给药

It was shown that treatment with CS-SH injection could significantly improve the symptoms of OA which was assessed by Mankin grade.

给药5周后取材，做光镜观察Mankin评分、观察关节软骨变化情况。

Methods The experimental mouse was injected with high, middle, and low dosages of marasmius androsaceus po1ysaccharide 5, 10, 20 mg kg^(-1d^(-1) in the abdomen, and the comparison group was given the same volume of saline water i. p. once a day. After treatment for 14 consecutive days, the blood cell count instrument was used to measure the mice hemogram, the phagocytic function of peritoneal macrophage and the ability of carbon granular clearance were observed., the ability of the spleen lymphocytes proliferation was tested by MTT, and the hemolysin production test was used to evaluate the influence of MA polysaccharide on specific humoral immunity in mice.

小鼠腹腔注射不同剂量的鬼毛针多糖5， 10， 20 mgkg^(-1d^(-1)，对照组给予等量生理盐水，每天给药1次，连续14d后，用血细胞计数仪检测小鼠血象；用腹腔巨噬细胞吞噬鸡红细胞实验、碳粒廓清实验观察小鼠吞噬细胞的吞噬能力；采用MTT法测定小鼠脾T淋巴细胞增殖能力；采用血清溶血素形成实验观察鬼毛针多糖对小鼠特异性体液免疫功能的影响。

At the end of experiment, blood was taken from the ear edge vein for measuration of the activity of superoxide dismutase and concentration of molondialdehyde, nitric oxide and endothelin.

将实验兔24只随机分为三组，正常组、模型组、四逆汤组，造模方法同四逆汤抗实验性AS的作用研究，四逆汤组给药剂量同四逆汤抗实验性AS作用的低剂量。

Objective Basing on series of prophase research on premenstrual syndrome with invasion of the hyperactive liver-qi, Random double-blind and double simulation and control method were adopted in this study. The study used tables as Daily Record of Severity of Problems and symptoms score form to evaluate the efficacy of jingqianping granule for treatment of PMS with invasion of the hyperactive liver-qi objectively. Endocrine and neurotransmitters were detected to explore the medicative mechanism of Chinese medicine on PMS. Methods All cases were from the staff of the first Affiliated Hospital, Guangzhou University of TCM.

目的本研究在经前期综合征肝气逆证前期一系列研究的基础上，采用随机双盲对照的给药方法，借助《PMS症状程度打分表》、《月经周期症状每日自我评价表》和《症状严重程度每日记录量表》等量表客观评价具有平肝理气功能的中药新药&经前平颗粒&对经前期综合征肝气逆证的临床疗效，并检测患者治疗前后内分泌激素和神经递质变化，以客观评价中医药治疗经前期综合征肝气逆证的疗效，探讨中医药对经前期综合征治疗的机理。

Results Free MMC 0.15625～5.0μg/kg significantly increased the positive rate of PCE micronuclear test, the chromosome aberration rate and rat teratogenecity, but the mitomycine C absorbed onto ACNP did not increased these heredity and proliferation toxicological indexes in a dose range of 0.625～10.0μg/kg.

结果 游离丝裂霉素腹腔注射0.15625～2.5μg/kg 均可导致小鼠骨髓微核试验阳性率和CHL染色体畸变率，用纳米活性炭吸附MMC后给药，在0.625～20.0μg/kg 腹腔注射后都没有明显增加微核试验阳性率和染色体畸变率。

Methods since 2004 at my hospital for medical treatment in patients with chronic heart failure 58 cases were randomly divided into two groups, treatment group 32 cases, at the basis of conventional therapy with captopril and add 5-Isosorbide Mononitrate; control group 26 cases, only in the conventional therapy plus captopril; administration of the two groups were observed at 8 weeks of the efficacy and safety.

选取2004年以来在我院治疗的慢性心功能不全患者58例，随机分成两组，治疗组32例，在常规治疗的基础上加用卡托普利和5-单硝酸异山梨醇酯；对照组26例，只在常规治疗的基础上加用卡托普利；观察两组在给药8周的疗效及安全性。

Pretreated with the extract from Morchella esculenta for 16 days,mice modles of acute hepatic injury were established by the treatment of carbon tetrachloride (CCl4).After 24 hours,the protective effects of the extract from Morchella esculenta in acute hepatic injury were observed through determing the activities of alanine aminotransferase,, Maleic Dialdehyde ,and the contents of proteins in serum.

预防给药16d后，采用CCl4复制小鼠急性肝损伤模型，24h后，眼眶取血，测定血清中丙氨酸氨基转移酶、超氧化物歧化酶、丙二醛以及血清蛋白的变化，观察羊肚菌水提物对急性肝损伤的保护作用。

Immunohistochemistrical section: observe the VEGF protein expression in different cells, the positive ratio detected by a morphometrical analysis system was used as the amount of the VEGF protein expression.

免疫组化染色切片：观察不同给药时间股骨头内VEGF的表达情况；高倍视野下（400倍）沿骨小梁表面计数50个成骨细胞中的阳性细胞数，VEGF成骨细胞阳性率=阳性成骨细胞数/50×100％，3次取平均值；计数每个高倍视野软骨细胞中的阳性细胞数，VEGF软骨细胞阳性率=阳性软骨细胞数/软骨细胞总数×100％，5次取平均值。

Methods Marrow cells from NH mouse were harvested and cultured in α-MEM with 10% fetal bovine serum.The appearance of tartrate-resistant acid phosphatase-staining multinuclear cells and formation of bone resorption pits were measured after 3,6,9 and 12 day exposure to various concentrations of 1,25-2D3 in culture. Results 1,25-2D3 (concentration higher than 10-9mol/L) could induce recruitment of OLCs and their bone resorption activity in a dose-dependent manner.

收集NH小鼠骨髓细胞于含10%胎牛血清的α-MEM培养基中行体外培养，设置不同的1，25-2D3浓度组和给药时间组，并于培养第3、6、9、12天观察记录抗酒石酸酸性磷酸酶(tartrate-resistant acid phosphatase，TRAP)阳性多核巨细胞［或破骨细胞样细胞(osteroblast-like cell，OLC)］以及骨磨片上骨吸收陷窝的数目。

Methods Animal models were established on BALB/c nude mice with subcutaneously transplanted neoplasma of U87 glioma.

建立BALB/c裸鼠U87胶质瘤移植瘤模型，将荷瘤裸鼠随机分为2组，采用间质内注射给药方法。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新