结论

OBJECTIVE To design and develop a clinical pharmacokinetics and individual drug dosage regimens system CPKDP program for estimating individual pharmacokinetic parameters and optimizing individualizing dosage regimens using routine clinical data of plasma levels. METHODS According to the principle of population pharmacokinetics and Bayes" formula, CPKDP program was written with FOXPRO 2.6 and BORLAND C++ 3.1, and was run on 486 microcomputer with UCDOS 5.0. RESULTS CPKDP program was adapted for drugs with different characteristics of pharmacokinetics, and for single dose or multiple dose administration. Using 1 or 2 measured drug concentrations, individual patient"s pharmacokinetic parameters were estimated based on population-average pharm-acokinetic parameters. CONCLUSION CPKDP program is applied for estimating pharmacokinetic parameters and optimizing drug therapy in individual patients.

目的为利用临床常规监测的血药浓度数据估算病人的个体药动学参数，优化给药方案，设计、研制了临床药动学给药个体化系统CPKDP程序方法依据群体药动学原理及Bayes公式，CPKDP程序用FOXPRO 2.6和BORLAND C++ 3.1开发，在希望汉字系统UCDOS 5.0平台上运行结果CPKDP程序适用于具有不同药动学特征的多种药物，适用于不同给药途径的单剂量或多剂量给药在群体药动学参数的基础上，结合病人个体特征，以1，2个血药浓度作为反馈，即可拟合估算个体药动学参数，优化给药方案结论经初步应用，CPKDP程序是应用Bayes反馈法开展临床个体化给药工作非常实用的工具

uses the radio frequency below nose endoscope hemostatic, can make clear each bazoo path and nose top reach the effect to concealment the haemorrhage of place, effective and hemostatic.

结论采用鼻内窥镜下射频止血，能明确各鼻道及鼻顶等及效果隐蔽部位的出血，有效止血。

So it is no good to make business portfolio decision only depending on the conclusion of BCG matrix approach.

因此，不能单纯依据波士顿矩阵法的结论进行业务投资组合决策。

He would probably not be adverse to this further conclusion, since his goal is to show that "nature" decides the issue for us in the end.

他可能不会反对这个进一步的结论，因为他的目标就是指明'自然'是最终决定……

Be based on/upon Based on the results, a conclusion was made by us.

根据这次实验结果，我们得出了这个结论。

ConclusionThe P53 gene mutation was not related to IP and may be closely related to ID.

结论P53基因突变在IP中不表达，在ID中部分阳性表达。

Objective consideration of contemporary phenomena compels the conclusion that success or failure in competitive activities exhibits no tendency to be commensurate with innate capacity, but that a considerable element of the unpredictable must inevitably be taken into account.

对现实中诸多现象的客观观察使得我们不得不得出这样一个结论：竞争活动中的胜负并没有呈现出与人们内在能力的一致性。因此，我们不得不对相当大成分的不确定因素加以考虑。

It can be concluded that the effect of MSA seems to be consistent with the intended policy goal.

该研究的基本结论是，个人账户对城镇医疗保险制度的影响与预期的政策目标基本一致。

This would be different from others'opinions. It is a new discovery.

而这与前人的研究结论是不同的，是一个新的发现。

It was decided, as the result of a medical board, to invalid him, and he will be discharged from the army on 25th April.

因为医疗委员会的结论，已决定让他退役，他将于4月25日退伍。

And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时，论述了一体化管理体系构建中的几个主要问题，包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。