结果

Results The pathological diagnosis of cervical conization by LEEP were consistent with that of multi-point biopsy by colposcope in 155 patients (45.45%), downgraded in 135 patients (39.59%),upgraded in 51 patients (14.96%), including 14 cases of early invasive cervical cancer (4.11%).

结果 LEEP刀环形电切术病理检查结果和阴道镜多点活检的病理结果相同的有155例(45.45%)，减轻的有135例(39.59%)，加重的有51例(14.96%)，其中早期浸润癌14例(占4.11%)。。

The study showed the recombinant wt/mCREG protein depressed the VSMC proliferation depending on dose and the optimal concentration was 400nM;2biologic function of CREG protein and the membrance receptor mechanism:①effect on VSMC migration: the wound healing experiment showed the OB2 cells migration was slower significantly after added wt/mCREG(400Nm) in supernatant. The HITASY cells migration were very slowly and no remarkable change. The gelatinase digestion and Western blot analysis showed the matrix metalloproteinase was decreased and TIMPs was increased;②effect on differentiation: after added wt/mCREG(400nM), the expression of myocardin, SMα-actin, MHC and caldesmin were increased and that of LM-1 and FN were decreased in OB2 cells. These effects were more significant when adding wtCREG.;③effect on VSMC proliferation: Cell cycle assay and BrDU stain showed: after added the wtCREG and mCREG protein, the ratio of cell in G0/G1 phase increased to 0.5773 and 0.5572 from 0.5308 respectively in OB2 group, which increased to 0.7369 and 0.7034 respectively from 0.6297 in HITASY group;3Role of M6P/IGF2R in CREG biologic function:①ELISA and co-immunoprecipitation showed the wt/mCREG binding to M6P/IGF2R directly.②antibody blocking test: when the anti-IGF2R was added to medium at the same time with wt/mCREG at different concentration(2μg/mL、4μg/mL、8μg/mL),the effects of CREG protein which depressing proliferation, migration, secretion and promoting differentiation were blocked, which had the positive correlation to the concentration of added anti body. The studies showed two combinant CREG promoted VSMC switch to differentiation phaenotype, at the same time, depress VSMC proliferation, migration and secreting extracellular matrix.

上述实验结果证实：两种重组CREG蛋白对VSMC增殖均有剂量依赖性的抑制作用，并且相同浓度的糖基化的CREG蛋白对细胞增殖的抑制效应更为显著，最佳效应浓度为400nM；2两种重组CREG蛋白添加后对HITASY和OB2细胞生物学行为的影响：①CREG蛋白对VSMC迁移的影响：刮伤实验发现，加入最佳效应浓度的wtCREG和mCREG蛋白24h后，OB2组迁移能力下降，HITASY组无明显变化；细胞外基质金属蛋白酶-2，9(Matrix metallo-proteinase 2，9，MMP2 ，9)明胶酶电泳检测和Western blot检测结果证实，两种CREG蛋白均可以使OB2细胞合成细胞外基质MMP2，9减少，而组织金属蛋白酶抑制物(Tissue Inhibitors of Metalloproteinases，TIMPs)增加；②CREG蛋白对VSMC分化的影响：加入400nM的wtCREG和mCREG蛋白12h后，OB2细胞myocardin、SMα-actin、MHC、caldesmin表达增加，LM-1、FN表达减少；③流式细胞仪分析细胞周期和BrDU染色分析证实，加入400nM的wtCREG和mCREG蛋白后，OB2组G0/G1期细胞由0.5308分别增加至0.5773和0.5572，HITASY组G0/G1期细胞由0.6297分别增加至0.7369和0.7034；3M6P/IGF2R在重组CREG蛋白的生物学功能中的调控作用：①免疫共沉淀和免疫荧光双染色分析结果显示，CREG蛋白与M6P/IGF2R存在直接结合；②应用抗体阻断实验：将不同浓度的anti- M6P/IGF2R(2、4、8μg /mL)与两种CREG蛋白同时加入培养液中，CREG蛋白抑制VSMC增值、迁移和合成细胞外基质、促进分化的效应减弱，而且与加入anti- M6P/IGF2R浓度正相关。

For purposes of this document, the term OOS results includes all suspect results that fall outside the specifications or acceptance criteria established in new drug applications, official compendia, or by the manufacturer.

本行业指南反应了FDA关于如何评估怀疑的或OOS检验结果的现行想法，本指南的目的，OOS结果包括超出了新药申请材料、法定标准、生产商建立的可接受标准或规格的所有可疑的结果。

There were some differences existing in the two cluster results revealed by RAPD and SRAP markers,they were as follows:compared to that of RAPD,the result of SRAP could more comfortably manifest the kinship、geographical origin、tree forms and so on,and also was more conformant to the traditional classification.

基于两种标记的聚类结果存在一定的差异，SRAP聚类结果能较好地体现供试品种的亲缘关系、地域特性和树型特点，与传统的基于形态特征建立的分类结果比较一致。

The result indicates that conicoid anti error is smaller than that of plane and three cubed anti error fitting model, but the validity of the model doesn't necessarily have relationship with model steps.

结果 二次曲面抗差的结果要好于相关平面与三次曲面抗差的结果精度，并非抗差模型阶次越高有效性越高。

In briefly, negligent coprincipal is one joint criminal pattern in which more than two doers disobey joint attention obligation. The constitution of negligent coprincipal : Firstly, number of subject of crime should be above two and they should possess criminal responsibility. Secondly, they should have joint attention obligation to avoid consequence.

过失共同正犯是指二人以上的行为人在意思联络支配下，相互利用、相互补充他人行为，合作实施具有导致危害结果发生的现实危险性的行为，从而负有防止危害结果发生的共同注意义务，但是由于全体行为人共同的不注意，以致危害结果发生的共同犯罪形态。

The interpretation results of pilot test area are identical with that of coring well data.

运用所建立的解释方法对开发试验区资料进行了解释，解释结果与取心井资料的解释结果基本一致，且解释结果已应用于后续的开发调整。

The increase in either OCDAS or AAS scores associated with provocation was statistically significant (P＜0.01). A statistically significant increase (P＜0.05) in rCBV during the OCD symptomatic state versus the control state was found in the right inferiofrontal cortex, postcentral cortex, angular cortex, and bilateral orbitofrontal cortices, cuneus cortices, heads of caudate neucli, thalami and amygdalae.

结果 静息期和诱发期的强迫症状评分结果分别是1.00±0.33和6.65±0.71，有显著性差异（P＜0.01）；静息期和诱发期的焦虑症状评分结果分别是1.20±0.42和2.75±0.42，也有显著性差异（P＜0.01）；与静息期相比，右侧额下回、中央后回、角回、双侧眶额部、楔叶皮质及双侧尾状核头、丘脑、杏仁核rCBV在症状诱发期显著增加（P＜0.05）。

Four methods for evaluating circularity error. least-squares method for evaluating cylindricity error. 3.Using language of VC++, a software of form error evaluating is developed. Module structure is adopt in this software and every element has one module.

用VC++开发了形状误差的评定软件，软件采用功能模块结构，每种元素均设计为一个独立的模块，为使评定结果更加直观，采用OpenGL对处理的结果进行了可视化处理，结果图形可以随意转动和缩放，以方便观察。

The levels of SOD and CAT significantly increased and MDA decreased in bifidobacterium group compared to radition damage group.Electronic microgragh of spine neurocyte and neurogliocyte showed that cytoplasm,cytoblast and plastiosome were significantly engorged ,and neurogliocyte apoptosised in earlier period. TLR2mRNA increased in C group compared to B group by RT-PCR. Cytochrome C in kidney increased in C group compared to B group, but bcl-2,NF-Кb decreased. Conclusions : Enteroclysm is better compared to intragastric administration.

双歧杆菌处理组肝组织中SOD和CAT水平明显高于放射损伤组(P.01)，同时MDA明显低于放射损伤组(P.01)；电镜结果显示：放射损伤组与双歧处理组的细胞浆、细胞核和线粒体均明显肿胀，双歧处理组同时具有早期凋亡现象；RT-PCR结果显示：双歧处理组TLR2mRNA的表达明显高于放射损伤组；免疫组化结果显示，双歧处理组Cytochrome C的表达明显优于放射损伤组，而NF-кBp65和bcl-2则相反。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！