给药

Stable pharmaceutical compositions containing 8-chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6] cycloheptic [1,2-b] pyridine and a DCL protective amount of a pharmaceutically acceptable basic salt such as calcium dibasic phosphate and an amount of at least one disintegrant, preferably two disintegrates such as microcrystalline cellulose and starch sufficient to provide dissolution of at least about 80% by weight of the pharmaceutical composition in about 45 minutes and suitable for oral administration to treat allergic reactions in mammals such as man are disclosed.

本发明公开了含有8－氯－6，11－二氢－11－（4－亚哌啶基）－5H－苯并［5，6］环庚三烯并［1，2－b］吡啶和DCL保护量的可药用碱性盐如磷酸氢钙以及其含量足以使至少约80％的药物组合物在约45分钟内溶解的至少一种崩解剂、优选两种崩解剂如微晶纤维素和淀粉并且适于口服给药以治疗哺乳动物、例如人的过敏反应的稳定的药物组合物。

CNP was given intravenously and its actions of lowering blood pressure and diuresis were observed.

整体大鼠静脉给药，观察CNP的降压和利尿作用。

The prerenal mechanism to the action of diuresis of CNP may be the effect of expanding renal artery.

CNP具有肯定的弱利尿作用，其扩张肾动脉可能是CNP利尿作用的肾前机制；CNP的降压作用不依赖其利尿作用，扩张外周动脉可能是整体给药时降压的一个因素，而CNP的心抑制效应则是降低血压的主要原因。

MethodsA total of 24 RCS rats were evenly divided into treatment and control group in random.

RCS大鼠24只，随机分为给药组和对照组，各12只。

Receptor binding was found to be increased by 26%(p.05) in 6-OHDA lesioned side vs contralateral side in control rats. After 42-day administration of 1-dopa,〓 was reduced by 20%(p.05) in lesioned side. There was almost no difference of 〓 between 〓-dopa+〓-SPD-treated and vehicle-treated rats.

6—OHDA毁损的大鼠，给药42天后〓受体结合分析，对照组大鼠毁损侧〓受体增生，Bmax增加26%（P.05）；应用1—dopa组〓受体Bmax减少20%（P.05）；而1—dopa+1—SPD组〓受体与对照组相比无明显变化。

It was observed that the PPD mRNA expression in supraoptic nucleus, paraventricular nucleus of hypothalamus and nucleus raphe dorsalis was stronger in the brain sections of rats treated with melatonin than in those treated with vehicle.

结果观察到，给药组大鼠视上核、下丘脑室旁核、中缝背核内神经细胞的PPD mRNA表达明显强于对照组；其IOD值均显著高于对照组(P0.05)。

The concentration of DOX in tumor and the apoptotic rate in cancer cell were all higher in DOX plus CWQ group than that in other groups.

结果 阿霉素和肠胃清单独给药均不能抑制肿瘤组织的生长，阿霉素与肠胃清联合能显著减少肿瘤组织的重量，增加肿瘤组织内的阿霉素浓度，诱导肿瘤细胞发生凋亡。

They were fed with medicine intragastrically. The earlap inflammation caused by bimethylbenzene, the effect on pain induced glacial acetic-acid, the influence on the penetrability of capillary vellset in the abdominal cacity and the weight of rat cotton-ball granuloma were observed. 2.Acute toxicity test: Twenty mice were fed with the rhinitis capsule solution of most concentration and volume by intragastrically. All the actions and the appearance of major organs were observed in twenty-four hours and one week.

分别灌胃给药，观察该药对小鼠二甲苯性耳壳炎症、冰醋酸致痛作用及冰醋酸致腹腔毛细血管通透性增高和大鼠棉球肉芽肿的影响。2、急性毒性实验：20只小鼠灌胃给以最大浓度和最大剂量鼻炎胶囊溶液，用药24小时和1周后观察动物的一切活动及各主要脏器的外观形态。

The effect of Jiusuyu on ebriety rate,ebriety time of acute alcoholism mice observed after preventing treatment The heal...

酒速愈预防性给药对急性酒精中毒小鼠醉酒时间、醉酒率的影响健康昆明种小鼠，雌雄各半，随机分为4组：模型组、酒速愈低剂量组(灌服酒速愈16.2g生药/Kg体重)、酒速愈高剂量组(灌服酒速愈32.4g生药/Kg体重)、葛花解酲汤组(灌服葛花解酲汤13.1g生药/Kg体重)，每组20只。

First we made asthma mice model with the method of inject egg albumin in the mice s abdominal.

在经腹腔注射卵蛋白造模后，中药组与激素组每日进行预防给药。14日后激发小鼠哮喘发作，并进行CD4、 TCR、MHC Ⅱ等指标的观测，应用PEMS 3。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。