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Objective To compare the difference in bioavailability of microemulsion and pill by detecting the concentration of andrographolide in rabbit plasma.

目的 通过检测给药后家兔血浆中穿心莲内酯的含量,比较微乳制剂与片剂的生物利用度的差异。

The application of midazolam is effective on anti-axiety, sedation and anterograde amnesia in orthopaedic surgery with epidural block and the dose of 0.075mgkg^(-1) is more effective and safe.

咪唑安定应用于硬膜外麻醉下行骨科手术的抗焦虑、镇静及顺行遗忘效果好,按0.075mgkg^(-1)给药效果满意且安全性高,不良反应少。

Result: Peppermint oil 120、60、30 mg/kg giving into duodenum could significantly increase the secretion volume of bile in rat, and slightly increase the concentration of cholic acid in bile. Peppermint oil 5, 0.5 and 0.05mg/L has no dissolving effect on cholesterol gallstone and bile pigment gallstone in 4~5 weeks.

结果:薄荷油120、60、30mg/kg十二指肠给药,对大鼠有明显的利胆作用,并能轻度增加胆汁中胆汁酸的排出量。5、0.5、0.05mg/L在4~5周内对胆固醇结石、胆色素结石无明显溶解作用。

The Change of temperature before and after the modal-making and administration, the content of plasma cAMP, quotient of cAMP and cGMP and the peripheral blood picture was examined to study the fever-preducing function of Dihuang on RFEHYDS.

通过测定造模、给药前后体温、血浆cAMP含量、cAMP/cGMP比值以及外周血象的变化,研究地黄对家兔阴虚热盛证型发热的解热作用。

The blood glucose levels in many strain animal models were determined after oral administration, with the models of diabetes induced by alloxan, of hyperglycemic mice induced by epinephrine and glucose, and normal mice.

采用四氧嘧啶所致糖尿病模型、肾上腺素和葡萄糖引起的高血糖小鼠模型,以及正常小鼠口服给药,测定各模型小鼠的血糖水平;并对GXTF进行了急性毒性试验。

Methods Whole cell patch clamp technique was used to study the changes of voltage dependent calcium current of 22 neurons in caudate nucleus before and after morphine treatment.

采用膜片钳全细胞记录模式观察了 2 2例尾核神经元电压门控性钙通道在吗啡给药前后的电流变化。

Methods Forty cases of vigil coma were selected and divided randomly into the therapeutic group(20 cases)and the control group (20 cases).

方法选用符合醒状昏迷条件的患者40例,随机分为治疗组(20例)及对照组(20例),治疗组用美多巴及溴隐亭治疗,对照组用安慰剂同法给药

Following consecutive drug administration for 7 days, the rats were submitted to behavior detection using diving platform and water maze experiments to compare the degree of dementia in rats.

连续给药7 d后,采用跳台实验和水迷宫实验对大鼠进行行为学检测,比较大鼠痴呆程度。

The results indicate that both the on/off of release of ATP and the amount of released ATP can be controlled by applying appropriate potential on the electrode.

通过控制不同的电位可以控制释放的时间及释放量的多少。这种电极在研究神经组织的活动和改变传统的给药方式方面有很重要的意义。

ResultsIn total,94% were reported by pharmaceutists,78% were associated with anti-infaction drugs,85% were administered by intravenous drip.The most common displays of ADRs were the lesion of skin and the appendants,followed by the lesion of digestive system.

结果94%是由药师报告的;78%的不良反应是由抗感染药物引起的;85%的不良反应是通过静脉滴注给药的;ADR的临床表现以皮肤及其附件最多,其次是消化系统的反应。

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The split between the two groups can hardly be papered over.

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This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

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