给药

The mice were killed 3, 7 and 14 days after operation (8 mice per group at a time), the tissue of cystiform was harvested to receive gross, histology and immunohistochemistry observation, as well as RT-PCR and Western blot detection.

术后观察动物一般情况，于给药后3、7 及14 d，每组取8 只小鼠背部囊壁组织行大体、组织学观察及免疫组织化学、RT-PCR、Western blot 检测。

Provincial Key Laboratory for Chinese Drugs Processing,Nanjing 210029,ChinaObjective:To investigate the intestinal absorption of daphnetin and the mechanism using Caco-2 monolayer model.

目的：研究祖师麻甲素在Caco-2细胞模型中的吸收特性，为其及祖师麻给药途径的选择和剂型的合理设计提供依据。

Methods The rat models of heart failure were established by left anterior descending coronary artery deligation. After 6 w, 24 surviving rats were divided into sham,model and Ramipril groups at random,8 rats in each,and were treated with medicines by intragastric administration respectively. At 10 w, left ventricular enddiastolic pressure, left ventricular systolic pressure,+dp/dtmax anddp/ dtmaxof left ventricular pressure were measured.

结扎大鼠左冠状动脉前降支并饲养6 w的16只存活大鼠，随机分为模型组及雷米普利组，每组8只，另取8只大鼠为假手术组，连续灌胃给药4 w后测定大鼠血流动力学参数，ELISA方法检测血清及左心室非梗死区AngⅡ的含量，RTPCR 法测定左心室非梗死区心肌组织AT1R mRNA表达水平，Masson染色观察非梗死区心肌胶原的沉积。

AIM: To investigate the transdermic absorption and ac cumulation in vivo after dermic administration of 1% liquor of terbinafini hydrochloridum.

目的观察1%盐酸特比萘芬溶液经皮肤给药后药物在体内的吸收性和蓄积性。

Nepalensis wall polysaccharide was prepared with hot water extraction,ethanol precipitation,dialyzation,and lyophilization.the crude polysaccharide was separated by deae-cellulose chromatography and purified by sephadex g-200 chromatography.the inhibit effect of the polysaccharide on lipid peroxidation of mice liver was conducted by tba method.the model of liver-injury induced by carbon tetrachloride（ccl4was used to validate the variety of the realated ast.results onefold ingredient polysaccharide was obtained after isolated and purified.conclusion the ingredient can remarkably inhibit lipid peroxidation of rat liver and significantly reduce activity of ast.

用热水提取，乙醇沉淀提取粗多糖，再经sevag法去除蛋白，透析去除小分子物质，冷冻干燥得楮头红多糖粗品；采用deae-52纤维素柱层析和sephadex g-200凝胶柱层析进行分离纯化；用tba法考察多糖的抗脂质过氧化作用；采用ccl4急性肝损伤模型，测定其血清中ast变化。结论获得一个楮头红多糖组分。tba法表明该组分对小鼠自发性脂质过氧化具有显著的抑制作用；在保肝试验中，给药组能明显抑制ast的升高，对肝损伤有一定的保护作用。

After 4 weeks, being continuously administrated, the mice were tested the blood glucose by adopting tail vain blood; plasma fructosamine, Hb diastatic value, and kidney and liver protein diastatic value.

连续给药4 w后应用采取尾静脉血检测其血糖水平；血浆果糖胺和Hb糖化值及胰腺、肾和肝脏蛋白糖化值。

136 cases of pointed condyloma were treated in the center. The surface of the lesion area was first treated with dichloroacetic acid for 15 minutes, and washed with normal saline, then MEBO was applied to the lesion area. MEBO was applied every 6 to 8 hours(3 to 4 times a day) and 8 cases of the same disease were treated with MEBO 2 times a day(every 12 hours), 3 cases with large lesion areas were treated more frequently.

用二氯乙酸涂抹疣体表面15分钟，再用生理盐水擦洗，即于疣体表面及带部涂MEBO.136例患者每6小时～8小时给药一次，8病例每12小时用药一次，疣体较大范围较广泛的3例患者，增加换药次数，并行分期治疗。

Methods: All the patients recruited were randomized into the diclofenac diethylamine salt gel and diclofenac sodium gel groups and treated with local application three times daily for 14 days respectively.

4 0例患者随机分为双氯芬酸二乙胺盐凝胶组和双氯芬酸钠凝胶组进行临床对照试验，分别采用局部涂擦给药法，tid ，14d为 1疗程。

Objective: To study the appropriate dose of sparfloxacin dispersible tablet given orally and through interven tional approach.

目的：研究司帕沙星分散片口服给药和局部介入治疗用药量的依据。

The two groups were given the same regime, treatment group forty cases were given herb Feifu-decoction one dosis, twice per day. Control group forty cases were only given anti-tuberculosis drugs. The course of treatment was one month.

两组患者在给予相同抗结核药物治疗的基础上，治疗组40例，每日1剂中药肺腑汤剂，分2次给药；对照组40例只给予口服抗结核药物治疗，疗程均为1个月。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。