给药

RESULTSWhen the dosage of the Aipingxiao were 13.0, 6.5g/kg by intragastric administration, the inhibition rates was 34.2％, 28.1% in the transplantation with S180 Sarcoma, the inhibition rates were 50.8%, 40.8% with H22 liver cancer, the inhibition rates were 74.2%, 57.0% with Lewis lung cancer, respectively. The survival rate increased significantly in the hydroperitoneum type of transplantation with H22 liver cancer more than model group.

结果］分别以13.0，6.5g/kg剂量的癌平消灌胃给药，对小鼠移植性S180肉瘤增殖的抑制率分别为34.2%，28.1%，对小鼠移植性H22肝癌实体瘤增殖的抑制率分别为50.8%，40.8%，对Lewis肺癌实体瘤增殖的抑制率分别为74.2%，57.0%，H22肝癌腹水型小鼠的生存时间明显延长，与模型组比较均有显著性差异。

The present invention further provides pharmaceutical compositions comprising the hydroxamic acid derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the hydroxamic acid derivatives in vivo.

此外，本发明提供了药物组合物，其包含所述的异羟肟酸异羟肟酸衍生物，本发明还提供了这些药物组合物的安全的剂量给药方案，其可以容易地遵照，并且其在体内产生该异羟肟酸衍生物的治疗有效量。

It was concluded that the effects of administration of YT by ip and endermosis is contrary to that of administration by po.The Neostigmine-induced hyperperistalsis of the small intestine was inhibited and the inhibitory effect of Atropine enhanced by ip and sc administration of YT suggesting the mechanism of YT involved the antagonism of Ach. But the contraction of isolated rabbit ileum was not inhibited by YT.

对于羊蹄叶水提取物抗腹泻作用机制的研究表明，腹腔注射、皮肤给药YT可明显抑制新斯的明所致小鼠小肠推进功能亢进，也可加强阿托品抑制小鼠小肠推进运动的作用，从而表明YT的作用机制可能与Ach有关，但家兔小肠离体实验表明YT对Ach所致家兔小肠收缩无明显的抑制作用。

Percutaneous delivery of minoxidil would focus on providing a mean to limit the efficacy of hypertrichosis on local site and to avoid the excess of minoxidil entering the blood circulation to proceed with side effects.

Minoxidil局部给药系统之开发研究著重於将毛发增生作用限制於局部，且防止过量的Minoxidil进入血液循环产生副作用。

METHODS: SD rats were randomly assigned into the control group and MCT group. The model of PH was created by injecting hypodermatic MCT. Rapid competitive RT PCR was used to examine the levels of TN mRNA in central pulmonary arteries and lungs at different times after MCT or NS injections.

SD大鼠随机分为MCT组和正常对照组，采用野百合碱皮下注射法诱导建立大鼠肺高压模型，并通过快速竞争性RTPCR技术检测不同时间点(给药后第7，14，21，28天)大鼠肺组织和肺动脉中TNmRNA的表达水平。

To eradicate bovine hypodermosis disease Fenthion spot-on as a new medicine absorbed percutaneously was tested and exploited.

为根除我国牛皮蝇蛆病，试验了一种经皮肤给药透皮吸收的新药剂—点涂剂。

Those with kidney hypofunction should reduce the dose and prolong the period of taking the medicine.

本品主要经肾排出，肾功能减退者须减少剂量或延长给药间期。

OBJECTIVE:To study the hypoglycemic effects of insulin aerosol by pulmonary delivery.

目的：研究胰岛素气雾剂经肺部给药后的降血糖作用。

In vitro evaluations with an Aerolizer inhaler and a multi-stage liquid impinger show that the flaky particles have better aerosol performance because their FPF value could be over 60%, which is 9 times and 1.5 times higher than that of raw material and jet-milled budesonide, respectively.

此外，经肺部给药体外评价，椭圆形片状颗粒具有最优的沉积分布，FPF值高达60%以上，分别比原料药和气流粉碎商品提高了9倍和1.5倍。

It is necessary to strengthen safety education about drug allergy for nurses,including the meaning of drug allergy,recognizing that each drug and each medication route may has allergic reaction and drug allergy test is not the only standard to estimate drug allergy,abiding by nursing technique regulations strictly,guaranteeing the quality of drug allergy test,monitoring drug allergic reactions,recognizing the high incide...

必须对护士加强药物过敏的安全教育；不断学习和认识药物过敏的深刻意义，每一种药物和给药途径均可能发生过敏反应，药物过敏试验不是判断药物过敏的唯一标准，应走出药物过敏的误区；严格遵守护理技术操作规程，把好药物过敏试验质量关；密切观察药物过敏反应，掌握药物高度过敏反应发生的时间，早期发现不典型过敏性休克的症状；熟练掌握过敏性休克的抢救规程，病人对药物过敏的相关内容应有醒目标志。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。