给药

Results:scutellarin is more rapidly and thoroughly absorbed following intratracheally sprayed to the rat lungs,relative to after peroral administration and pulmonary delivery of scutellarin seemed to eliminate from the intestinal and hepatic first pass metabolism occurred during oral delivery of the drug with the absolute pulmonary bioavailability at the dose of 10 mg/kg against intravenous controls being determined to be about 77%,which was more than 30 folds higher than that given by peroral administration.

结果灯盏乙素溶液经大鼠气管喷雾给药后的绝对生物利用度程剂量线性相关，10mg/kg剂量时F约为77%，是灌胃给药后F的约30倍，并且能够避开首过效应。

We successfully modified the gavage method in guinea pigs, which would definitely take guinea pigs involved in intragastical pharmacal experiments besides the routine of rats and mice.

成功改良了豚鼠的灌胃给药方法，使经口给药途径的动物实验不需因技术问题而局限于大鼠、小鼠，为进一步的药物和营养学等研究奠定了基础。

This approach, by reducing the peak serum surge, largely resembles the pharmacokinetic and pharmacodynamic advantage of continuous infusion.

这样的给药方式减少了巅峰的血中药物浓度，在药物动力学方面的作用类似持续殂脉给药的方式。

Hepatic ischemia was indeed by Pringle's maneuver and then one or three hours reperfusion was performed.

SF组给予参附注射液10ml/kg，腹腔注射，每日1次，连续给药6d，第6天于手术前30min给药。

The bronchial asthmatic model was established by egg protein sensibilization and longterm inhalation provocation.The rats of each treatment groups were lavaged each day from the first time of provocation to execution.After 4 weeks of treatment,the rats were killed to obtain lung tissue for dyeing of HE.A computer assisted image analysis system was used to determine the thickness change of bronchus wall and smooth muscle.The contents of MMP9 and TIMP1 in lung tissue were determined by ELISA double antibody sandwich method.

除正常组外以卵蛋白致敏并吸入激发法制备大鼠支气管哮喘模型，各治疗组均从第1次哮喘激发开始(造模第3周)至处死前每天灌胃给药，激发并给药4 w后处死大鼠，取肺组织HE染色，彩色图像分析仪测量支气管管壁厚度、平滑肌厚度，采用ELISA双抗体夹心法测定肺组织MMP9、TIMP1含量。

In comparison with the control group, the time to falling asleep and the duration of sleep due to supraliminal dosage of sodium pentobarbital were shortened and prolonged significantly, respectively,in the small-dosage and large-dosage groups.

橙皮水提取物小剂量给药组，大剂量给药组能显著加速阈上剂量戊巴比妥钠的入睡时间和延长戊巴比妥钠的睡眠时间，差异有显著性意义。

Electrophysiological index before and after injection was recorded by using electromyograph so the neural electrophysiological influence by the injection could be observed.

用丹迪CANTATETM型肌电图仪检测用药前每组动物的电生理指标及用药组每次给药后的电生理指标，来观察硬膜外腔给药是否会对实验动物的神经电生理产生影响；5。

We separately poured medicine into their stomaches with BF and CERA by contrasting with two groups of normal and model once a day.

预防给药实验组在末次灌胃后1h以0.2%CCl4 0.2ml腹腔注射制作小鼠实验性肝损伤模型，治疗给药实验组在首次灌胃后1h以0.2%CCl4 0.2ml腹腔注射制作模型。

Admixed solutions are stable for 24 hours at 2°C to 8°C (36°F– 46°F) and at room temperature.

前4周每周给药600mg，第5周给药剂量为900mg，……。。混合溶液在2°C - 8°C或室温下24小时内稳定。

Although 600 mg has been described as the maximum absorbed dose when given as a single bolus, the effects of 2 boluses given 24 h apart have not been described.

尽管600mg曾被描述为单次给药的最大吸收剂量，但2次给药间隔24小时的疗效尚不清楚。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。