给药

The Xiaojingtong antiinflammatory effect was demonstrated in rats using inflammatory models including auricle edema induced by xylene in mice,and paw edema induced by carrageenin.

结果复方消经痛胶囊2.0，1.0 g/kg可明显减少醋酸所致疼痛模型小鼠的扭体次数（P＜0.05）。2.0 g/kg在给药后90 min可明显提高热板致小鼠疼痛阈值， 1.0，0.5 g/kg组则在给药后120 min痛阈值明显提高（P＜0.05）。

BACKGROUND: The chronobiology of asthma suggests that, for once-daily dosing, an evening dose may be the most effective treatment paradigm.

背景：对哮喘的时间生物学研究表明，在每日给药1次的前提下，夜间给药可能是最佳的治疗模式。

60Rgan coefficient: Compared with normal group, the kidney organ coefficient of 1-hour group risen obviously.

草乌给药30天观察：(1)足肿胀度：各给药组右足肿胀度较模型对照组有不同程度的减轻。

The scores of stereotyped behavior gradually increased concomitantly with the time of administration.

MK-801和KET各剂量组在连续给药8d时间内小鼠定型行为的得分随给药时间的延长均有所升高。

Observing the effects of DS on acetic acid-induced writhing and increased capillary permeability in mice when it was administered intraperitoneally, the granuloma formation induced by cotton pellet in rat when it was applied locally, and the mucous membrane irritation of DS lozenge.

观察双氯芬酸钠低剂量低浓度腹腔给药对醋酸致小鼠扭体作用及毛细血管通透性增加的影响，局部给药对大鼠棉球肉芽形成的影响，局部长时间接触对的刺激作用。

The affected chicks acquired the morphine conditioned place preference more quickly, and maintained it much longer. Experiment 3 showed that during E5-8, injecting delta receptor antagonist naltrindole reversed the learning and memory impairment caused by morphine while delta receptor agonist DPDPE impaired learning and partial memory function. On the other hand, mu opioid receptors had little effect. As for E17-20, given naloxonazine can reverse the increases of susceptibility to morphine, and the mu receptor agonist DAGO cause the increases of susceptibility to morphine. Delta receptors have no effect.

研究结果发现：经过对鸡胚发育不同时间段的吗啡给药，胚胎期发育E5-8阶段给予吗啡的小鸡学习记忆受损最为严重，表现为学习和记忆功能的严重下降；而E17-20时段吗啡给药的小鸡更容易获得吗啡CPP且保持时间更长。E5-8阶段给予delta受体拮抗剂natrindole能够翻转吗啡对学习和记忆的损害作用，并且给予delta受体激动剂DPDPE也损害学习和部分记忆功能，mu受体作用不大。E17-20阶段拮抗mu受体能够抑制成瘾易感性的增加，激动mu受体可以增加小鸡的成瘾易感性，delta受体没有明显作用。

In the present study, the new sensitive and specific LC/MS/MS method was developed for the simultaneous determination of magnesium lithospermate B, rosmarinic acid and lithospermic acid and their major metabolites in biological samples. The pharmacokinetics of S. miltiorrhiza depside salts in dogs, rats, and humans conducted the developed LC/MS/MS method, and they would be useful for new drug development and design.

在此基础上，系统研究了创新中药丹参多酚酸盐多个成分在Beagle犬及大鼠体内的药物代谢动力学特征，包括多剂量、多种给药方式的影响，及吸收、分布、代谢、排泄特征；同时进行人体药物代谢动力学研究，为设计合理给药方案和临床安全有效用药提供了理论依据，对传统中药的现代化研究具有显著的示范作用。

The effect of Jiusuyu on ebriety rate, ebriety time of acute alcoholism mice observed after preventing treatment 80 healthy mice, bisexual and each half, were randomly divided into 4 groups, 20 mice every group, namely model group (equal volume physiological saline were given through the means of watering stomach), low-dose group of Jiusuyu (called low-dose group, 1.62g/100g avoirdupois Jiusuyu drank through the means of watering stomach), high-dose group of Jiusuyu (called high-dose group, 3.24g/100g avoirdupois Jiusuyu drank through the means of watering stomach), and Gehuaji-echeng liquid control group (called control group, 1.31g/100g avoirdupois) Gehuajiecheng liquid were drunk through the mea

酒速愈预防性给药对急性酒精中毒小鼠醉酒时间、醉酒率的影响健康昆明种小鼠，雌雄各半，随机分为4组：模型组、酒速愈低剂量组(灌服酒速愈1.62g生药/100g体重)、酒速愈高剂量组(灌服酒速愈3.24g生药/100g体重)、葛花解酲汤组(灌服葛花解酲汤1.31g生药/100g体重)，每组20只。各组小鼠禁食12hs，各治疗组均一次性给药，模型组灌服生理盐水，30mins后均以56°红星二锅头酒灌胃(1.4ml/100g体重)。观察记录小鼠醉酒时间(从清醒到翻正反射消失的时间)，小鼠醉酒与否以翻正反射是否消失为标准：小鼠灌酒后将其背向下轻轻放入鼠笼，若小鼠背

Methods All the organophosphate poisoning patients who were treated by Beijing Emergency Medical Center from 2001 to 2004 were divided into control group and treatment group. The treatment group was given continuous micro pumping treatment besides the atropine and 2-PAM intravenous transfusion treatment.

将北京急救中心2001-2004年所救治的52例重度有机磷农药中毒患者分为治疗组和对照组，治疗组采用阿托品与碘解磷定先静脉注射后持续微量泵静脉维持给药方法，对照组采用传统间歇给药方法。

Results: 48 h after treatment, most of the patients had a marked improvement in irf and ret (p＜0.05), and irf showed a more significant increase. moreover, the value before treatment and 48 h after treatment of irf had no overlap; irf and ret were further increased after 1 week; after 12 weeks irf%, hct, ret, rbc and hb were significantly increased than before treatment, bone marrow erythrocytic series proliferation was more active than that before treatment, each kind of erythroblast ratio and the percentage of total erythrocytic series were significantly increased, especially late erythroblasts proliferation.

结果：治疗过程中大部分患者在epo注射48 h后irf、ret升高（p.05），irf升高更为显著，且irf在给药前和给药48 h后的数值无重叠区，1周后irf、ret进一步升高，12周时irf、hct、ret、rbc、hb均比用药前显著增高，骨髓红系增生较治疗前明显活跃，各类幼红细胞比率及总红系所占百分数均显著升高，其中以晚幼红细胞增生最为明显。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了