给药

The Efficacy of Intratracheal Administration of Vecuronium in Rats, Compared with Intravenous and Intramuscular Administration

大鼠气道内给予维库溴胺的效能：和静脉以及肌肉途径给药的比较。

The rats of group T were intratracheally administered rAAV-asIL4 on day 1 and day 14. rAAV-GFP was used as a control. The nucleated cells and eosinophils in bronchoalveolar lavage fluids were counted.

Southern blot法检测合成病毒的滴度。rAAV-asIL4在动物实验开始的第1天和第14天2次通过气道给药干预哮喘大鼠，实验中同时设立大鼠正常组、哮喘组以及rAAV-GFP干预组。

On experimental day （ day 0 ）, the rats were intratracheally instilled with bleomycin （ 5mg.kg -1 .body weight ）,and then treated with Angelica Sinensis 100mg.kg -1 and 200mg.kg -1 until they were killed.

按 BLM 5mg.kg -1 体重复制大鼠肺纤维化模型， 24 小时后给药，于 7 、 14 、 28 天观察肺间质纤维化形成的病理变化和肺匀浆中谷胱甘肽、透明质酸的含量变化。

Intratympanic administration is better than that by stomach intestine or vessel,which can result in high accumulated concentration in endolympha and perilympha by directly entrying inner ear and get out of the way of blood-labyrinth barrier.

鼓室用药优于胃肠或静脉给药，可避开血-迷路屏障直接进入内耳使得内、外淋巴液中的药物浓度较高；同时避免了全身用药的不良反应。

Objective To study the efficacy of intravitreous injection or sub-Tenaninfusion of triamcinolone acetonide for diabetic macular oedema.

目的 观察曲安奈德注射液玻璃体腔注射和Tenon囊下给药治疗糖尿病性黄斑水肿的疗效。

Abstract］ Objective To determine the curative effect of treatment for diabetic macular edema with triamcinolone acetonide combined with laser photocoagulation and to appraise the safety of two different ways to administer triamcinolone acetonide, peribulbar injection and intravitreous injection.

目的 总结曲安奈德(triamcinolone acetonide，TA)联合黄斑部格栅样光凝对糖尿病性黄斑水肿的疗效，评估TA的两种不同给药方式的安全性。

Methods Forty-eight patients (50 eyes) with diffuse diabetic macular edema were randomly divided into two groups: twenty-five eyes were treated with an intravitreous injection of triamcinolone acetonide (4 mg/0.1 ml), and another twenty-five were treated with a peribulbar injection of triamcinolone acetonide (40 mg/1 ml).

将48例（50眼）弥漫性黄斑水肿患者随机分为曲安奈德玻璃体腔（0.1 ml，4 mg）注射目的总结曲安奈德(triamcinolone acetonide，TA)联合黄斑部格栅样光凝对糖尿病性黄斑水肿的疗效，评估TA的两种不同给药方式的安全性。

4 A description of the trial treatment and the dosage and dosage regimen of the investigational product.

6.4.4 试验处理以及研究产品剂量和给药方案的描述。

After IV administration of Aloin and Isobarbaloin mixture solution to six rabbits, the plasma level-time profiles of Aloin and Isobarbaloin were adequately described by an open two-compartment model.

六只家兔於试验设计下，进行指标成分混合液在不同剂量静脉给药试验，结果显示芦荟大黄苷及异芦荟大黄苷在家兔体内之经时浓度变化，初步呈现二室开放模式的趋势。

Results The drug concentration in the abdoninal cavity was highst,the janitrix was secondary,the abdominal aorta and peripheral venous was the lowest .

结果：腹腔给药后药物在腹腔液中的浓度最高，其峰值浓度是外周静脉血中药物浓度的266.7倍，门静脉其次，约11.3倍，腹主动脉，外周静脉血浓度相仿，为最低。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。