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In this paper, the stable Au complexes are classified according to the coordination atoms and their structural characteristics. The recent development of the researches on the antitumor activity of Au complexes including the structure-activity relationships, biological targets and the mechanisms of action are reviewed. The structure of the coordination ligand and the leaving group have great impact on the in vitro cytotoxicity of the Au complex. Many physical and biological methods are introduced to study the interaction between the Au complexe and the suspected bio-target, such as DNA, protein, mitochondrion, thio-containing biomolecules, etc. The interaction modes (intercalating, electrostatic interaction, covalent bonding, etc.) are focused to illustrate the reason for the antitumor activity of Au complexes.

本文按配位原子的不同总结了稳定三价金配合物的结构特征,按其生物活性的构效关系、生物靶点和作用机制综述了三价金配合物抗肿瘤活性研究的最新成果:配体的结构特点以及离去基团对三价金配合物的体外细胞毒性影响较大;介绍了用于检测三价金配合物与可能的生物靶分子之间相互作用的多种物理和生物学方法,重点关注了相互作用的模式,如嵌入/静电吸引/共价结合等,并解释了三价金配合物抗肿瘤活性的原因。

Advancement in research on composites with interpenetrating networks ;2. In this paper,research status at home and abroad on manufacturing techniques of composites with interpenetrating networks and their preforms were summarized,with focus on the special feature of every one.

网络互穿结构复合材料的基体与增强相在整个材料中形成各自的三维连续网络并且互相缠绕,该结构可充分发挥各组成相各自的优势,以获得最佳的综合性能,它已成为最新的研究热点。

The basolateral M cell surface is invaginated to form an intracellular central pocket into and out of which lymphocytes and macrophages.

M细胞是一种特化的上皮细胞,多分布于Peyer's结圆顶区的周边,FAE的顶端未见M细胞;其结构有别于相邻的肠上皮细胞,表面没有长而整齐的微绒毛,取而代之的是粗而短的微皱褶,胞质内终末网不发达,溶酶体较少,基底膜向顶部穹隆状突起,形成一&口袋&样结构,其中含有多个免疫活性细胞。

Unfortunately,the numerating model used in such method is quite different from the actual instance,,and the constraints are too simple,the effects of the side load,elastic modular of the stone body of the foundation and the compatible structural deformation are not involved in. Due to the asymmetry of the spatial load,it is quite different between the analysis results and the test data.

这种集中计算方法力学模型的建立与结构的实际受力情况出入较大,且对边界条件考虑过于简单,对边荷载的影响、基础岩体弹模的影响及结构本身变形协调一致等均未能一并考虑,对于空间受力不对称的状况,作为二维问题分析时计算结果与应力测试结果出入较大。

On the optical emission part, I utilized Photoluminescence to investigate the emission wavelength. In the first section of my experiments, Indium-OxyNitride nanoparticles, they are octahedrons suggested to be formed via the VS mechanism dispersed on the Silicon substrate, ranging from 50 nm to 1 um in size grown from 600 degrees to 900 degrees in Celsius. The composition is also verified by the EDS apparently. The PL shows the emission wavelength spans the whole red region.

在第一部分的氧化氮铟奈米颗粒中,奈米颗粒推测是以VS的成长机制形成的八面体结构,以成长温度在摄氏600度至900度形成各个尺寸从50奈米至1微米间的奈米颗粒,并可在能量散布光谱中,验证此奈米结构的存在成分,并在光激发萤光光谱中,可以看出此奈米颗粒的发光范围可以涵盖整个红光波段。

The crystal structures have been determined by X-ray diffraction method, which show that the new complex [Co2-Co(2)(0H2)s] belongs to the bridging binuclear complex and the system of monoclinic with space group P211~,unit cell parameters a8.3850(10)A, b=27.386(4) A, c=9.610(2) A,~=98.280(10)~,V=2 183.8(6) A3 , Z=4, Dc=l.746Mg/m3,~i =l.597mm, F(000)=1168, Final R=O.0253 and wR=O.0610 S1.009 ,The two Co2~ are in distorted octahedrons. The part of [2Co] possess an approximate D2d symmetry, while the part of [OCo(2)(0H2)5] has an approximate C2 symmetry.

结构分析表明配合物(1)[Co1,(DPC2-Co(2)(OH2)5]是一个未见报导的桥联双核配合物,属单斜晶系,空间群为P2_1/c,晶胞参数:a=8.3850(10)A,b=27.386(4)A,c=9.610(2)A,β=98.280(10)A,V=2183.8(6)A~3,Dc=1.746Mg/m3,Z=4,μ=1.597mm-1,F(000)=1168,结构偏离因子R=0.0253和ωR=0.0610,吻合因子S=1.009,Co_(1)和Co_(2)的配位多面体皆为扭曲正八面体,[_2Co_(1)]部分具有近似D_(2d)对称性,[OCo(2)(OH_2)5]部分具有近似C_2对称性。

However,it has remained elusive as to whether CENP-E physically interacts with SEPT and how this interaction orchestrates chromosome segregation in mitosis.

Septin属于一类保守的细胞骨架蛋白质家族,它们具有类似的结构特征,septin在多种生物体内均可以形成异源多聚体的纤维状结构。

In addition,"water" concentrations of inclusions rutiles are higher than intergranular ones, and the rutiles from fresh eclogites hold more "water" than those from retrograded eclogites, implying that the retrograded fluid might not be derived mainly from release of structural hydroxyl during exhumation.

不同赋存状态金红石结构水含量的对比研究显示,粒间颗粒高于包裹体者,退变质榴辉岩略高于新鲜榴辉岩者,表明退变质流体可能并不主要来源于结构水的减压释放。

The double-towe-connected structure without enlarged base which is symmetrized in X and Y axises is one simple sort of MTCS. It is formed by tow towers and one or more connecting units which satisfy special functions and architecture demand, such as several spatial corridors.

不设置底盘、双轴对称的双塔楼连体高层建筑是多塔楼连体高层建筑中较为简单的一类,其体型是采用两个塔楼作为主体结构,塔楼间由于功能或造型要求通过一个或多个连接体相互连接而形成的一种复杂结构体系。

Methods Four transducers were set in head, oral cavity, larynx and chest cavity, respectively, recording the characteristics of spectral energy and distribution among 63 singers when pronouncing/a/ with low, medium, high tonalities respectively.

结论歌唱发声时的共振系统并非一个统一的共振频率,而是根据发声腔体的形状、共鸣位置及组织结构的不同而各异:各声部的特征丰兽与声带的自然结构、其振系缔的善异及喉内各肌。

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推荐网络例句

Others availed themselves of the throngs which attended the sacred festivals to indulge in immoderate enjoyment and tumultuous revelry.

其他人利用自己的throngs出席神圣的节日,以沉迷于immoderate享受和动荡不定的狂欢。

I'll go into the matter.

我会调查这事的。

At distance, Bulwer's Petrel appears to be uniform black.

在远距离之下,穴鸟呈现一致的黑色。