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The present invention relates to medicine technology and is especially one kind of new preparation form. The transdermal plaster is noe kind of antiphlogistic containing Flubiprofen, Ketoprofen, Ibuprofen, Rosorolfen, Naproxan and other aryl propionic non-steroid.

本发明涉及医药技术领域,特别是氟比洛芬、酮洛芬、布洛芬、罗索洛芬和萘普生等芳基丙酸类非甾体抗炎药的透皮给药制剂中一种新剂型――透皮贴剂。

Objectives: To investigate the dosage regimen of Digoxin with relation to its blood concentration and therapeutic effect.

目的:探讨地高辛给药方案对血药浓度及临床疗效之间的关系。

Pharmaceutical characteristics of dimethylamino ethyl(4-chlorophenylmethfoxy )acetate hydrochloridein rabbit was studied and several parameters at different timeand way of medicine administration were determined.

研究了4-氯代苯甲氧基乙酸二甲氨基乙酯盐酸盐在家兔体内的药代动力学,测定了不同时间不同给药方式家兔体内的血药浓度及动力学参数。

Pharmacokinetics of indirubin-loaded PLCS in rat in vivo was compared with that of indirubin suspension.

最后进行载药纳米胶束腹腔注射给药后在大鼠体内的药动学实验,与靛玉红混悬剂对照。

Serum containing SSTG was obtained at different time after perorally administrated with different dose of SSTG.The cardiomyocytes were deprived of oxygen and glucose to mimic hypoxia reoxygenation injury and were treated by serum containing SSTG when reoxygenation.LDH content in supernatant was detected after reoxygenation.LDH release suppression rate was used to study the time-effect and dose-effect of serum containing SSTG.

以中药有效组分配伍方剂双参通冠方不同灌胃剂量、药后不同取血时间所得的药物血清为受试药物;培养心肌细胞,进行缺氧复氧实验,复氧同时给予不同双参通冠方药物血清处理,实验结束后取培养上清检测LDH值,以LDH释放抑制率为指标,观察含药血清药理作用强度与体内给药的量效、时效关系。

Major advantages of transdermal drug delivery system include avoiding of drug degradation in hepatic and gastrointestinal,predetermining release rate and blood drug level,reducing administration frequency and adverse reactions,and increasing patient compliance.

透皮给药系统可有效避免肝脏首过效应及胃肠道降解,调控释药速率和血药浓度,降低不良反应及用药频率,提高患者顺应性。

Where are you you, I am in Beijing, baby in my home three and a half months when diarrhea, there are seven or eight times a day, go to the hospital they said La dysentery, to open the medicine, good food to eat for three days later went Children's Hospital, the doctor also said to be eating dirt,药吃opened the next day just fine.

你在哪呀,我在北京,我家宝宝在三个半月的时候也拉肚子,一天也有七八次,去医院人家说是拉痢疾,给开了药,吃了三天没吃好后来就去了儿童医院,大夫也说是吃了脏东西,开了药吃了第二天就好了。

The control mice were injected subcutaneously with 5mL·kg-1 saline once daily,and the mice of the aging model group,with 5g·kg-1 D-galactose once daily,and the mice of low,middle and high dosage groups of Baishen oral liquid,after their aging models were induc...

空白对照组皮下注射生理盐水,5g.mL-1,1次/天,衰老模型组皮下注射D-半乳糖(5g.k-g 1),1次/天,各给药组在D-半乳糖致衰老的基础上,不同剂量连续给药42d后,处死,采血,分离血清并测定生化指标。

ResultsIn the writhing test, 10 mg·kg-1 of Nudicaulol significantly reduced the number of writhing induced by ip 0.05% antimony potassium tartrate, in the hot plate test, 10 mg·kg-1 of Nudicaulol significantly enhanced threshold value of pain induced by thermal stimulation in 30, 60 and 90min after sc Nudicaulol.

均皮下注射给药。采用小鼠扭体法、热板法观察药后30 min各组小鼠的扭体反应次数和热板法药后30,60,90 min的痛阈值。结果10 mg·kg-1努地可醇可明显减少扭体次数、提高痛阈值,与生理盐水组比较差异(P<0.01)。

Objective: To observe production of antibody to rhbFGF, its neutralizing activity and deposition in kidney in conducting toxicity study on repeated doses of recombinant human basic fibroblast growth factor in normal rhesus monkeys and Wistar rats.

目的:在猕猴和大鼠中进行重组人碱性成纤维细胞生长因子的重复给药毒性试验时,观察给药后抗 rhbFGF 抗体的产生和抗体的中和性,以及抗体在肾脏的沉积。

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