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Results The level of cortisol in group Ⅰ of each point were higher than the normal; The level of cortisol in group Ⅱ at the time of intubations were higher than the normal; The level of cortisol

结果 Ⅰ组术中各时点皮质醇水平高于正常值,Ⅱ组插管时皮质醇水平高于正常值,Ⅲ组各时点皮质醇水平在正常值范围内;Ⅱ、Ⅲ组皮质醇水平随给药时间延长而下降;所有患者术后第1日晨皮质醇恢复正常。

Results The level of cortisol lunwen114in group Ⅰ of each point were higher than the normal; The level of cortisol in group Ⅱ at the time of intubations were higher than the normal; The level of cortisol in group Ⅲ were in normal at each point.

结果 Ⅰ组术中各时点皮质醇水平高于正常值,Ⅱ组插管时皮质醇水平高于正常值,Ⅲ组各时点皮质醇水平在正常值范围内;Ⅱ、Ⅲ组皮质醇水平随给药时间延长而下降;所有患者术后第1日晨皮质醇恢复正常。

Results The level of cortisol in group Ⅰ of each point were higher than the normal; The level of cortisol in group Ⅱ at the time of intubations were higher than the normal; The level of cortisol in group Ⅲ were in normal at each point.

结果 Ⅰ组术中各时点皮质醇水平高于正常值,Ⅱ组插管时皮质醇水平高于正常值,Ⅲ组各时点皮质醇水平在正常值范围内;Ⅱ、Ⅲ组皮质醇水平随给药时间延长而下降;所有患者术后第1日晨皮质醇恢复正常。

Results:The level of cortisol in group-Ⅰ of each point was higher than the normal; The level of cortisol in group-Ⅱ at the time of intubations was higher than the normal; The level of cortisol in group-Ⅲ was in normal at each point. The cortisol of group-Ⅱ and Ⅲ were degressive with the time. The level of cortisol in all the patients recovered in the first morning of post-operation.

结果:I组术中各时点皮质醇水平高于正常值,Ⅱ组插管时皮质醇水平高于正常值,Ⅲ组各时点皮质醇水平在正常值范围内;Ⅱ、Ⅲ组皮质醇水平随给药时间延长而下降;所有患者术后第1天晨皮质醇恢复正常。

The cortisol of group Ⅱ and Ⅲ were degressive with the time. The level of cortisol in all the patients recovered in the first morning of post-operation. In group Ⅰ, the level of blood glucose increased at the times of intubations, and glucose-tolerance-test shows abnormal.

结果 Ⅰ组术中各时点皮质醇水平高于正常值,Ⅱ组插管时皮质醇水平高于正常值,Ⅲ组各时点皮质醇水平在正常值范围内;Ⅱ、Ⅲ组皮质醇水平随给药时间延长而下降;所有患者术后第1日晨皮质醇恢复正常。

The ion exchange resin offer the new consider and method for the new drug delivery system.

离子交换树脂在药物制剂领域倍受关注,为新型给药系统的研制提供了新的思路与方法。

METHODS: Sixty Kunming mice were divided in normal group, irradiative injury group, and EbD-treated groups (100, 300, 500 mg/kg).

昆明小鼠60只随机分为:正常组、辐射组、不同剂量(100,300,500mg/kg)胡颓子多糖给药组。

In addition, the reagent in O-T method are more toxic and irritative, so GOD method adopted in this paper.The stability of INS in digestive secretion was investigated. The results show that the degradation rate in gastric solution was so fast that any pharmaceuticalmodification and adding enzyme inhibitors could not protect it.

在肠道吸收部位的研究中发现,INS溶液在大肠处给药可有微量吸收,但能引起动物血糖的明显下降,INS的水溶液和微乳液的吸收与药效无明显差异;在小肠处,INS溶液不能吸收,也不能引起大鼠血糖的降低,而制成微乳液后,可经小肠粘膜吸收,并引起血糖的明显下降。

Methods: According to the refe-rence of new traditional Chinese medicine study, maximal dosage of drug was given to rabbits to do the acute toxicological and irritative test on skin. The guinea pig was used to do the skin hypersensitive test with excipient as negative control and 1% 2,4-dinitrochlorobenzene as the positive control.

参照中药新药研究指导原则,采用最大给药剂量法对大白兔进行皮肤用药急性毒性和刺激性试验;以赋形剂为阴性对照,1%的2,4-二硝基氯苯丙酮溶液为阳性对照,对豚鼠进行皮肤过敏性试验。

The NNP (10 mg/kg) or solvents was injected 10 min before ischemia via jugular vein.

NNP(10 mg/kg)或溶剂在缺血模型形成之前10 min经颈静脉给药

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