给药

The treatment group was given Qizhengxiaotong Emplastrum(0.75 g/kg),and the model group and blank group were given normal saline solution(0.5 mL/each)externally for 5 days on 10th day after the establishment of ...

末次给药后测量各组小鼠的痛行为，包括机械性痛觉超敏和热刺激痛觉过敏；将小鼠股骨进行X线摄片，影像学评估骨破坏；用免疫组化法检测各组局灶皮肤组织肿瘤坏死因子α、内皮素-1(ET-1)、白介素-1β(IL-1β)水平及脊髓后角P物质受体、c-fos及GFAP阳性反应神经元的表达。

And there were no evidence changes in histopathologic analysis of brain tissues in other ETU-injected and in control rat embryos. 2. Results of In situ cell apoptosis detection In E20 cerebral cortex, more Tunel cells were found in encephalocoele group than control group,and the results were significant.

二、应用细胞凋亡原位检测法检测不同组E20胎鼠大脑皮质中细胞凋亡情况 E20胎鼠大脑皮质中Tunel阳性细胞数目在正常组、给药无畸形组及脊柱裂组细胞凋亡数无明显改变，而在脑膨出组胎鼠大脑皮质细胞凋亡数明显多于对照组，计算凋亡细胞百分率，然后用X~2检验进行分析，脑膨出组和对照组的细胞凋亡指数差异有统计学意义(P.05)。

Expression of Caspase-3 and bcl-2 protein In E20 cerebral cortex, the expression of cleaved Caspase-3 in the encephalocoele group are higher than that in control group, and the expression of bcl-2 in the encephalocoele group are lower than that in control group. These findings were consistent with the results of the western blot analysis in E14 Brain.

四、Western-blot检测E14、E20胎鼠大脑皮质中caspase-3、bcl-2蛋白的表达 1、用Western-blot方法检测不同组E20胎鼠大脑皮质中caspase-3、bcl-2蛋白表达水平，结果表明对照组、给药无畸形组、脊柱裂组胎鼠大脑皮质中caspase-3、bcl-2蛋白表达水平无明显改变，而脑膨出组胎鼠大脑皮质中caspase-3蛋白活化片段表达水平明显增加，bcl-2蛋白表达水平明显减少。

AIM: To develop a multi-component DNA delivery system which incorporated hepatocyte targeting ligand, DNA compressing domain and endosome disruptive molecule in one complex.

目的：研制含有靶向配基、DNA聚合亚基、溶酶体活性成分及聚乙二醇等多种组分的肝靶向的DNA给药系统。

Effect on endothelia cells in vivo.

2体内给药对内皮细胞分泌vWF的影响。

Results The main pathologic changes of high dosage group were inflammatory cell infiltration into the tissues around injecting location, subarachnoid space, and ependyma.

高剂量组动物脑组织主要病理改变为给药部位周围脑组织、蛛网膜下腔、室管膜的炎细胞浸润，炎细胞主要以胶质细胞、单核、淋巴细胞为主，没有脑组织的变性坏死。

AIM: To observe the effects of total flavones of epimedium on experimental myocardial ischemia through intravenous injection and gastroenter-administration pathway.

目的：观察淫羊藿总黄酮静脉注射和胃肠道给药途径对实验性心肌缺血的影响。

On an equimolar basis (100 mol/kg), nalbuphine base produced a 6-fold increase in the duration of action than did nalbuphine HCl.

在相同的给药剂量下（100微莫耳／公斤），新型注射液比传统注射液延长了6倍的止痛效期。

Methods Sulfanilamide was injected by abdominal cavity and by gavage as the photosensitizer in mice and guinea pig, Then the ear thickness of mice was measured and the erythematic reaction of guinea pig was observed at 4 h, 24 h, 48 h after induced by UVA plus UVB or only UVA.

以对氨基苯磺酰胺作为光敏剂，经腹腔注射与灌胃两种途径对小鼠和豚鼠进行给药，通过UVA加UVB光照诱导以及只用UVA光照激发后，于4h、24h、48h和72h分别测量小鼠耳厚度及观察豚鼠皮肤红斑反应。

Result:Only at an excessively high dose can the medicines raise the erythrocytic osmotic fragilitas of G6PD deficiency in rats.

结果：G6PD缺陷大鼠红细胞渗透脆性仅在超大剂量给药时才有所增高。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。