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The neurological deficits and the sizes of cerebral infarction were measured. The contents of MDA and SOD in brains were also tested. Results The neurological deficits and the sizes of cerebral infarction decreased in 6 gingerol treated groups.

缺血组,6 姜酚小剂量组(2mg/kg),6 姜酚大剂量组(4mg/kg),尼莫地平组,缺血前30min舌下静脉给药,持续性缺血6h后处死动物,测定大鼠局灶性脑缺血神经系统症状,脑梗死体积,脑组织MDA和SOD含量的表达。

Objective: To optimize the matrix of Qingnaoxingshen patch. The matrix has high glutinosity, thinness, transparency, and can be used repeatedly.

目的:设计研究一种粘性较高、可反复揭贴、厚度轻薄、无色透明的可用于穴位给药的亲水性贴片基质。

The above data demonstrates that glycocholic acid has the high exhaustion, wide distribution and slow elimination characteristcs in rat which is beneficial to exert the clinical pharmacologic action by keeping the drug concentration for a long time.

结果表明,甘氨胆酸口服给药后,在大鼠体内吸收快、分布广、消除较缓慢,在体内能保持较长时间的药物浓度,有利于其临床药理作用的发挥。

Suitable pharmaceutical carriers (e.g., Eupergit or Glyoxal agarose beads) are known in the art and vary according to the route of administration.

适合药学载体(如Eupergit或Glyoxal 琼脂珠)是本领域中已知的且根据给药途径改变。

The neck of femur were cut and stined with Masson Golder Trichrome for bone histomorphomemetric contrast group analysis.

给药后3、4.5、6个月每组各取10只大鼠进行检测,先测量体重,空气栓塞处死,分离股骨颈,获得股骨颈样本,经切片等处理后,显微镜下作骨形态计量学检测。

The traditional method of giving medicine mainly is the intravenous injection and taking orally, finally arriving the disease focus through the hemal conveyance.

传统的给药方式以静脉注射和口服药物为主,通过血液的运输到达病灶。

Results:①All gallstones type Ⅰ and Ⅳ in animal models were dissolved quickly, however, MTBE showed somewhat toxicity in inhibiting CNS, so that the dose of MTBE should be controlled precisely.②No abnormal change of liver and renal functions of dogs were found before and after operations.③Choloecyst pathological sections of gallbladder suggested that no evident of damage and inflammation of gallbladder was of found. Hemopexis with reversible histological change was observed in hepatic sinusoid and centeral vein short time after administation of MTBE.

结果:①动物模型的Ⅰ、Ⅳ型结石均全部迅速溶解,但MTBE有一定毒性,其对中枢神经系统有一定的抑制作用,应用时须严格掌握单位时间内的灌注剂量及总量(控制在60ml左右);②实验犬实验前后的肝、肾功能检查无异常;③病理检查结果提示MTBE对胆囊组织无明显损伤,无严重炎性反应,给药后短期内肝窦和中央静脉有凝血现象,但其组织学变化是可逆的。

Results: Compared with model group, expression level of BDNF in the hippocampi was significant improved.

结果:与模型组相比,给药组大鼠海马表现为BDNF阳性细胞数量明显增多。

The results showed that noradrenaline, dopamine, homovanillic acid,5 hydroxytryptamine (5 HT) and 5 hydroxyindole 3 acetic acid (5 HIAA) in pallium, striatum, hypothalamus of stressed rats were decreased by piracetam ( 100 mg/kg ; 200 mg/kg )to different degrees and formed a certain relation of amount effect.

对于老年性痴呆、酒精中毒、电休克引起的记忆缺损,儿童智力低下以及脑外伤或手术后意识障碍等均有明显改善和恢复作用。关于吡拉西坦对脑内NE、DA、5 HT等水平的影响因不同剂量、用药时间、以及在给药后不同时间测定递质水平等都会取得不同结果[4~ 6] 。

It also can control malignant hydropericardium effective with slight side effect and deseverd to be generalization on clinical application .

该方法简便易行、安全,腔内给药副作用低,能有效控制恶性心包积液,值得临床推广使用。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

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