给予...大剂量

Objective:To compare the effects of different dosage of dexamethasone on rat lung morphogenesis.

目的：比较生后给予不同剂量地塞米松(dexamethasone，DEX)对大鼠肺组织形态发育的影响？

Methods A randomized, study was used in patients who received HD-DDP (100mg/m^2) treatment. All patients were randomized into the test group (used HD-DDP and arginine) and the control group (used HD-DDP along). L-arginine was used simultaneously with DDP and the dosage was 10g/(m^2d).β2-MG in urine before and 24 hours after using HD-DDP were measured respectively. The varity of β2-MG were examined and analysed.

对适合用大剂量顺铂(100mg/平方公尺)化疗的患者随机分为研究组和对照组，两组形成自身对照（即1例患者的2个周期进行自身对照）。L-精氨酸的用法为10g/，在用顺铂的当天给予，比较研究组与对照组化疗后24h尿β2-微球蛋白(β2-MG)的变化。

Methods A randomized, study was used in patients who received HD-DDP( 100 mg/m2)treatment.All patients were randomized into the test group(used HD-DDP and arginine)and the control group(used HD-DDP along). L-arginine was used simultaneously with DDP and the dosage was 10 g/(m2· d).β2-MG in urinebefore and 24 hours after using HD-DDP were measured respectively. The varity of β2-MG were examined andanalysed.

对适合用大剂量顺铂(100mg/m2)化疗的患者随机分为研究组和对照组，两组形成自身对照(即1例患者的2个周期进行自身对照)。L-精氨酸的用法为1O g/(m2·d)，在用顺铂的当天给予，比较研究组与对照组化疗后24 h尿β2-微球蛋白(β2-MG)的变化。

Methods 54 Wistar rats were injected abdominally with lithium by 6 different periods later within 3 days, different dose of pilocarpin was injected.

54只wista大鼠腹腔注射氯化锂3mmol/kg，在三天内分六个时间段给予不同剂量的匹鲁卡品腹腔注射。

1Casegastrectoˉmy stoma ulcer in Group B,1case melena in Group C.Conclusion The result shows that high-dose successive adˉministration of MP can improve postoperative neurological functions recovery of CSM significantly.The usage of MP above-mentioned is safe,except that we should pay close attention to special case.

MP大剂量连续应用能明显提高脊髓型颈椎病术后神经功能的恢复；MP的上述用法是安全的，但对消化道并发症应给予关注。

METHODS: Male Sprague-Dawley rats were given repetitive doses of IT morphine (40 microg x 2) at 1 and 5 h after a noninjurious interval (6 min) of spinal cord ischemia.

使用雄性 Sprague-Dawley 大鼠，在经历一段时间非损伤性脊柱缺血(6分钟)后的1小时和5小时，重复给予一个剂量的吗啡鞘注(40μ g ×2)。

objective:to investigate the influence of soybean isoflavones on the antioxidative effect and improving the ability of study and memory in climacteric rats.methods:forty-eight female sd climacteric rats were randomly divided into 4 groups with one control group and the other low,medium and high dose groups,which were given soybean isoflavones 0 mg/kg.bw,42 mg/kg.bw,83 mg/kg.bw and 249 mg/kg.bw by superalimentation daily for 60 days respectively.the levels of sod,gsh-px and mda in serum were measured,and the ability of study and memory in each group was deterimined by adopting the law of diving platform.results:the content of serum mda in medium and high dose groups was lower than that in control group.the activity of serum gsh-px im medium and high dose groups was significantly increased,so was the activity of serum sod in low,medium and high dose groups.conclusion:soybean isoflavones do have the obvious effect of antioxidation,and improve the ability of study and memory effectively in female sd climacteric rats.

目的：观察大豆异黄酮对更年期雌性sd大鼠抗氧化作用及学习记忆的影响。方法：选用健康更年期雌性sd大鼠，随机分成空白对照组和低、中、高剂量4组。空白对照组给予蒸馏水，实验组每日分别灌服42、83、249 mg/kg剂量的大豆异黄酮，连续60d。第60d取血测定血清过氧化脂质丙二醛含量、超氧化物歧化酶活力、谷胱甘肽过氧化物酶活力，用跳台实验方法测定大鼠学习记忆能力。结果：与空白对照组比较，中、高剂量组大鼠血清mda含量显著降低，低、中、高剂量组血清sod活力明显升高，中、高剂量组血清gsh-px活力明显升高。结论：大豆异黄酮具有明显的抗氧化作用，并有效提高更年期雌性sd大鼠的学习记忆能力。

Although methadone administration did not produce hemodynamicinstability in this study, the possible hemodynamic side effectsof histamine release should be considered when IV boluses ofmethadone are given.

尽管在此次试验中，美沙酮并没有造成血流动力学不稳，但是当静脉给予单次大剂量美沙酮时应该考虑到有可能因为组胺释放而产生血流动力学方面的副作用。

METHODS: The model of LPS attack rats was established, and different doses of hydrocortisone were given to the rats.

建立大鼠LPS攻击模型，并给予不同剂量的激素，取血检测血浆ALT和AST，并观察肝脏HE染色的形态学改变。

Methods The milk volume, morphology of mammary gland, serum prolactin level and pituitary acidophil number in lactation rats and the growth improvement in suckling mice were observed after administrating various dosages of Maidang Rutong Granules to lactation rats by gastric gavage .

方法哺乳期大鼠灌胃给予不同剂量的麦当乳通颗粒后，观察其泌乳量、乳腺组织形态、血清泌乳素水平和垂体嗜酸性细胞数量的变化，以及对乳鼠生长的促进作用。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

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