给药

Its toxicity was recorded in the period and in 14 days of convalescence.

用♀和♂大鼠进行口服给药 6 0天及恢复期 14天的毒性研究。

Methods: Totally 16 healthy adult rabbits of both sexes were randomly divided into SP group and NS group. The rabbits in SP and NS group were given Thiopental (3 mg/kg) and normal saline (1 ml/kg) respectively by intravenous injection via ear vein after establishing convulsant models by injecting Strychnine into the other ear vein. QPEEG and power spectral analysis were used to analyze the changes of δ-band of QPEEG in convulsant rabbits before and after administering drugs.

成年家兔16只，雌雄不限，随机分为硫喷妥钠组和生理盐水组，每组8只，在建立惊厥兔模型后，分别耳缘静脉注射硫喷妥钠3 mg/kg、生理盐水1 ml/kg，应用QPEEG，采用功率谱分析法，分析惊厥家兔给药前后QPEEG δ频段的变化。

The animals were divided into three groups: groupⅠ: control ; group Ⅱ: NIDDM model ;group Ⅲ: NIDDM model + Cornus officinalis Sieb.et Zucc.

将动物分为 3组，每组 6只：①正常对照组，②NIDDM模型组，③NIDDM模型+山茱萸乙醇提取液给药组。

Model group and the normal group were taken distilled water,rats in the Tangshukang group were taken Tanggukang powder, western medicine control group were taken Calcium Carbonateand alpha D3. once a day for 12 weeks. Ca,P, BALP,BGP in blood and bone miner density;bone mineral contents, osseous vitodynamics,the content of Ca and P in the cremains were tested respectively.The femur was taken and detected the expression of TGF-β_1imRNA , the duodenum was taken and detected expression of VDR mRNA and CaBp-D9K mRNA with situ hybridization.

分别给予糖疏康、碳酸钙阿法迪三和生理盐水灌胃给药。12周后取材，测体重、血糖、血清钙、磷、血清骨源性碱性磷酸酶、骨T-羧基谷氨酸蛋白、骨密度、骨矿含量、骨的生物力学、骨干重、灰重、骨钙、磷等指标、组织病理切片骨形态计量学指标测定、并进行维生素D受体mRNA、转移生长因子-β_1(TGF-β_1)mRNA、钙结合蛋白(CaBp-D9K)mRNA原位杂交。

The single-dose administration of Asp/Lze (ig 100/100mg/kg) apparently prolonged cruor time in vitro and the bleeding time of tail in mice .

Asp／Lze(ig100／100mg／kg)单次给药，可显著延长小鼠体外凝血时间和小鼠尾出血时。

Toxicologic study of water soluble extract and ethanol soluble extract of DEH was observed.

目的观察土甘草水提物和醇提物对小鼠灌胃给药的急性毒性。

Objective: To explore the clinical effect of dermal medication on children virus enteritis.

目的：探讨经皮给药治疗小儿病毒性肠炎的临床疗效。

Methods Vacuole incidence of axillary sweat gland was determined by observing the histolomorphological changes of vacuole to evaluate the diaphoretic function.

方法采用组织形态学方法，以大鼠腋窝部皮肤汗腺的空泡发生百分率作为评价发汗强度的指标，观察麻黄汤不同配伍给药后30 min对大鼠的发汗作用。

EDD and NEDD of external iliac artery in vivo (measured with high-resolution ultrasound), serum lipids, NO, NOS, plasma ET, ADMA, symmetric dimethylarginine and L-arginine, the area of AS plaque in thoracic aorta (dyeing with Sudan Ⅳ), the degree of AS lesion in abdominal aorta and external iliac arteries, NOS activity on the wall of the abdominal aorta, the expression of iNOS mRNA and eNOS mRNA on the wall of the abdominal aorta and the contractive and dilatant functions of abdominal aorta and external iliac arteries in vitro; B. the activities of dimethylarginine dimethylaminohydrolase in kidney (including the establishment of the determining method). 3. In the third part of the study, normal aorta strips were used. The following were surveyed: their response to using ADMA alone, influence of treating with ADMA, intervention of polydatin, influence of using ADMA and PD together on Emax and Kd that were contracted by PE.

第5组为未给药组。2、观察指标：A、各组髂外动脉EDD和NEDD、血脂、血清NO和NOS活性、血浆ET、ADMA、SDMA和L-精氨酸水平、胸主动脉AS斑块面积、腹主动脉和髂外动脉AS病变积分、腹主动脉壁NOS组织化学染色和eNOS mRNA和iNOS mRNA表达及离体腹主动脉与髂外动脉舒缩功能。B、各组兔肾DDAH活性。3、离体做正常主动脉条对单用ADMA的反应、PD和ADMA对PE收缩效应的影响及PD预处理对受ADMA作用的正常主动脉条PE收缩反应的影响(包括对Emax和Kd值的影响)。

Patients have to reduce dosage or dose discontinuously because of Acute Renal Failure caused by cisplatin and this limit the full clinical utility of cisplatin.

但是，在顺铂化疗的同时会产生严重的毒副作用，其中肾毒性表现得最突出，化疗病人往往因为急性肾衰而不得不减量或间断给药，使顺铂达不到有效的治疗剂量。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。