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We find the deep Y-shaped hydrophobic pocket spans SPE16 and the hydrophobic patch at the SPE16 surface binded apolar ligands ANS in SPE16 .

SPE16复合物的结构显示存在于SPE16结构中的Y型疏水空穴和分子表面的疏水区有结合非极性分子的功能,显示SPE16蛋白除了RNase酶活性以外的结合功能。

Considering the CHAC's historical reform and the characteristics as a state-owned corporation, and combining the developing trend of china's car trading industry, the paper runs into deep to analyze the outside and inner developing environment of CHAC.

根据华星汽贸的历史沿革和国有大型企业集团的特点,结合中国汽车贸易的发展和前景,本文采用理论联系实际、定量与定性相结合的研究方法对华星汽贸的外部环境和内部环境进行了深入、细致地分析,对公司内部的人、财、物的状况及优劣势进行了研究,确定了公司的远景目标和中长期发展战略;并根据公司整体发展战略制定了各项职能策略。

For example, we have conducted the sequence screening on the binding sites of the interface of Barnase/Barstar complex and found that our DGA method can not only determine which position is more conservative and more important, but also redesign the binding sites rationally. The random sequence design for α,β,α/β and α+β four folding motifs have also been practiced and revealed that there are both homology evolution and heterology evolution of protein sequences compatible the same backbone motif.

例如,通过对典型的Barnase/Barstar复合物界面研究发现,它可以确定界面结合位点的重要性和保守性,并对结合位点进行合理的序列重新设计;通过对α、β、α/β、α+β等四种折叠模式骨架的随机序列设计,发现在蛋白质进化过程中,对同一种结构模式同时存在序列的同源进化和非同源进化这两种趋势。

If an inducer molecule is present, it binds to repressor and changes its conformation so that it is unable to bind to the operator.

若存在着一个诱导物分子,它会与阻遏基因结合,并改变它的构造,使它不能与操纵基因结合。

However certain molecules called corepressors can bind to the repressor protein and change its conformation so that it can bind to the operator.

但是,某些称为共同抑制物的分子可以与阻遏蛋白质结合,并改变它的构造,使得它能与操纵基因结合。

The RRS intensity was enhanced obviously after the drugs and DNA reacting with each other, which indicated the formation of new products for the maximum peak appeared at around 375 nm with slight red shift. Then the Cu ion was added into the system to form a ternary system, and the RRS intensity was enhanced significantly, when the enhanced spectral value was directly proportional to the concentration of the DNA. Thus a highly sensitive method could be obtained for determining DNA and the detection limit of the experiment reached 9.7 ng/mL for the RFSV system.

两者反应形成结合产物后其RRS明显增强,并在375 nm左右出现最大散射峰,且有不同程度的红移和散射增强,说明两者结合成新的产物;加入Cu2+离子后, Cu2+与利福霉素抗生素及DNA形成三元复合物,此时将导致RRS进一步剧增,而且RRS光谱增强值与DNA浓度呈正比,因而可用于DNA测定具有较高的灵敏度,实验对ctDNA的检出限为9.7 ng/mL (RFSV-Cu2+- ctDNA体系)。

First, the significant of co-factor InsP6 and center water in the mechanism of auxins are explored by docking; second, the experiments that compared with the docking rusults of two situations involving fully rigid and selective flexible of active residue of the receptor TIR1 illuminate that selective flexibility docking by AutoDock4 reports more rational results, so that, AutoDock4 dockings are implemented with TIR1-Auxins; third, AutoDock4 docking by TIR1-Auxins-Aux/IAA illuminates that auxin as a molecular glue enhances the interaction between TIR1 receptor and Aux/IAA substrate by the weak interactions, such as hydrogen bond and hydrophobic interaction, furthermore, the weak interactions between receptor protein and ligands greatly influence on auxin activity of auxin ligands.

首先, 通过分子对接计算研究辅酶InsP6以及中心水分子在生长素反应中的重要作用;其次,比较受体大分子完全刚性以及活性残基部分柔性的两种情况下的分子对接结果,说明AutoDock4实现了受体分子活性残基的部分柔性而使对接结果更加合理,进而使用AutoDock4方法对TIR1-Auxins体系进行对接计算;最后,对TIR1-Auxins-Aux/IAA体系进行分子对接计算,结果表明,生长素配体分子作为&分子胶水&直接与受体大分子TIR1以及底物多肽Aux/IAA形成强的弱相互作用,如氢键作用、疏水相互作用,促进了受体TIR1与Aux/IAA底物之间的结合,进而说明氢键作用和疏水相互作用等弱相互作用对于生长素分子的活性具有很大的影响。

As for the long-chained guests such as cationic surfactants with different length of alkyl chain added, they can insert into the CD cavity as a spacer to form a ternary inclusion complex with the host molecule.

同时还发现,化学修饰的环糊精所连发色团与CD形成的&自包结&配合物较相同发光分子与非修饰的环糊精形成的包结物具有更强的结合能力。

Of 12 tomato lines, the analysis on the 4 fruit nourishment quality traits (the contents of vitamin C, total soluble solids and dry matter and ratio of sugar-acid ) was carried out to study the four kinds of disparities, which included the interspecific one, the one between two varieties in the same species , the one between the lines bred by different means in the same variety ,and the one between the different fruit-shaped lines in the same variety .The analytic method of orthogonal comparison of single degree of freedom was applied. The results showed that the line of Lycopersicum pimpinellifolium was better than the average of the lines of L.esculentum in the 4 traits at significant level of 1%, the average of the lines of var.cerasiforme was better than the average of the lines of var.vulgare in the 4 traits at significant level of 5% or 1%,and the two space mutation line(YH02-2 or YH02-6) was better than the average of the other lines of the same variation in the 4 trait, respectively, at significant level of 1%. Of the lines of var.cerasiforme , the lines with pear fruit were lower than the average of the lines with round-shaped or plum-shaped fruits in the 2traits(the contents of vitamin C and total soluble solids), at significant level of 1%,the lines with plum-shaped fruits were higher than the average of the lines with round-shaped fruits, at significant level of 1%,and the lines with yellow-colored fruits(YH02-11) was lower than the average of the lines with red-colored fruits(YH02-1and YH02-7) in the trait of the contents of vitamin C.

对12个品系进行种间、种内变种间、变种内不同选育方式间、变种内不同果实形状间在果实营养品质(果实维生素C含量、可溶性固形物含量、干物质含量和糖酸比)上的差异进行分析,采用统计学上单一自由度正交比较分析法与植物学分类相结合的方法进行分析,结果表明:醋栗番茄种品系YH02-12在4个营养品质性状上,极显著高于普通番茄种品系;樱桃番茄变种品系在4个营养品质性状上的平均水平极显著或显著高于普通番茄变种品系的平均水平;2个空间诱变品系YH02-2、YH02-6在4个营养品质性状上均极显著高于同变种的其他品系的平均水平;樱桃番茄变种品系中,梨形果品系YH02-5、YH02-8的果实维生素C、可溶性固形物含量均极显著地低于樱桃番茄变种中圆形或李形品系的平均水平,李形果品系YH02-9在4个营养品质性状上均极显著地高于圆形果品系的平均水平,黄色圆形果品系YH02-11的果实维生素C偏低于红色圆形果品系YH02-1和YH02-7。

The star SBS was synthesized with cyclohexane as solvent,tetrahydrofuran as activator,n- butyl lithium as initiator and silicon tetrachloride as coupling agent.

星形SBS合成中具有实际价值的工艺是用多官能团的偶联剂使单官能团的活性双嵌段共聚物结合在一起,成为星形嵌段共聚物[1]。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?