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Results:There are alleviating drugs in 79% of the cases, and controlling drugs in 54% of the cases,inhalant was administered in only 8 cases, during which only 5 one took it with correct method, poor compliance were found in 54% of all, controlling and alleviating drugs could not be discriminated in 58% of these cases ,The Dosage was correct in only 3 one, out of the five case who were administered by glucocorticoid inhalant,in no case asthmatic diary or spike current meter was used, The drug adverse reaction was completely non - know in 7 cases.

结果:79%的病人有缓解药,58%有控制药,吸入给药的病人只有8例,其中只有5例使用方法正确,54%的病人用药依从性差,58%的病人不能正确区分控制药与缓解药,在吸入糖皮质激素治疗的5例病人中只有3例剂量正确,无1例病人记录哮喘日记与使用峰流速仪,7例病人对药物不良反应一无所知。

The pH in the lysosome increased 1 h and restored premedication level 4 h after benflumetol administration.

本芴醇单次给药后1 h起疟原虫溶酶体pH值开始升高,药后3 h升至最高,药后4 h原虫溶酶体pH值恢复至药前水平。

In a double-blind, placebo-controlled design we randomized 120 children, aged 1-9 yr, undergoing orthopedic or soft tissue surgery, into 3 groups to receive either acetaminophen 60 mg/kg rectally and 40 mg/kg orally, ketoprofen 2 mg/kg IV twice, or the combination of the active drugs.

在这项双盲、安慰剂对照试验中,我们随机抽取了120个一至九岁的行软组织或畸形矫正手术儿童,将他们分成三组,一组为经直肠给扑热息痛60 mg/kg 或口服给药40 mg/kg ,一组为静脉给优布芬2 mg/kg,另一组为联合给药

Medicine was administered by infusion(γ-amido butyric acid) or alternatively press-spray.

实验给药方法包括灌流给药和压力喷射给药

Another aspect of the present invention provides a kit for vaginal self-use by a female patient in protection against contracting viral infection and against conception as a result of normal heterosexual intercourse, said kit comprising a vaginal applicator comprising a vaginally insertable tubular member having a length of about five inches, and having an aperturable distal end adapted to be positioned adjacent to the patient's cervix when the applicator is fully inserted into the patient's vagina, and at least one unit dose of the spermicidally and virucidally effective formulation described above, said unit dose being from about 5-10 mls thereof.

本发明的另一方面,系给女性患者提供一套阴道自用的工具,以防止感染病菌或因异性间正常性行为而受孕。该套工具包含一个阴道给药器(由一个长约5英寸、末端有孔眼的、可插入阴道的管状构件构成,当给药器全部插入患者阴道后,构件的末端适合置于患者的宫颈附近),以及至少1个单位剂量(5-10毫升)的前述有效杀精和杀菌的配方。

The physical status (body weight,growth rate and appetite), hematological parameters, blood biochemistry, blood cotting, organ index, and tissue pathological changes of rats were checked in the 13th week,and 26th week of the administration and in four weeks after the stop of the administration.

160只SD大鼠,随机分为高、中、低剂量组及空白对照组,雌雄各半,每日灌胃1次,连续给药26周,观察大鼠的一般状况、体重、摄食量和给药13、26周及停药后4周大鼠的血液学、血液生化学、凝血功能、脏器系数、解剖学及病理组织学改变的情况。

Methods: NG108-15 cells were cultured in vitro at 37℃in a humidified atmospherecontaining 5%CO_2. Aβ_(25~35) fragment was dissolved with deionized distilledwater and aged for 4 days at 37℃. The cells were exposured to 5μmol/LAβ_(25~35) for 24h to establish the cell model. Twelve rabbits were divided intotwo groups at random, and garaged with MWD or physiological saline controlrespectively for 7 days to collect two kinds of cerebrospinal fluid, theyare CSF from rabbits treated with MWD and CSF from rabbits treated withphysiological saline.

NG108-15细胞在37℃、体积分数为5%的CO_2培养箱中培养,Aβ_(25~35)溶解于双蒸水中,置于37℃培养箱中老化4d,使其寡聚,毒性增强,细胞被置于浓度为5μmol/L的Aβ_(25~35)中作用24h,建立起AD细胞模型。12只清洁级大耳白家兔购于华中科技大学同济医学院动物中心,将其随机分成两组,分别给与等量的加味温胆汤和生理盐水灌胃7d,末次给药后1h内用水合氯醛将给药组白兔麻醉,1.2ml/kg,无菌条件下用7号注射针头从枕骨大孔处垂直进针,抽取清亮含药脑脊液。

The serums of both groups were collected before the administration, in the week 1, 2, 3 and 4 after the last injection.

并在给药前1天、第2、4、8、12、15、18和20次给药时及停药后第1、2、3和4周采血。

Methods: One hundred and sixty SD rats were randomly divided into four groups (40 in each group), and orally given the medicine with doses of 50, 25, or 12.5 g/kg of crude drug, or with bean oil of 0.5%CMC-Na daily for 26 weeks.

160只SD大鼠,随机分为高、中、低剂量组及空白对照组,雌雄各半,每日灌胃1次,连续给药26周,观察大鼠的一般状况、体重、摄食量和给药13、26周及停药

Methods: One hundred and sixty SD rats were randomly divided into four groups (40 in each group), and orally given the medicine with doses of 50, 25, or 12.5 g/kg of crude drug, or with bean oil of 0.5%CMC-Na daily for 26 weeks.

160只SD大鼠,随机分为高、中、低剂量组及空白对照组,雌雄各半,每日灌胃1次,连续给药26周,观察大鼠的一般状况、体重、摄食量和给药13、26周及停药后4周大鼠的血液学、血液生化学、。。。

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