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It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of normal mice.1.2 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of mice with reserpineMethods:Compared with normal group,model group and YJBH group,mice with reserpine which has given Iridoids composition of Valeriana jatamansi Jones as 71.2mg/kg,35.6mg/kg,17.8mg/kg,8.9mg/kg was detected gastric emptying and small intestinal propulsion after 6 days drug given.

结果:蜘蛛香环烯醚萜35.6mg/kg、17.8mg/kg组能减缓胃排空和小肠推作用(P.05),说明蜘蛛香环烯醚萜对正常小鼠胃肠功能有一定的抑制作用。1.2蜘蛛香环烯醚萜对利血平化小鼠胃肠功能的作用方法:小鼠每日腹腔注射利血平造模,同时灌胃给予蜘蛛香环烯醚萜71.2mg/kg、35.6mg/kg、17.8mg/kg、8.9mg/kg与空白组、模型组和越鞠保和丸组对照,给药6日后测定动物的胃排空率和小肠推进率。

Based on this,We designed a series of experiments to study the treatment and its mechanism of Iridoids composition of Valeriana jatamansi Jones of the IBS animal model.1 Research on Iridoids composition of Valeriana jatamansi Jones in the role of gastrointestinal function.1.1 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of normal miceMethods:Compared with normal group and YJBH group,mice which has given Iridoids composition of Valeriana jatamansi Jones as 71.2mg/kg,35.6mg/kg,17.8mg/kg,8.9mg/kg was detected gastric emptying and small intestinal propulsion after 4 days drug given.Results:Compared with normal group,gastric emptying and small intestinal propulsion in 35.6mg/kg and 17.8mg/kg group was inhibited.

课题通过观察蜘蛛香环烯醚萜对正常及IBS模型动物的胃肠道功能、精神活动的影响,以及蜘蛛香环烯醚萜干预下IBS大鼠结肠、血清、中枢5-HT含量,结肠5-HTR3A受体的mRNA和色氨酸羟化酶(TPH1)的mRNA表达,结肠和血浆中SP和VIP含量以及结肠中肥大细胞分布,探讨蜘蛛香环烯醚萜对腹泻型IBS的治疗作用及其作用机理,为临床治疗IBS提供实验依据。1蜘蛛香环烯醚萜对胃肠功能的作用目的:探讨蜘蛛香环烯醚萜对胃肠功能的影响1.1蜘蛛香环烯醚萜对正常小鼠胃肠功能的作用方法:正常小鼠灌胃给予蜘蛛香环烯醚萜71.2mg/kg、35.6mg/kg、17.8mg/kg、8.9mg/kg与空白组和越鞠保和丸组对照,给药4日后测定动物的胃排空率和小肠推进率。

Results S phase cell percentages of all dose groups of juglone were increased compared with the control group.

结果 胡桃醌各给药组S期细胞百分比均高于对照组,并呈剂量依赖性。

Objective To study the effects of pH on the nasal permeability of ketamine hydrochloride KET?

摘要目的研究pH值对盐酸氯胺酮经离体家兔鼻粘膜渗透性的影响,为经鼻腔给药的处方设计和优化提供依据。

Methods (1)the experiment in body:the knubbly cell S 180 and the cwer cancer knubbly cell H 22 was inoculated in left and front axillary of rats,which were taken medicine in stomach next day.Saline,cyclophosphamide and different dose Fufangshuizhiwan were used re-spectively in negative comparison group,electropositive comparison group and Chinese medicine group for12days.

(1)体内抑瘤实验:取小白鼠左前腋下接种S 180 瘤种和H 22 肝癌瘤种,次日开始灌胃给药,阴性对照组给予生理盐水,阳性对照组给予环磷酰胺,中药组分别给予大、小剂量的复方水蛭丸,连续用药12天。

In a situation of the laryngopharyngeal reflux can be diagnosed, the esophagus and the stomach also suffered the same lesions simultaneously. According to the standards of clinical diagnoses, system can help the physicians to diagnosis the degree of laryngopharyngeal reflux.

而在可以把咽喉胃酸逆流发病情况诊断出来的情形下,其同时在食道及胃也有不同程度损伤之并发症,系统根据医师临床给药标准将并发症种类予以分级,其结果可辅助医师诊断咽喉胃酸逆流的严重程度,且具有临床价值。

Methods: In acute or chronic experiment, all SD rats were randomly divided into three groups which included microthromboembolism group with the injection of 400 μg sodium laurate into the coronary arteries of SD rats, TS group with drinking telmisartan (10 mg/kg), and NS group with NS instead of drinking telmisartan (10 mg/kg), and NS group with NS instead of sodium laurate.

将SPF级SD大鼠冠状动脉注射月桂酸钠400μg后,随机分入微栓组和替米沙坦组(饮水中给药10mgkg^(-1)d^(-1)),对照组则以等量生理盐水替代月桂酸钠。

After treatment, the residues of crystal violet and leuco crystal violet in eel tissues were analysed by HPLC-MS.

结果表明:鳗鲡肌肉组织中结晶紫的最高浓度出现在给药后12h;在整个监测过程中,肌肉组织中结晶紫的含量都较低(0~3.91μg/kg);药浴336h后,结晶紫未检出。

With respect to the external application of antibiotics, such as silver-zinic cream and some kinds of sulfadiazine drugs, long-term use has caused concern of severe kidney toxicity and leucocytopenia. On the other hand, the bacteria with antibiotics-resistance could emerge as a result of using such preparations.

另外对于一些长期难愈的病理性创面,例如对于糖尿病性的溃疡创面,普通药物的深层给药受到很大局限且难以收到良好的效果,而利用细菌活菌本身强有力的繁殖和迁徙能力,就可以在创面的深层和夹缝部位发挥独特的作用,从而在某种程度上,减缓创面的进一步加深和感染的扩散。

To observe the effects of SGDP given through sublingual tablets on hemodynamics and myocardial oxygen consumption in anesthetic dogs which were operated to expose heart, we put the electro-magnetic flowmetre feeler onto the the levo of coronary artery and the root of aorta to measure the the coronary arterial blood flow and cardiac output, left ventricular pressure was observed by the pipe into the left ventricle of the heart.

为观察舒冠滴丸舌下给药对麻醉犬心脏血流动力学及心肌耗氧量的影响,实验采用开胸暴露心脏,于冠状动脉左旋支及主动脉根部放置电磁流量计探头,分别测冠脉血流量和心输出量。左心室插管测左室内压。

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