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METHODS:AsOR was conjugated to PL by EDC; The active ester of PEG derivative was reacted with the amino groups in PEI to form PEG-PEI conjugate; DNA was first complexed with PEG-PEI and then with AsOR-PL. In vitro transfection experiment was conducted in the galactose receptor positive Huh-7 cells.

分别制备AsOR-PL偶合物及PEG-PEI偶合物,然后按照不同的比例先后与报告基因DNA形成复合物,再进行Huh-7细胞的体外转染试验和静脉给药后小鼠体内的表达试验。

However, long-term efficacy needs to be assessed and different schedules of combination need to be evaluated.

然而,其长期的效果需要进一步的评估和进行不同给药方案的联合治疗实验。

Methods We adopted the myocardial ischemia rat model by ligaturing their front-fall branch of left coronary attery, and tested the convey of VEGF in myocardium cell by means of immunohistochemistry 21 days after having given Cornu Cervi.

方法采取结扎大鼠冠状动脉左前降支的方法复制心肌缺血模型,在给药21天后运用免疫组织化学SABC法测定其心肌细胞血管内皮生长因子的表达。

Objective To investigate the anti-fatigue effects of the Chinese medicine complex which in-cludes Ant and Aweto etc,and further to determine the only dosage.Methods 192Kunming mice were randomly di-vided into sixteen groups.After being given orally medicine or distilled water for4weeks,the sixteen groups of mice were respectively experienced swimming,over8000m hypobaric hypoxia or jumping stand test.

目的 观察以玄驹和冬虫夏草主要成分的中药复方制剂抗疲劳等药效作用,进步选择并确定最佳用药剂量方法将昆明雄性小鼠192只随机分为16组,灌胃给药4周后,分别进行持续游泳、8000m以上高空低压缺氧及跳台实验。

The safety evaluation of the solid lipid nanoparticles which was mainly made of Glyceryl behenate had been made to inquiry the possibility that it fitted for intravenous administration.

对以山嵛酸甘油酯(ATO,Glyceryl behenate)为主要载体材料的固体脂质纳米粒(SLN,solid lipid nanoparticles)做安全性评价,探讨其作为静脉给药系统的可能性。

Results The compounded gum was combined with bletilla hyacinthine gum and PVA in the proportion of 5:1 so that its adhesive ability and membrane forming ability were suitable for giving medicine through airway.

在临床工作中,由于全身用药对肺局限性病灶常存在穿透力不够而在局部无法达到有效浓度的情况,往往需要采用从气道内直接给药的方法,如厚壁结核空洞、局灶性化脓性病变等[1 ] 。

In lungs, AQP1 was abundant in peribronchiolar capillaries, postcapillary venules, bronchiolar basal membrane and alveolar epithelial cells.

结果表明,托吡酯在给药剂量范围内(0.068μg-6.8μg/鸡胚)可抑制鸡胚尿囊膜的血管生成,剂量为0.68μg/鸡胚和6.8μg/鸡胚时抑制效果明显,最高抑制率达33.5%。

The present agents may be administered in an anti-bronchoconstriction and/or anti-inflammation effective amount to alleviate the bronchoconstriction and inflammation afflicting a subject.

本发明药剂可以以抗支气管狭窄和/或抗炎症的有效量给药,以减轻个体的支气管狭窄和炎症。

AIM To investigate the hypoglycemic effect of buccally delivered insulin solution in normal rats.

目的 研究胰岛素溶液(insulinsolution ,INS SOL)经正常大鼠口腔给药后的降血糖作用。

MethodsThe acute hepatic injury model made by D-GalNactosamine and alcohol after i.g. mice the Caesalpinia minax Hance for 7 days, then the activities of alanine aminotransferase and aspartate aminotransferase in serum were examined.

方法苦石莲总提取物灌胃给药7 d后,用D-GalN、酒精导致小鼠急性实验性肝损伤,检测小鼠血清谷丙转氨酶、谷草转氨酶活性和肝脏系数。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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