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结构破坏

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AITL, diagnosed based on lymph-node biopsy, was characterized by damage to normal structure of lymphonodus, proliferation of immunoblastic cells, and arborescent supervascularization. Immunophenotypes were observed in mature peripheral T-cell lymphoma. CVP regimen was the most commonly used chemotherapy. Fifty-eight percent of patients had a good initial response to chemotherapy. The 3-year survival rate was 25%, with a median survival time of 20 months.

确诊依据淋巴结活检,病理组织学呈淋巴结结构破坏,免疫母细胞增生,树枝状血管增生的特点,免疫表型全部为成熟外周T细胞性。12例均用CVP为主的方案化疗,总有效率58%。3年生存率为25%,全组中位生存20个月。

The results showed as follows: the structural properties of damaged soils were spoiled with lack of waterstable aggregates and big pores, and clayish texture; the function of nutrient and water holding were also weakened. The primary countermeasures for rehabilitating damaged soils were brought forwar

结果表明:道路毁损土地的土壤团聚体的水稳性差、大孔隙较少、土壤结构破坏,土体紧实,质地粘重,土壤的通透性、保肥保水功能弱等问题,并初步提出了一些毁损土地退化修复利用的措施。

When they combined with antibodies and deposited on the lamella lucida of BMZ, the classical pathway of complement was activated, and induced production of many kinds of mediators of inflammation, resulting in the disorganization of half desmosome and forming hydroa under the epidermis.

抗原抗体反应形成的免疫复合物沉积在基底膜带透明板部位,后者激活补体经典途径,诱导多种炎症介质的产生,导致半桥粒结构破坏并形成表皮下水疱。

The cell processes showed up from the edge of explants and neuroglial cell migration was observed at the early stage.

培养早期上丘脑组织块边缘出现细胞突起,胶质细胞迁移,随着培养时间延长,细胞出现凋亡,组织结构破坏

It is evident that the plerocercoids parasitize mainly in the subcutaneous tissues and muscles of mice, and mice experimentally infected with plerocercoids show different degree of histopathological changes.

小鼠感染裂头蚴后,多组织器官有裂头蚴寄生,其中以皮下肌肉处多见。裂头蚴寄生可引起组织不同程度的增生、变性、坏死,组织结构破坏及大量炎症细胞浸润等病理变化。

Results Revealed the pathognomonic changes:the mantle cell zone were remarkably wide,but germinal center became small,the nucleous form of it were irregular,and the structural changes of lymph node also slight.

结果 发现其以淋巴套细胞显著增宽而生发中心明显缩小,瘤细胞小,核形轻度不规则和原有淋巴结结构破坏较轻为其形态特征。

Soil ecological degradation can be defined as the process and phenomenon of a series of deterioration of soil ecological environment such as structural destruction and functional recession of soil ecosystem, decrease of soil biodiversity and productivity, dcsertification, drought, hardness, acidification and salination of soils, deficit and unbalance of soil nutrients, and loss of soil and water, resulting from human activities and adverse natural environmental conditions.

土壤生态退化是指由于人类活动及恶劣的自然环境条件作用或二者共同作用下造成的土壤生态系统结构破坏、系统功能衰退、土壤生物多样性减少、土壤生产力下降以及土壤荒漠化、干旱化、板结化、酸化、盐碱化和养分亏缺与失衡等一系列土壤生态环境恶化的过程和现象。

Through simulation of the real process of thomcolumbar burst fracture and use of modem dynamics techniques, the present study was (1) to investigate the kinetic relationship between structural damage and impact energy absorption and dynamics mechanism of thoracolumbar burst fracture by quantitative analysis of various injured segments;(2) to explore the instability mechanism of L1 vertebral burst fracture and its injury threshold by three-dimensional analysis of the injured segment with stereophotogrammetry in combination of transient physical parameters, anatomy and image;(3) to explore the corresponding relationships between impact energy, geometry parameters and biomechanics by geometry and biomechanical analysis of thoracolumbar burst fracture, which may provide an objective standard for evaluation of spinal injury severity and experimental evidence for adoption of biomechanical treatment in clinic;(4) to evaluate the fixation effect of different instruments and the effect of intervertebral bone graft on segment fixation by analysis of the threedimensional stability of different internal fixation instruments and their decompression of the spinal canal, which may provide experimental evidence for therapeutical selection for thoracolumbar burst fracture in future; and finally to investigate the effect of various instrument fixation on dynamical characteristics by comparison and quantitative analysis of frequency and amplitude responses, which may provide certain theories and experimental evidence for application of vibration test to judge the stability of the spine.

本研究从胸腰段脊柱爆裂骨折发生的实际过程出发,以现代动力学检测及计算机多通道高性能数据采集分析系统等高新技术为基础,实时量化分析损伤节段的工程参数,揭示了结构破坏与能量吸收的变化规律,探讨了胸腰段脊柱爆裂骨折的瞬态损伤机制;利用三维立体摄像技术,对不同损伤程度的节段进行三维运动分析,结合瞬态物理参数、影像学和病理解剖,明确了〓椎体爆裂骨折的失稳机制及损伤阈值;通过对胸腰椎爆裂骨折的几何学变化及生物力学分析,明确了撞击能量与几何参数、几何参数与生物力学的相应关系,为评判脊柱损伤程度提供了客观标准,为治疗中采取适宜的生物力学方法提供了实验依据;通过对比分析不同内固定器械的三维稳定性和对椎管的减压作用,评价不同器械的复位固定作用,同时比较椎体间植骨对节段固定作用的影响,为今后临床胸腰段脊柱爆裂骨折的治疗选择提供依据;利用振动测试与分析技术,比较及量化分析了不同致伤状况的频幅响应特征,比较分析了各种器械固定对动力学特性的影响,为今后临床建立基于振动测试与分析技术判断脊柱稳定性的诊断方法,提供了一定的理论和实验依据。

Cartilaginous destruction of the ear, nose, peripheral joints, larynx, and tracheobronchial tree may develop as a result of this process .

复发性多软骨炎是一种罕见的,以具有退变、结构破坏、纤维化的软骨炎症反复发作为特征的自身免疫综合征。

Based on the theories of rheology, Non-Newtonian Fluid Mechanics, petroleum chemistry, crystallography and pipeline technology etc. and sampling Huabei crudes, experimental indexes and programmes are drew out, integrating the oil properties and parameter analysis; in terms of the macro analysis of continuum mechanics, substantial experiments are conducted with HAAKE RS600 rotational rheometer and the rheological equation as well as the viscosity-temperature equation are further developed with tested rhrogramme and viscosity-temperature curve, respectively. Beased on the researches on thixotropic mechanism and thixotropy fluid property, hysteresis loop curve, structure failure and viscosity build-up curve as well as shear stress decrement curve for one type oil are first present in this paper. According to the theoretical researches and testing results, a novel thixotropy equation with τ=τ_∞e~ pattern, which is of hi-accuracy, few parameter and simplicity, is developed. Considering the influence of various parameters on rheological behaviour, depressant adding condition is optimized and experimental evaluation on BEM-5P is conducted, which further unrip its mechanism on the Huabei crude. A corresponding viable pipe transportion programmel is also recommended.

本文基于原油流变学、非牛顿流体力学、石油化学、结晶学、原油管输工艺学等理论,以华北原油为研究对象,结合原油物性及实验影响因素分析,制定出实验研究的评价指标及实验方案;从连续介质力学宏观分析的角度,利用HAAKE RS600高端旋转流变仪开展了大量的室内实验,并运用微观研究方法,测定了油样的流变曲线和粘温曲线,建立了流变方程和粘温方程;通过对触变性机理和触变性流体特征的研究,首次对华北原油测定出滞回环曲线、结构破坏与恢复粘时曲线、剪切应力裂降过程曲线,并在理论研究和实验结果的基础之上,建立了能定量描述含蜡原油剪切应力裂降过程的新型三参数触变模式τ=τ_∞e~b/(t+c,该模型具有精度高、参数少、实验简便且适用性强的特点;通过对含蜡原油流变性的影响因素理论研究,开展了加剂条件优选及BEM-5P降凝剂室内评价实验,进一步揭示了降凝剂对华北原油作用机理,在此基础之上,提出了华北原油管输的可行性方案。

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