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Electrospray ionization mass spectrometry combined with multipletandem mass spectrometry has been applied for simultaneously determininglipo-alkaloids from the aconite tubers.

把电喷雾质谱和多级串联质谱(〓,n=2-10)结合用以分析附子中脂类生物碱的成分。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活,ICAM-1表达升高,与被激活的PMN表面表达的LFA-1相结合,"PMN-EC"相互作用加剧,一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍;另一方面粘附的PMN过度吞噬或激活,当白细胞吞噬的颗粒不能被封闭隔离,连同细胞内的酶被释放出来,其中的PMN-elastase能够降解细胞基质中各种成分,水解多种蛋白,加重胰腺的毛细血管内皮细胞和腺泡的损伤;释放的溶酶体酶使组织蛋白水解,产生的不饱和脂肪酸引发脂质过氧化方应,破坏细胞膜的结构和功能;释放的炎性细胞因子,激发其他的免疫细胞的功能,导致进一步的组织损伤和坏死,加重SAP的病理损伤,最终导致休克、脓毒血症及多器官功能障碍等严重后果。

The presence of REE tetrad effects in apatites and whole rocks of S-type granites has been reported by Sha and Chappell (1999) and Zhao et al.(1999), respectively. The REE tetrad effect in minerals, such as apatite, spessartite, beryl, alkali feldspar and spodumene, from all zones of Altay No. 3 pegmatite has been found remarkable, and the fractionations among isovalent incompatible elements in these minerals are also significant. This paper puts forward that the REE tetrad effect is one of the basic features of peraluminous melts and the origin of REE tetrad effect might be probably related to some processes prior to the formation of pegmatite magma. The immiscibile liquid separation between silicate melt and hydrosaline melt may be responsible for it.

由于阿尔泰3号伟晶岩脉各带磷灰石以及与其共生的石榴石、绿柱石、碱性长石、锂辉石矿物均存在明显的稀土"四重效应"以及相同电价、相似离子半径的不相容元素间存在显著的分异,并结合最近赵振华等(1999)和Sha and Chappell(1999)报道S型花岗岩全岩和单矿物(磷灰石、独居石、长石、黄玉等)均存在稀土"四重效应"这一现象,本文研究提出,稀土"四重效应"是富挥发分过铝质岩浆体系的一个基本特征,其机制既不可能由含稀土的副矿物早期结晶引起残余熔体相中REE含量变化的结果,也不能定性地归因于流体相与熔体相相互作用过程中稀土元素在流体/熔体之间分异的结果,而很可能与伟晶岩岩浆形成之前某些过程密切相关,S型花岗岩岩浆在液相线以上存在硅酸盐熔体与高盐熔体的不混溶液相分离有可能是过铝质岩浆体系产生稀土"四重效应"的主要原因。

Result:The monoclonal antibody H12 against human glioma which the hybridizing cell secretions can consociate specifically with human glioma.

结果:该杂交瘤细胞株分泌抗人脑胶质瘤细胞单克隆抗体H12具有与脑胶质瘤细胞特异性结合的特性。

The age of adakitic dacite is about 514.2±8.5 Ma, and the age of eclogite from the northern margin of Qaidam basin is 494.6±6.5 Ma. Therefore, it is considered that the slab started its subduction in Late Cambrian, that the adakitic magma was formed at the subduction depth of about 75~85 km, and that the partial melting residues with garnet facies continued subducting and finally formed eclogite in Early Ordovician.

据其地球化学研究结果并结合该区埃达克质英安岩(5 14.2± 8.5Ma)和榴辉岩(494.6± 6 。5Ma)的年龄数据,推测柴北缘板片在晚寒武世开始俯冲,俯冲板片在 75~ 85km深处开始部分熔融形成埃达克质岩浆,而熔融残留部分继续俯冲,在早奥陶世形成含石榴石残留相的榴辉岩。

DATA SYNTHESIS: Il-17 exerted the biological function after combines with its receptor maybe induced the occurrence and the development of the osteoarthritis by the way of increasing the chondrocyte, expression of inducible nitricoxide synthase and nitrogen monoxide, boosting up the tbe chondrocyte and the expression of MMP-1/3/13, boosting up the activation of the aggrecanase and the collagenase, boosting the decompose of the cartilage proteoglycan and collagen, boosting up the monocyte evocable breakage of the cartilaginous matrix.

资料综合:白细胞介素17通过与其受体结合发挥生物学作用,其可能通过增加关节软骨细胞诱导性一氧化氮合酶表达和一氧化氮产量,增强软骨细胞基质金属蛋白酶(MMP-1/3/13)的表达,增强蛋白聚糖酶和胶原酶活性,促进软骨蛋白多糖及胶原降解,并增强单核细胞对软骨基质的破坏,从而诱导和加速骨关节炎的发生和发展。

In the final steps of glycogenolysis and gluconeogenesis, intracellular glucose-6-phosphate (G6P) is transported from the cytoplasm to the lumen of the ER by glucose-6-phophate transporter (G6pt) where is hydrolysed to glucose and phosphate by glucose-6-phosphatase (G6Pase).

在肝醣分解与醣质新生作用的最后步骤中,G6pt携带著G6P从细胞质至内质网膜,再与G6Pase结合,进而水解成葡萄糖与磷酸。

Long-term with the Luoyang Refractory Material Research Institute, Beijing University of Science and Technology, Anshan University of Science and Technology, such as metallurgy research institutions to collaborate, has developed the metallurgy, coking industry in various grades×, silica brick, clay brick, magnesia brick, magnesia-chrome brick, MgO-C Bricks aluminum, chromium corundum brick, insulation brick light, etc.; cement industry with anti-spalling×, alkali brick, silicon brick Mo, direct combination of magnesia-chrome brick, periclase-spinel brick, phosphorus acid brick, high-phosphate soft Dutch bricks, special bricks, such as phosphate; generating boiler industry with a variety of brands wear-resistant brick, corundum brick, mullite brick, such as stereotyped products and wear resistant castable, corundum castable, high-strength low cement castable, impermeable material, gravity feed can be plastic, various grades, such as fire-resistant mud Unshaped Materials, in which silica brick and light insulation brick production line for the national output of a single one of the largest production line.

公司长期与洛阳耐火材料研究院,北京科技大学,鞍山冶金科技大学等科研院校开展协作,先后开发出冶金,焦化行业用各种牌号高铝砖,硅砖,粘土砖、镁砖,镁铬砖,铝镁碳砖,铬刚玉砖,轻质隔热砖等;水泥行业用抗剥落高铝砖,耐碱砖、硅莫砖,直接结合镁铬砖、方镁石尖晶石砖、磷酸盐砖,高荷软磷酸盐砖、特种磷酸盐砖等;发电锅炉行业用各种牌号耐磨砖,刚玉砖,莫来石砖等定型产品和耐磨浇注料、刚玉浇注料、低水泥高强浇注料、防渗料,自流料,可塑料、各种牌号耐火泥等不定型材料,其中硅砖和轻质隔热砖生产线为全国单台产量最大的生产线之一。

PH-20 is a traditional sperm membrane antigen,and it is a glycophosphatidylinositolanchored hyaluronidase.

PH-20(posterior head 20)作为传统的精子膜抗原,是由磷脂酰肌醇(glycophosphatidylinositol,GPI)锚定的膜结合型透明质酸酶,最适PH值呈中性,它分布于精子表面浆膜和顶体内膜,是一种透明质酸酶诱导信号转导的受体和识别透明带的受体。

The penetrability of liposome together with natural silk protein, silicon, vitamin E and Pro-B5 comprises of a high-concentration lipoprotein treatment system, which increase the protein cells and keratose of hair, completely lock the moisture and revive the damaged hair, shine as diamond.

脂质体的渗透力结合真丝蛋白、矽元素、维生素 E 及 Pro-B5,构成一组高浓度脂质蛋白修护系统,增加发细胞的蛋白质形成和角质物质,将水分完全锁住不流失,令受损发丝重获新生,如钻石般闪亮

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