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HBsAg positive patients were more likely to have liver damage in antituberculosis treatment.

HBsAg阳性患者在抗结核治疗中肝功能更轻易受损害。

The incidence rate of liver injury for the first-line antituberculosis therapy is about 20%.

目前已知,第一线抗结核药物治疗期间肝损伤之发生率约为20%。

All the patients received a full course of antituberculosis treatment.

全部患者确诊后均转至结核病院进行治疗。

Isoniazid is one of the most important antituberculosis drugs. However, the resistant rate to INH is increasing very fast in recent years. The mechanism of M.

异烟肼是抗结核治疗中最重要的一线药物之一,也是目前耐药现象上升最快和最为严重的药物。

Liver injury is the most common side effect during the first-line antituberculosis therapy.

肝损伤是第一线抗结核药物治疗期间最常见的副作用。

Patients were randomly assigned either dexamethasone (n=24) or placebo (n=19) and receied 9 months of treatment with standard first-line antituberculosis drugs.

患者被随机分成两组,一组给予地塞米松(n=24),一组给予安慰剂(n=19),同时接受9个月的一线标准抗结核药治疗。

Early diagnosis of the disease and rapid identification of resistance to primary antituberculosis agents are essential for efficient treatment and control of multidrug-resistant strains.

因此,对主要抗结核药物如利福平的耐药性快速检测对于有效治疗结核病和控制耐多药株的流行是必不可少的。

Results All cases were misdiagnosed before operation and were cured with antituberculosis drugs after operation.

结果全部病例术前均误诊,术后病检证实,抗结核治疗治愈。

Results Liver injury induced by antituberculosis drug occurred more frequently in patients with risk factors and mostly occurred 1~8 weeks after the initial of chemotherapy.

结果 抗结核药所致肝损伤多见于具有危险因素的患者,多发生于用药的第18周。

ConclusionThe protective effects of baicalin on hepatic injury induced by antituberculosis drugs may be related to inhibit TNF-α protein expression.

结论黄芩苷对抗结核药物肝损伤的保护作用可能与抑制TNF-α蛋白表达有关。

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