin levels were unchanged in the three groups, a significant negativecorrelation between delta %F, delta WHR and delta FPG was observed. Futhermore, if compare the degree of delta weight, we fought a significant increased in adiponectin between the group of delta weight higher (=3kg) than delta weight lower(=0kg), delta %F, delta WHR and delta weight were significant negative correlation with delta leptin.

结果：绝经妇女脂联素水平与体重指数、腰臀比、空腹血糖、空腹胰岛素、LEP、TG、极低密度脂蛋白胆固醇、胰岛素抵抗指数、体重、腰围、体脂含量、体脂百分比显著相关；瘦素水平与BMI、WHR、FINS、LEP、TG、HDL-C、VLDL-C、载脂蛋白B、apoA1／apoB、腰围、FM、％F等指标显著相关；多元逐步回归分析显示LG10、COS和腰围是基线脂联素水平的预测变量，而％F，apoB和WHR是基线瘦素水平的预测变量；在肥胖前期，脂联素、瘦素已经出现明显不良变化，同时也伴随着体成分、空腹血糖和血脂的异常；运动实验后，两个运动组的FM、％F、体重、WHR、FPG、TG都显著下降，而HDL-C显著上升；AER组瘦素显著下降，而AER+RES组则没有显著变化；两组的胰岛素和HOMA-IR水平都有显著下降；对照组所有指标都没有明显变化；尽管运动后脂联素水平没有显著变化，但是脂联素变化量与％F、WHR和血糖变化量显著负相关，而且如果按照运动后体重下降的程度比较，则体重下降大(≥3kg)的受试者比下降小的(≤0kg)脂联素水平有明显升高；运动后瘦素水平的变化量与％F，WHR及体重的变化量显著负相关。

Objective To explore the distribution and difference of TGF-β_1 in postmenopausal women with normal blood pressure and with hypertension.

目的：探讨绝经后女性高血压组和正常血压组之间转化生长因子β1的分布及两组之间有无区别。

Postmenopausal women who want to decrease their risk of colds would be well advised to dust off their sneakers and get moving, suggests a new study led by researchers at Fred Hutchinson Cancer Research Center.

绝经后的妇女要减少他们的风险，感冒会好宜灰尘，他们的运动鞋和动，提出了一种新的实验，由研究人员在Fred Hutchinson癌症研究中心。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐