结核

ABSTRACT:Nine proteins encoded by Mycobacterium tuberculosis RD1 region are important protective antigens that become absent in long passaging of Mycobacterium tuberculosis. They only exist in pathogenic Mycobacteria and are absent in Bacille Calmette-Guerin and environmental Mycobacteria. With good immunogenicities, they may play an important role in the diagnosis and prevention of Mycobacterium tuberculosis.

RD1区编码的9个蛋白，是结核分枝杆菌在长期传代过程中丢失的重要保护性抗原，仅存在于致病性分枝杆菌中，在卡介苗及环境分枝杆菌中缺失；其有较强的免疫原性，在结核病的诊断中发挥重要作用。

At age 25 his elbows and knees became swollen and painful. He was admitted to a local hospital and found to hae lytic lesions in the mandible, claicles and patellae; bone biopsies were nondiagnostic and cultures were negatie for bacteria, fungus and TB. At age 27 he deeloped pain and restricted motion in the temporomandibular joints.

他17岁时出现背下部痛，晨僵，且体重减轻40磅。25岁时手肘和膝盖肿胀疼痛，遂于当地医院住院，发现下颌骨、锁骨和膝盖骨有溶解性病损，骨活检不能诊断，骨培养也未发现细菌、真菌和结核。27岁时，他的颞颌关节出现疼痛，且转动受限。29岁时他因进食困难而来约翰斯。

Pharmacies could be useful and play a role in TB case detection.

药店能够在结核病人的发现工作中起到较好的作用。

This indicates that the recombined tuberculosis vaccines can induce higher cell immunity level than BCG.

这说明本发明的重组结核疫苗可以诱导较BCG高的细胞免疫水平。

Methods: Sixteen matched pairs of elbalmed adult cadaveric femora(age from 50 ～ 59) were obtained and skeletonized.

取成年男性防腐股骨标本16对，年龄在50～59岁，去除软组织，透视及骨密度测量无风湿、结核肿瘤、解剖变异及骨质疏松，且左右对称性良好。

Results All the patients showed sputum negative conversion and were cured without anastomotic fistulae, stenoses and other complications.

结果46例结核性支气管狭窄患者得到治愈，无残端和吻合口瘘；痰菌全部转阴；无狭窄复发。

Up to now however, there has been no evidence that PET leads to improved management of patients in routine clinical practice. We did a randomised controlled trial in patients with suspected non-small-cell lung cancer, who were scheduled for surgery after conventional workup, to test whether PET with 18FDG reduces number of futile thoracotomies.

首先，在原发瘤的评估方面，其作用目前仅限于对单发肺内结节的良恶性鉴别，并且阳性预测值相对较低，在肿瘤可切除性评估方面的作用远逊于CT；更何况肺内良性肿瘤也需要手术切除，而那些不需要手术的病灶，比如活动性结核瘤及炎性肿物，PET 的假阳性率又太高。

Tuberculosis with Real time-FQ-PCR, acid-fast staining and culture had been done as contrast control at the same time.

目的：探讨FQ-PCR技术在检测临床标本中结核分枝杆菌的应用价值。

Results the positive rates and specificity of fluorescence quantitative pcr, acid-fast stain,were100% and 30% respectively.

结果 荧光定量 pcr、抗酸染色法检测结核分枝杆菌的特异性分别为100%、30%。

Methods: Several results obtained by MB/BacT system were analyzed, including the recovery rate of acid-fast bacilli, the contamination rate and the mean time for positive reporting from clinical specimens.

通过对仪器检出报阳时间、阳性率、污染率及药敏结果的分析，了解仪器的效能及结核分枝杆菌的耐药情况。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。