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结核杆菌

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Source of infection: patient who discharges bacillus tubercule.

传染源:主要是能够排出结核杆菌的患者。

In addition to air some of the Central Plains and some micro-organisms (non-pathogenic micro-organisms saprophytic, Bacillus, is Achromobacter, as well as a small number of Streptococcus actinomycetes, yeast and fungi, and so on), there may be from a human body More pathogenic micro-organisms such as Mycobacterium tuberculosis, diphtheria bacteria, Streptococcus, Staphylococcus aureus, meningococcal, influenza virus, measles virus, etc.

除大气中原有的一些微生物(非致病性的腐生微生物、芽胞杆菌属、无色杆菌属、细球菌属以及一些放线菌、酵母菌和真菌等)外,也可能存在来自人体的某些病原微生物(如结核杆菌、白喉杆菌、溶血性链球菌、金黄色葡萄球菌、脑膜炎球菌、感冒病毒、麻疹病毒等)成为空气传播疾病的病原。

Results: Amang 128 patients, 56 cases were diagnosed as pulmonary carcinoma (43.75%), of which 30 cases were squamous carcinoma (53.57%), 22 cases were adenocarcinoma (39.29%), 4 cases were small cell undifferentiated carcinoma (7.14%); 37 cases were bronchial pneumonia (28.91%), in which 30 cases were given brush sampling, bacterial culture of BALF, the detectable rate of pathogenic bacteria were 50%(15 cases) and 40%(12eases) respectively; 12 eases were pulmonary tuberculosis (9.38%), of which 3 eases (25%) had concurrent endobronchial tuberculosis, smear of brush biopsy and BALF found Mycobacterium tuberculosis were 11 eases (91.67%) and 5 eases (41.67%) respectively, 2 eases were diagnosed as caseous tubereulous granuloma (16.67%); 2 eases were idiopathic pulmonary fibrosis (1.56%), lease was lymphoma of long.

结果:128例患者确诊为肺癌56例(43.75%),其中鳞癌30例(53.57%),腺癌22例(39.29%),小细胞癌4例(7.14%);支气管肺部炎症病变37例(28.91%),其中30例经防污毛刷采样、支气管肺泡灌洗液行细菌学培养,病原菌的检出率分别为50%(15例)和40%(12例);肺结核12例(9.38%),其中合并支气管内膜结核3例(25%),刷检涂片和支气管肺泡灌洗液找到结核杆菌分别为11例(91.67%)和5例(41.67%),病理确诊为结核性乾酪样肉芽肿2例(16.67%);特发性肺间质纤维化2例(1.56%),肺淋巴瘤1例(0.78%)。

Debris necrosis of lymph node is not the specific changes of KD. In the tuberculosis of lymph node,① debris necrosis is obvious, but it tends to be caseous nercrosis;② histiocytes, macrophages and foam cells are hyperplasia in the necrotic area or lymph sinus, moreover, epithelioid cells can be found and they tend to be form granuloma;③ numbers of neutrophils infiltrate in the necrotic area;④ the etiologic assay of acid fast bacterium tuberculosis bacterium is positive;⑤ typical clinical manifestation is insufficient.

淋巴结碎屑性坏死并非KD特有病变,诊断KD需先除外有明显碎屑性坏死的淋巴结结核病,后者主要表现:①碎屑性坏死虽明显,但趋于干酪样坏死;②坏死区内或同时在淋巴窦内,组织细胞、巨噬细胞和泡沫细胞增生,并演变为上皮样细胞和趋于肉芽肿形成;③坏死灶内、外可有数量不等的中性粒细胞浸润;④抗酸杆菌/结核杆菌病原学检测阳性;⑤缺乏KD的典型临床过程。

Coli, Shigella sonnei s, Proteus, typhoid and vice Salmonella typhi, Pseudomonas aeruginosa, Vibrio cholerae and other enteric pathogens are effective; its ethanol extract on the number of gram-positive and-negative bacteria, and human-type Mycobacterium significant antibacterial activity; ebony decoction on in vitro to be sore dermatophytes, Epidermophyton floccosum, plaster-like pathogenic microorganisms in the skin of small spores of fungi

广谱抗菌:实验证明,乌梅水煎液对炭疽杆菌、白喉和类白喉杆菌、葡萄球菌、肺炎球菌等皆有抑制作用,对大肠杆菌、宋内氏痢疾杆菌、变形杆菌、伤寒和副伤寒杆菌、绿脓杆菌、霍乱弧菌等肠内致病菌也有效;其乙醇浸液对一些革兰阳性和阴性细菌,及人型结核杆菌均有显著抗菌作用;乌梅水煎液在试管内对须疮癣菌、絮状表皮癣菌、石膏样小芽孢菌等致病皮肤真菌有抑制作用

"Evidence supporting transplantation as the route of transmission ranges from circumstantial (ie, development of TB in the transplanted organ within a few months of transplantation) to well-established (ie, 2 recipients of a single donor's organs both developing disease through genotypically identical M tuberculosis , of which there have been 2 previous reports [4 prior recipients from 2 donors])," said Gregory Rose, MD, from the Division of Infectious Diseases, Ottawa Hospital, Ontario.

安大略渥太华医院感染疾病部门的Gregory Rose医师表示,证据支持器官移植作为疾病传播的路径从依情况而定的(例如在移植后数月后才发生TB)到根深蒂固的,例如两位受赠者同样接受一位捐赠者的器官,且都得到以基因型确认的分支结核杆菌,过去已经有两个报告(从两位捐赠者得到器官的四位受赠者)。

Taken together, the heterogonous boost combination provided superior protection by stronger CD(superscript 4+)(Th1) and CD(superscript 8+) T cell mediated immune response, which suggested that it will be a promising regimen for MTB vaccine development.

结果表明,DNA初发免疫、BCG加强免疫法能显著提高小鼠CD(上标 4+),CD(上标 8+)T细胞介导的免疫应答,增强小鼠抗结核杆菌感染能力,是提高结核病疫苗免疫效果的新途径。

Hydropericardium multiplicity,upright,large proportion lymphocyte, bacillus tuberculosis can be found

心包积液常大量,多为血性,淋巴细胞比例高,可找到结核杆菌

The range of organisms found is very wide and includes bacteria (Pseudomonas M. tuberculosis, E. coli), fungi (Aspergillus, Monilia, Cryptococcus). Viruses (Cytomegalo-Virus. Herpes zoster) and Pneumocystis carinii.

致病微生物的范围很广泛,包括细菌(假单胞菌属、结核杆菌,大肠杆菌),真菌(曲霉属、念珠菌属、隐球菌属),病毒及卡氏肺囊虫。

Therefore, there is an urgent need to develop simple, fast, and cost-effective methods to identify drug-resistance in mycobacteria.

因此,发展简便、快速、廉价检测结核杆菌耐药性的方法显得尤其迫切。

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