结核

Results The concentration of IL-18 in tubercular pleural effusion group was (1200.34±530.25) pg/ml, while that of the malignant pleural effusion group was (240.40±80.49) pg/ml, the former was significantly higher than the latter (P.01); The analytic result of ROC curve showed that 360 pg/ml IL-18 could be seen as the critical value for diagnosis of the tubercular pleural effusion, whose sensitivity and specificity respectively was 89.2% and 93.5%.

结果 结核性胸腔积液组IL-18的浓度为(1200.34±530.25)pg/ml，恶性胸腔积液组IL-18的浓度为(240.40±80.49)pg/ml，结核性胸腔积液组IL-18的浓度显著高于恶性胸腔积液组(P.01)；ROC曲线分析结果显示IL-18以360pg/ml为诊断结核性胸腔积液的临界值，其敏感度和特异度分别是89.2%和93.5%。

It is recommended that the L-forms should be noticed during the treatment with the antituberculosis drugs and combination treatment with antituberculous drugs to which the L-forms were susceptible, is also very important.

根据结核分支杆菌L型的药物敏感性特点，建议在使用抗结核药物治疗中须注意其L型的形成和联合使用结核分支杆菌L型敏感的抗菌药物进行治疗。

In this review, we presented novel agents with potential for the treatment of tuberculosis, which through natural product screening, design and synthesis of new drugs and structure modification of antituberculous agents; we also described advance in molecular biology of tuberculosis and the development of antituberculous targets.

文中综述了近年来通过天然物筛选、新药设计合成以及对现有抗结核药物的再修饰等途径，发现的一些有抗结核活性的化合物，以及结核杆菌分子生物学和抗结核治疗靶点的研究进展。

Sleep is restless and spiritual dispirited in 2 cases (3.6%), the chest X-ray normal position piece examination lungs tuberculosis pathological change in 52 cases (92.9%), the normal position piece examination does not have the obvious tuberculosis pathological change, but to lean the posit

睡眠不安、精神不振2例（占3.6%）胸部X线正位片检查肺部结核病变52例（占92.9%），正位片检查无明显结核病变而侧位片及胸部CT显示肺内及肺门淋巴结结核病变4例（占7.1%），结核菌素试验强阳性27例（占48.2%），痰查结核菌阳性3例（占5.4%），淋巴结活检 5例（占8.9%）。26例治疗9个月后病变完全吸收，29例6个月后病变完全吸收， 1例因药物肝炎不能顺利完成治疗。

Sleep is restless and spiritual dispirited in 2 cases (3.6%), the chest X-ray normal position piece examination lungs tuberculosis pathological change in 52 cases (92.9%), the normal position piece examination does not have the obvious tuberculosis pathological change, but to lean the position piece and in the chest CT demonstration lung and the lung hilus lymph node tuberculosis pathological change 4 cases (7.1%), the PPD test was strong masculine 27 cases (48.2%), the phlegm looks for the tuberculosis bacterium masculine gender 3cases (5.4%), the lymph node biopsy 5 cases (8.9%). 26 cases treated for 9 months the pathological change to absorb completely, 29 cases 6 months the pathological change absorbs completely. Because the medicine liver is poisoned 1 cases cannot smoothly complete the treatment.

睡眠不安、精神不振2例（占3.6%）胸部X线正位片检查肺部结核病变52例（占92.9%），正位片检查无明显结核病变而侧位片及胸部CT显示肺内及肺门淋巴结结核病变4例（占7.1%），结核菌素试验强阳性27例（占48.2%），痰查结核菌阳性3例（占5.4%），淋巴结活检 5例（占8.9%）。26例治疗9个月后病变完全吸收，29例6个月后病变完全吸收， 1例因药物肝炎不能顺利完成治疗。

After routine antituberculosis chemotherapy, the patients were treated by dead bone erasion and tuberculose focus removal of abscess, dead bone, granulation tissue and cheese-like substance, intervertebral body fusion with bone graft and Ventrofix system.

经术前正规抗结核药物化疗后行病椎死骨刮除，周边脓肿、死骨、肉芽组织及干酪样物质等结核病灶清除，椎间大块自体骨植骨或钛网植入自体骨粒植骨，一期行前路内固定术，术后继续抗结核治疗1～1.5年。

In this paper, much energy has been placed on phosphate concretion re search which host in black shales of Dou Shantuo Fm. and Nu Titang Fm、 Research contents include mineralogy, petrology and geochemistry character istics of phosphate concretions. Element distributive characteristics are ana lysed using Synchrotron Radiation techniques. Additionally, sulfur isotopes of francolite and their significance are discussed in this paper. The results are as following

本文开展了晚震旦世陡山沱组以及早寒武世牛蹄塘组两套黑色页岩中磷结核的研究，对产于这两套黑色页岩中磷结核的矿物组成、地球化学等方面开展了研究，首次运用了同步幅射X-荧光探针对结核内元素的分析特征进行了分析，同时还测定了磷的硫同位素并讨论了其意义，所得出的结果简述如下

The first aim of this study is to clarify whether that polymorphisms of the genes that encode these enzymes associates with the TB drugs-induced adverse reactions. Furthermore, since tuberculosis patients are always administrated with multiple TB drugs, it is hard to distinguish which TB drug caused these adverse reactions.

本研究从结核药物过敏病患代谢酵素基因多型性方面探讨与结核药物过敏反应发生的相关性；此外，由於结核病患通常同时接受多种结核药物的治疗，导致难以判断是其中何种药物引起不良反应，本研究另一目标即为建立一T细胞体外培养系统，用於判断何种药物引起不良反应的产生。

Results Irritative symptoms (78%) and gross hematuria (36%) were the most common symptoms encountered in these patients.

结果尿路刺激症状和血尿为最常见症状，分别为78％和36％。24小时尿抗酸杆菌和尿结核PCR的阳性率分别为25％和40％，IVU，逆行尿路造影及CT的诊断符合率分别为38％，63％和44％。33例患者接受了肾及部分输尿管切除术，肾上盏结核病灶清除术1例，对侧输尿管膀胱吻合术1例及肾穿刺造瘘术1例。1例患者并发血行播散型结核死亡。

Objectives To investigate the mechanism of generation of L-form of M.tuberculosis and its significance on the development,diagnosis and treatment of tuberculosis. Methods M. tuberculosis was inoculated into the non-high osmotic medium with rifampin, isoniazid or ethambutol and then the L-form was observed by microscopy daily.

目的 观察常用抗结核药物对结核分支杆菌L型的诱导作用以及结核分支杆菌L型在非高渗透压培养基内的某些特性及其抗菌药物敏感性，探讨结核分支杆菌L型形成的机制及其在结核病的发生、诊断及治疗上的意义。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。