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Matrix attachment region(MARis the DNA sequence that binds to nuclear matrice in eukaryote organisms.

核基质结合区(MAR是真核生物中能与核基质结合的DNA片段。

The Chitinase of Saccharomyces cerevisiae(CTS1-2) is an Endochitinase which is endogenous in Saccharomyces cerevisiae. Its recognition and slipt site lies in the β-1,4 glucosidic linkage of homopolymer. Included in the amino acid sequence from N-terminal to C-terminal of the Saccharomyces cerevisiae chitinase are signal peptide sequence, catalytic domain, binding domain and a C-terminal shorten region.

酿酒酵母几丁质酶(Chitinase,CTS1-2)是一种来自酿酒酵母的内切几丁质酶,它的酶切位点位于其同聚物内的β-1,4连接的糖苷键,酶蛋白分子结构从N端到C端依次为信号肽、几丁质催化区、几丁质结合区以及一个短的C末端区。

GC-MS or LC-MS is a kind of modern,fair chemical analytical technique,which combine higher separation ofChromatography with strong identification of Mass.It was applied in new drug research including concentration determination,impuritycheck,pharmacokinetic,anabolite analysis and so on.The paper reviews their application examples for recent years and shows itsdevelopment future.

气一质联用法和液一质联用法将色谱的高分离性能和质谱的高鉴别特点相结合,组成了较完美的现代分析技术,在新药研究的含量测定,有关物质检查、质量标准制定以及药物动力学研究的代谢物分析、药物及代谢物的体内浓度分布等试验中,成为有力的分析工具,文章综述了近年来色谱一质谱联用在以上领域的应用实例,展示了它的发展前景。

Secondly, referring to the present study on the connotation of the medium-income group and its measurement of dividing, the paper puts forward the basis and method of the sexenary division of the citizens and defines of the medium-income group as a group of people whose income is just lower than the millionaire and billionaire, Similar to the "middle class" popular in the western countries in economy and politics. As tar as the measurement is concerned, the paper sets up the measurement considering both the quality and quantity on the basis of income. From the point of view of quality, the medium-incomes should be able to pay for the real estate, life-lone education, medical care and luxurious goods all or mostly by their personal income, inheritance or loan form banks. In addition, they should be capable of keeping their income rising steadily.

其次,结合当前学术界对中等收入者的内涵及其划分标准的研究现状,本文提出城乡居民六等分的依据和方法,将本文研究视野中的中等收入者概括为一类仅次于亿万富翁和百万富翁的高收入者,在经济特征上,类似于西方世界流行的&中产阶级&;在其划分标准上,确立了以收入作为划分不同群体的依据,衡量标准采用质与量相结合的方法,从质上看,中等收入者的收入应能全部或绝大部分通过借贷、继承等方式支付房产、教育、医疗、高档消费等支出,并具有可持续增长的收入能力。

Based on the regional tectonic evolution, combined with the high precision isotopic ages from this paper and other geologists, we have some new acquaintances as follows: 1 There has no Caledonian granite belt distributed in north margin of North China Craton. So, the traditional evolving model of North China Carton, which formed on this idea and the acquaintance about the collision of North China plate and Siberian plate, must be incorrect; 2 The age date show that the earliest magmatic activity began since late-Palaeozoic Permian, which is inconsistent with the previous idea that there were Caledonian and Hercynian active continental margin in the north of North China Craton and in the south Xingkai Massif. 3 the crust and lithosphere were thickened by the subduction and collision of Siberia plate and North China plate during Late Paleozoic. The magma is formed when the crust is heated and melts caused by thickened lithosphere delamination and caused the Asthenosphere upwelling. But only a little basaltic magma erupted, most magma underplate under the bottom of the crust. Thermal energy derived from basaltic magma underplating made the middle and lower crust melt partially and the late Permian-early Triassic granites is formed in large scale.

根据区域构造演化分析,并结合本文及他人高精度同位素年龄,我们对延边花岗岩形成的大地构造环境有了新的认识:1在华北地台北缘并不存在所谓的加里东花岗岩带,因此,建立在此之上的传统的华北地台北缘演化模式及有关西伯利亚板块与华北板块的碰撞拼合的认识也必然是不正确的;2华北地台北缘和兴凯地块南缘不存在加里东期和海西期花岗岩带,表明两地块边缘最早的花岗质岩浆活动始于晚古生代的二叠纪,即不存在传统观点所认为的加里东期或海西期活动陆缘;3晚古生代由于西伯利亚板块与华北板块的俯冲碰撞,致使地壳和岩石圈增厚,导致加厚岩石圈发生拆沉作用,使得软流圈上涌,加热地壳使之熔融形成岩浆,但玄武质岩浆少量喷出地表,大部分底侵于地壳底部,形成下地壳高密度的玄武质底侵层,玄武质岩浆底侵的热能引起中下地壳广泛部分熔融,形成大面积分布的晚二叠世—早三叠世花岗岩。

Moreover, using the in vilro DNA-matrix binding assay results showed that HS2, HS3 and HS4 core DNA sequences were unable to bind to the nuclear matrix isolated from uninduced HEL cells; in addition, HS2 core DNA sequence was capable of binding to the nuclear matrix prepared from Hu-induced HEL cells, while both HS3 and HS4 can not bind to it.

同时,运用核基质与DNA体外结合实验表明,这些核心DNA序列均不能与非诱导的HEL细胞内的核基质结合。

All these results suppose that COCH gene may play an architectural function in inner ear mesenchymic extracellular matrix, and this architectural stability is critical for the potassium recycling in cochleae and the normal level of endocochlear potential.

COCH基因功能的初步推论,COCH基因可能编码内耳间质组织中一种分泌型糖蛋白,通过与间质组织中其它细胞外基质成分的结合,共同形成稳定的细胞外基质结构框架。

The protein interaction domains was delineated at the N-terminal 50-amino-acid fragment of HCV core protein and the C-terminus of p53. Confocal analysis also revealed that these two proteins colocalize in subnuclear granules and peri-nuclear region. Transfection experiments using a p53-responsive reporter plasmid in HuH-7, Hep3B, HepG2 and H1299 demostrated that full-length HCV core protein could elicit a positive or negative effect on the p53-mediated transcriptional activation depending on the concentration of the HCV core protein.

更且利用p53蛋白C端删除55-95个胺基酸之质体与含p53蛋白结合区之报导基因和表现全长HCV核心蛋白三者之质体於H1299细胞株进行共同转染时,与全长p53蛋白比较,发现HCV核心从增强全长p53蛋白之转活化能力转为抑制p53蛋白缺乏C端55-95个胺基酸之转活化能力,因实验室已有结果证实活体外及活体内缺乏C端55个及75个胺基酸之p53蛋白无法与HCV核心蛋白进行结合(Kao, unpublished data)。

Another role of siRNA is directing RITS complex to bind with homologue chromosome, and then induces heterochromatinization.

除了与RISC结合外,siRNA还引导了RITS复合物结合到同源染色质,介导异染色质化过程。

METHODS: Non-derivatised cuvette immobilised Lipid A was used to track the bonding between the Lipid A and aqueous extracts and alcoholic extracts from seventy-eight TCM, and then neutralized endotoxin in vitro by selecting hypso-bonding TCM that removed the tannins.

将革兰阴性细菌的脂质A包被于生物传感器的非衍生板建立靶点,跟踪测定赤芍、大黄、黄芩等78种中药的水提物和醇提物与Lipid A的结合活性,再将筛选出的中药去鞣质后与定量的内毒素(LPS,20、50ng·ml^-1)37℃孵育30min后,测定孵育后的样品与Lipid A的结合情况,以评价样品内的活性物质含量。

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Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时,他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了

The enrich the peopling of Deng Xiaoping of century great person thought, it is the main component in system of theory of Deng Xiaoping economy, it is a when our country economy builds basic task important facet.

世纪伟人邓小平的富民思想,是邓小平经济理论体系中的重要组成部分,是我国经济建设根本任务的一个重要方面。