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Shen tonics and nourishing Yin were selected, and decided into the groups of liquid of complex prescription by the Yin-Yang principles of the treatment: IQ and NY group, YT and NY group, ST and NY group and so on, which were respectively boiled, administrated the rats via gavage and separated the sera of drugs for preparation, the sera were served in HCSMMC-7721 in vitro, normal sera of rats and Retin acid as matched controls, MTT colorimetric method was applied to assay cell proliferation.

选取临床肝癌治疗常用的益气、温阳、补肾、养阴等扶正治法的代表药物,并根据阴阳治则理论将其分别配伍为益气养阴、温阳养阴及补肾养阴等治法的小复方,分别煎成汤液,采取大鼠灌胃给药后分离药物血清的方法制备药物血清,作用于体外培养的SMMC-7721人肝癌细胞,以正常大鼠血清和维甲酸作对照。

In one preferred embodiment, the applicator is a once usable tube containing a single dosage of formulation, and has an aperture, preferably equipped with a rupturable removable cap, provided at the distal end thereof, i.e. the end to be disposed adjacent to the patient's cervix on full and proper insertion into the vagina.

在一个较优的实施例中,该给药器为一个含有单次剂量药物的一次性塑料管,末端(即完全、恰当地插入阴道后,毗邻患者宫颈的那一端)有一个孔眼,在孔眼上安装一个可断开除去的盖帽更佳。

The bcl-2/bax of Safflor group treated before ICH 24 hours ahead,after ICH 0 hour were lower than that of Safflor group treated after ICH 6,12 or 24 hours. When the treated group were injected Safflor after ICH 6,12,24 hours,The number of caspase-3 positive cell around

在不同时间给予红花注射液治疗脑出血大鼠,均能不同程度地促进脑出血大鼠神经功能的恢复,其中术后6h给药组治疗效果最好,其可能通过促进Bcl-2蛋白的表达,抑制Bax和Caspase-3蛋白的表达,从而抑制血肿周围的细胞凋亡。

When the treated group were injected Safflor after ICH 6,12,24 hours,The number of caspase-3 positive cell around hematoma was gradually increased and the number of bcl-2/bax positive cell was gradually degraded and the number of TUNEL positive cell of Safflor group treated after ICH 6 hours were less than that of Safflor group treated after ICH 24 hours.

在不同时间给予红花注射液治疗脑出血大鼠,均能不同程度地促进脑出血大鼠神经功能的恢复,其中术后6h给药组治疗效果最好,其可能通过促进Bcl-2蛋白的表达,抑制Bax和Caspase-3蛋白的表达,从而抑制血肿周围的细胞凋亡。

Results Compared with ICH model group,Safflor injection could significantly alleviate neurological system damage symptoms,heighten the ratio of bcl-2/bax,and reduce the number of caspase-3 positive cell and the number of TUNEL posit

在不同时间给予红花注射液治疗脑出血大鼠,均能不同程度地促进脑出血大鼠神经功能的恢复,其中术后6h给药组治疗效果最好,其可能通过促进Bcl-2蛋白的表达,抑制Bax和Caspase-3蛋白的表达,从而抑制血肿周围的细胞凋亡。

There were fewer positive cells in other groups. The change tendency from few to many is control 2, MP3→MP2, MP4→control 1, MP1 Conclusions 1. Methylprednisolone is a very potential anti-scar drug and can elevate successful rate of rabbit filtration. 2. Used in the way of cotton patch, MP has lower ocular toxicity. Samely, high concentration could be got topically. 3. In definite range, the activity of MP is concentration-dependent. In other words, the activity can be promoted with the increase of concentration. Total results considered, 100mg/ml MP group is identified to have the best effect of all MP groups in the experiment.

; 实3组与对2组脯间差异不显著(Pl.05),但与其它继间差异显著①<0.05);实2组和实4组间差异不显著,但与其它各组间差异显著(P<0.05人结论1、甲基强的松龙是—种很有潜力的低毒的摊痕抑制剂,可提高兔B湖过阶术的成功率;人甲基强的松溉用术中湿片贴敷的方式,既减轻了毒副作用,又可以达到局部用药的高浓度,是一种值得推荐的给药方法;3、在一定范围内,甲强龙的作用与浓度呈正相关关系,本次实验以 100ined组效果最好。

Objective: A HPLC-ECD method was established to determine scutellarin in rat bile.

中文摘要:目的:建立大鼠胆汁中灯盏花乙素的高效液相-电化学色谱测定方法,研究灌胃给药灯盏花乙素苷元200 mg·kg-1后,代谢产物在胆汁中的排泄方式。

Research on promoting elimination rate of 3-amino-2-oxazolidinone and semicarbazide in turbot Scophthatmus maximus which exposed to bromogeramine and Chinese herbs have been carried out.

采用投喂药饵的给药方式,研究了苯扎溴胺和芳草中药对加速大菱鲆体内呋喃唑酮和呋喃西林代谢物3-氨基-2-恶唑烷基酮(3-am ino-2-oxazolid inone, AOZ)和氨基脲(Sem icarbazide, SEM)消除的作用。

Methods 24 SD rats were randomly divided into normal group,model group,aminophylline treatment group(35 mg/kg), 8 rats in each group. The bronchial asthma model in rats was built by egg protein sensibilization and longterm inhalation provocation. The rats in treatment group were lavaged each day from the first time of provocation.After 4week treatment, the rats were killed to obtain lung tissue for staining with HE.

24只SD大鼠随机分为正常组、模型组、治疗组,每组8只,除正常组外以卵蛋白致敏并吸入激发法制备大鼠哮喘模型,治疗组、模型组从第1次哮喘激发开始(造模第3周)分别给予氨茶碱、0.9%氯化钠溶液灌胃给药,1次/d,用药4周处死大鼠,取肺组织HE染色,用彩色图像分析仪测量支气管壁面积、支气管平滑肌面积,用ELISA双抗体夹心法测定肺组织MMP9和TIMP1含量。

Objective and Methods To evaluate mechanisms of drugs commonly used in the treatment of septicemia, giving antibiotics including Minocycline (10 mg/kg), Clindamycin (10 mg/kg), Cyclosporin (15 mg/kg) and Platonin (10 mg/kg) to septicemic rat injected with LPS. Clinical improvement, blood pressure, heart rate, survival time are assessed, and the amount of endogenous NO production is determined.

本实验之目的是要探讨在临床上常用於治疗败血症的数种药物,可能的作用机转;藉由注射老鼠LPS模拟败血症前,先给予Minocycline,Clindamycin,Cyclosporin,Platonin等药物治疗,评估药物的改善状况,同时观察血压、心跳、动物存活时间及侦测体内NO的生成量,来比较给药与否之差异,且针对变化的可能原因来探讨。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

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