结合核

By using multi-dimensional nuclear magnetic resonance method we have studied the folding mechanism of staphylococcal nuclease in vitro; the tertiary interactions for folding of SNase fragments into native-like conformation; the interaction between SNase N- and C-terminal subunits; the relationship of enzyme activity with folding and dynamic states of SNase; the structural properties of enzyme protein while exert its function. We have studied the internal motions of thermophilic Archaea protein Ssh10b and mechanism of its heat-resistance using the NMR 1H-15N relaxation and H/D exchange methods. We have determined the 3D solution structure of human translationally controlled tumor protein TCTP and the Ca2+-binding site; determined the 3D crystal structure of human mitoNEET, a novel protein from distinct groups of iron-sulfur proteins; determined the 3D solution structure of a novel chromatin protein Cren7. Determination of SNase-DNA and Archaea protein-DNA complex structures are in progress.

运用异核多维核磁共振方法研究了金黄色葡萄球菌酶体外折叠机制，酶蛋白片段体外折叠成类天然溶液三维构象的三级相互作用力，酶蛋白亚基间的相互作用，酶蛋白的折叠以及内运动状态与酶活力的关系，酶蛋白发挥功能时的结构特性；运用NMR的1H-15N 驰豫和H/D交换方法研究了嗜热古菌蛋白质Ssh10b双体结构内运动特性，热稳定性机制；确定了人翻译控制的肿瘤蛋白TCTP蛋白的溶液三维结构及其钙离子的结合部位；确定了一类新的铁硫蛋白家族蛋白人线粒体膜上mitoNEET蛋白的晶体结构；确定了一个新型的染色质蛋白Cren7的溶液三维结构；正在研究金黄色葡萄球菌酶及嗜热古菌蛋白质与DNA复合体的溶液三维结构。

SUMO has been shown to covalently modify a large number of proteins, reversible modification by SUMO regulates nucleocytoplasmic translocalization, protein-DNA binding activity, protein-protein interaction, transcriptional regulation, DNA repair, and genome organization.

SUMO与靶蛋白之间这种可逆的共价连接，在核质运输、DNA 与蛋白质结合活性、蛋白质之间相互作用、转录调控、DNA 修复以及维持基因组稳定等方面均发挥着重要的调节作用。

In order to analyze the neutron spectrum effects on radiation damage, a computer code is designed to calculate recoils, fragments , transmutational products and their energy spectrum.

分析了中子与靶原子的相互作用过程，提出了结合中子输运和核反应耦合模型，采用由蒙特卡罗方法编写的RDSNC程序计算了聚变堆第一壁候选材料SiCf，/SiC在14 MeV和1 MeV中子辐照后的反冲核、碎片、嬗变产物和它们的能谱。

Both iron atoms of the binuclear unit are bridged by one oxy atom and two acetate groups. Each iron atom is also bound to facially - coordinating tridentate IDB ligand with the aliphatic nitrogen donor situated trans to theμ- oxy atom. Each iron centers is in a distorted octahedral symmetry.

每个双核单元的两个铁原子均通过一个氧原子和两个醋酸根连接，每个铁原子同时还与位于桥氧原子对位的三齿配体IDB重脂肪链上氮原子相结合，每个铁中心为一变形八面体结构。

Heat shock factor binding protein 1(HSBP1) is a nuclear-localized, novel, conserved, low molecular weight (00 residues) transcriptional factor, which may repress the activity of the heat shock factor 1 (HSF1) by binding HSF1 active trimerization domain.

热激因子结合蛋白1（heat shock factor binding protein 1， HSBP1）是一种新发现的高保守、低分子质量、定位于核中的一种转录因子，它可抑制HSF1的转录域活性，并协同HSP70负调控热激反应。

Observation were made on the fertilization and embryo development in wide hybridization between Triticum aestivum L.

本文还报道了小麦与节节麦远缘杂交时雌雄性核的结合及杂种胚和胚乳的发育情况，探讨了小麦与节节麦杂交结实率低在胚胎学方面的原

Those undecomposed 2:14:1 phase could be the nucleation centre during DR process while the decomposed mixture formed c-axis texture of Nd_2_(14)B.

在脱氢再结合时，歧化产物以未分解的Nd_2_(14)B为形核中心，晶粒择优生长，生成各向异性永磁体。

We set up the angular momentum conservation model of wind accretion of Ba stars, and then derive the change equations of the orbital elements. Finally, combining the heavy element nucleosynthesis of AGB stars, we creatively calculate the heavy-element overabundances of barium stars in a self-consistent manner adopting accreting and mixing on successive occasions.

我们建立了Ba星形成的星风吸积的角动量守恒模型，推导出其轨道根数的变化方程，并结合AGB星的重元素核合成，通过逐次脉冲吸积与混合，自洽地计算出Ba星的重元素超丰。

Researchers at the University of California, Los Angeles, and The Hospital for Sick Children in Toronto monitored neurons in the lateral amygdalae (two almond-shaped regions on either side of the midbrain associated with learning and memory) of mice to see whether the presence of the CREB protein plays a key role in signaling brain cells to make memories.

洛杉矶加利福尼亚大学及多伦多儿童医院的研究者们对小鼠外侧杏仁核部位（该部位是主管学习和记忆的中脑两侧杏仁状的区域）进行监测，以研究CREB蛋白（cAMP反应元件结合蛋白）是否在脑细胞形成记忆过程中起着至关重要的作用。

Using Perl as programming language and integrating databases technology, microsatellites, longer than 12 nucleotides in length, in 29 eukaryotic and 1180 prokaryotic genomes were computed and censused in great scale.

本研究采用Perl为编程语言结合数据库技术等方法，对29个真核生物基因组和1180个原核生物基因组的DNA序列上长度超过12的微卫星进行了大规模的计算和统计分析。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。