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The methods of theory analyses and digital simulation have been used in this thesis and several schemes of strapdown guidance law based on analyzing the performance of several classical guidance laws have also been present according to the characteristics of strapdown Anti-Radiation homing seeker. The stapdown guidance systems were built for a certain Anti-Radiation missile, adopting acceleration autopilot and the attitude autopilot, and the paper has focus on analyzing the performance of low frequency strapdown Anti-Radiation homing seeker. The Approaches of lead correction and dead-zone relay control were given to improve the guidance precision, and also the increasable observability law was attempt and validate.

本文采用理论分析和仿真实验相结合的方法,在对经典制导律进行理论分析和验证的基础上,针对捷联反辐射导引头的特点,提出了捷联制导律多种设计方案,并以某型反辐射导弹为应用背景,分别采用姿态角反馈自动驾驶仪和过载反馈自动驾驶仪构造了捷联制导系统,重点基于反辐射导引头的低频端特性,开展了捷联制导律的导引性能对比分析工作,提出了应用超前校正和带死区继电控制提高制导精度的方法,并对提高可观测性的捷联制导算法的实现思路进行了尝试和验证。

He penetratingly developed Lenin's idea about the crux and corc of materialist dialectics, deeply elaborated Lenin's theory on two kinds of development. He solved a series of practical problems by integrating this theory with the practice of the Chinese revolution.

精辟地发挥了列宁关于唯物辩证法的实质和核心问题的思想;深刻地发挥了列宁关于两种发展观的理论,把这个理论同中国革命实践相结合,解决了一系列的实际问题;阐述了矛盾的普遍性与特殊性,把对立统一规律作了具体而全面的展开,阐述了矛盾同一性的相对性和斗争性的绝对性,以及它们之间的相互关系。

A detail comparison demonstrates that such preconditioned IbpB is distinguished from the non-preconditioned IbpB by a remarkable conformational transformation, including a significant increase in the flexibility of the N- and C-terminal regions, as well as enhanced dynamic subunit dissociation/reassociation.

我们的比较研究表明,这样的经过热休克预处理过的 IbpB蛋白与未经历过热休克条件的蛋白之间存在很大的构象上的差异,包括前者在N-和C-末端区域可曲性的明显增强,以及亚基动态分离/重结合的加强。

In this study, nonionic surfactant sorbitan trioleate (Span 85) was modified with Cibacron Blue F-3GA to become an affinity surfactant (CB-Span 85) and to form affinity-based reversed micelles while dissolved in hexane. Since the CB molecule possesses a specific conformation that mimics nicotinamide adenine dinucleotide, it can bind strongly and specifically to a wide range of nucleotide-dependent enzymes such as dehydrogenases and kinases. Moreover, high protein transfer efficiency in the reverse micelles can be easily achieved by controlling the ionic strength of the aqueous phase.

本实验使用非离子型界面活性剂Span 85与蓝色染料分子Cibacron Blue F-3GA结合,形成具有亲和性的界面活性剂 CB-Span 85,由於CB染料分子具有与NAD+相似的结构,可与含核苷酸部位的蛋白质具有亲和力,将CB-Span 85溶於有机溶剂形成反微胞相,可有效的提高反微胞的选择率,可以只控制离子强度来调节蛋白质进出反微胞的效率。

The third part touches upon the enlightenments gained from the study on the relationship between paradox and mathematical logic on the relationship between paradox and mathematical logic, which are the following: so long as we combine the way of formalization with the philosophizing analysis, look at things dialectically, and deal with things systematically, not only can the problem of paradox be solved relatively, but also a series of important discovery can be found in the process of resolution to it.

第三部分论述在探析悖论与数理逻辑的关系中所得到的意义和启示:只要我们把形式化的方法和哲学性的分析结合起来,用辩证的观点看问题,用系统的方法研究问题,悖论不但可以得到相对的解决,而且在解决悖论的过程中会引出一系列的重大发现。

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f_2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuilles law of laminar flow.

因此,本文以难溶性的格列齐特为模型药物,在传统型推拉式渗透泵的基础上,设计并制备了双面打孔型推拉式渗透泵;通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面,对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察,同时,应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究;在此基础上,通过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定,结合流体力学中的Poiseuille层流定律方程,对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此,本文以难溶性的格列齐特为模型药物,在传统型推拉式渗透泵的基础上,设计并制备了双面打孔型推拉式渗透泵;通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面,对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察,同时,应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究;在此基础上,通·药学论文过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定,结合流体力学中的Poiseuille层流定律方程,对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此,本文以难溶性的格列齐特为模型药物,在传统型推拉式渗透泵的基础上,设计并制备了双面打孔型推拉式渗透泵;通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面,对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察,同时,应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究;在此基础上,通过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定,结合流体力学中的Poiseuille层流定律方程,对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

This anion pump is composed of two subunits, the catalytic 63KDa ArsA, a hydrophilic protein, when purified, exhibits oxyanion-stimulated ATPase activity, the hydrophobic 45. 5KDa ArsB protein, located in the inner membrane of E. coli, is the putative anion translocating channel and also serves as the anchor for ArsA to attach on the membrane.

ArsATP酶由水溶性的63KDa的ArsA蛋白和膜整合的46KDa的ArsB蛋白组成,ArsA蛋白是催化亚基,具有亚砷酸盐和亚锑酸盐激活的ATP酶活性,ArsB蛋白则构成转运亚砷酸盐和亚锑酸盐的阴离子通道,同时作为ArsA蛋白在膜上的结合位点。

How to exactly measure the coal mass of pulverizer in fossil power plant is one of primary causes that the efficiency of milling control is low and the automation is difficult to running. Aiming at the limitation of evidential theory, As the neural network has self-organize, self-learn, collateral distributing manage, strong fault tolerant and robustness, we combined the evidential theory and the neural network and put forward a two-step fusion method.

火电厂中钢球磨煤机筒内存煤量的测量问题一直是制粉控制效率低和自动控制难以投入运行的主要原因之一,针对D-S 证据理论存在的不足,而利用神经网络具有的自组织、自学习、并行分布处理、高度容错性和鲁棒性的特点,本文提出了一种将证据理论与神经网络相结合的数据融合方法,并将其用于解决球磨机存煤量的测量问题。

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