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The purpose of this research is to discuss the probable mechanism of acupuncture treatment combined with pharmacotherapy regulating glutamatergic function and anti-free radical effect on the dementia rats due to hippocampal CA, lesions induced by quinolinic acid. So that the author can provide the clinical application of acupuncture treatment combined with pharmacotherapy with experimental evidences in treating Alzheimers disease.

本文的研究目的是探讨针药结合对喹啉酸(Quinolinic Acid,QA)损毁海马CA_1区所致痴呆大鼠模型的中枢兴奋性神经递质谷氨酸(glutamate,Glu)和抗氧化指标的影响及其对提高痴呆大鼠学习记忆能力的可能机理,为临床针药结合治疗阿尔茨海默氏病(Alzheimers disease,AD)提供实验依据。

The SPECT imaging of ~(99)Tc~m-GEBP11 can show the tumor mass clearly and ~(131)I-GEBP11 has anti-tumor effect with weak toxicant and secondary effect, which is the foundation for them to develop nuclide probe or radiotherapeutics drugs targeting to tumor vasculature.3. GEBP11 can inhibit angiogenesis, which comes true probably through its inhibition effects on the proliferation, invasion, migration and adherence of ECs.

1、GEBP11具有活体内胃癌血管靶向结合的能力,它与胃癌血管内皮细胞膜受体特异结合后可被内化。2、~(99)Tc~m-GEBP11 SPECT成像能较好地显示体内肿瘤灶,~(131)I-GEBP11具有明显的抗肿瘤效应及较弱的毒副作用,为开发肿瘤血管成像核素探针及受体放射治疗新药奠定了基础。3、GEBP11具有抑制胃癌血管生成的作用,这可能通过抑制ECs增殖、基质降解及迁移、粘附能力实现。

Methods: MUC1/Y extracellular domain was used as a target molecule to biopan Ph. D. 12 phage randem peptide library. Two protocols using affinity gel and cell culture plates respectively were carried out. Positive phage clones were identified by ELISA. ssDNA sequencing was done on 16 positive phage clones to get the amino acid sequences of MUC1/Y-binding peptides. Immunohistochemistry was done to show the capacity and specificity of positive phage clones to bind the tumor cell lines.

以MUC1/Y黏蛋白的胞外段蛋白(MUC1/Yex)为靶分子,用凝胶亲和法和酶联板法分别筛选十二肽噬菌体随机肽库,ELISA鉴定阳性克隆,DNA序列测定后确定MUC1/Yex结合肽的氨基酸序列;免疫组化鉴定阳性噬菌体克隆与正常及肿瘤细胞的结合能力及特异性。

The product has e-learning function: it combined reelable "Paper Screen" with "Yoga Mat". It is shaped in tubular with component stereo system at two sides.

本设计结合线上学习功能,将可弯曲的PAPER SCREEN和瑜珈垫结合,作整体产品收纳的设计。

Selects in the material on inorder to for person by mystical graceful graceful feminine daydream,both must leave the dust refinedly, and does not lose the nationalclothing characteristic, therefore must select with it feeling closelining, the pure silk, the tissue, the flower bud silk unionutilization, suddenly reveals its mystically, is graceful; Is and theblack gray and so on other colors embellishes using the clothing wholepurple, achieved the harmonious feeling, echoes with the subject;Again take has the national style design, lace element and so onsplicing as the design spot, joins the modern clothing synthesis tocut out the idea, during attenion popular element, needs to derivethis nationality traditional culture and the national specialcharacteristic penetrates from the national clothing color and themodelling into during the fashion female attire design, manifestsAmerica of the fashion which the national culture and the modern tidalcurrent unifies.

在材料的选用上为了给人以神秘曼妙优雅的女性遐想,既要出尘脱俗,又不失民族服装特色,因此要选用与之感觉相接近的面料,真丝、薄纱、蕾丝的结合运用,来突显其神秘、优雅;运用服装整体的紫色系与黑色灰色等其他色点缀,来达到和谐的感觉,与主题相呼应;再以有民族风格的图案、花边的拼接等元素为设计点,加入现代服装合体的裁剪理念,在注重流行元素的同时,更需要汲取本民族传统文化和民族特质从民族服装色彩及造型深入到时尚女装的设计之中,体现民族文化与现代潮流相结合的时尚之美。

From radiative protection side, my methods of malignant disease diagnosis and dangerous degree analysis are gave out through standards, regulations and laws which are carried out in the world and successful experiences from radiative material management in foreign countries and current situation of material application and management, which will help us have a scientific radiative material management evaluation system. Through cased study and comparison analysis, in organization reformation, I point out:1. Separate 'supervising right' with 'checking right', it will keep lawexecuting open and fair.2. Main body function reforger after reformation, all levels sanitarian organizations are judges, give judge a new right, all radiative application units are athletes, all activity should be under regulations.

结合国内国际正在实行的标准、法律法规和相关的规章制度,借鉴国外在辐射管理方面的成功经验,结合我省放射性物质应用和监督管理的实际情况,在辐射防护评价方面,我提出恶性疾病个体鉴定的方法和危险度分析方法,使得我们的辐射监督管理有了一套科学的评价系统;采用案例研究和比较分析的方法,从机构改革方面我提出:(1)需要将&监督权&和&检测权&分离,这样才能保证执法管理机构公开公正;(2)改革后的各个主体需要进行职能再造,即各级卫生监督管理机构是裁判员,重新赋予其裁判员的相关职权;各个放射性物质应用单位是运动员,在游戏规则内从事活动;各个放射卫生检测机构作为中介机构,接受管理机构的委托为&运动员&提供有偿服务。

The practice of Bao-steel Group 1780mm steel rolling house shows seamless construction super long and super wide mass concrete box foundation with general concrete, which has no. deformation seam, no repour strip and no special material, can reach good result in cracking control by the sequential construction method, optimization design, material control, concrete curing without increasing the cost or extension.

结合宝钢集团不锈钢1780mm热轧工程超长、超宽的大体积混凝土箱型基础,在施工过程中不设变形缝、不留后浇带、混凝土内不掺特殊材料,采用分块跳仓浇筑施工工艺,结合配合比设计及优化、原材料控制、加强温控和养护等综合技术措施,可在不增加投资、不延长工期的条件下达到有效控制混凝土裂缝的目的。

Amino acid mutant site A43V locates in N-terminal headpiece of represser protein which binds specifically to DNAand amino acids mutant sites S93L, S102N, G315S, Q180R, M2491, I283T all locate in the core region of represser protein which binds to IPTG.

氨基酸突变位点A43V位于阻遏蛋白氨基末端,是阻遏蛋白和操纵基因的结合区;S93L、S102N、G315S、Q180R、M249I、I283T均位于阻遏蛋白核心区,即阻遏蛋白和IPTG结合区。

In order to improve the quality and efficiency of this job, higher vocational colleges actualized Cooperative Education of Enterprise, University and Research rifely. It is a kind of open-style talent training pattern in academia and industry of higher vocational education which combines higher vocational colleges, society and economy, training talents with higher applied technology; is a kind of representation of the university-business partnership in educational field.

为提高高职院校人才培养质量和效率,我国高等职业院校普遍实施了产学研合作教育,它是高等院校与社会经济相结合,在学术环境与产业环境中通过教学、科研和生产实践三方面的结合,培养高技能应用型人才的一种开放式的人才培养模式,是产学研合作在教育教学领域中的一种表现形式。

In the first experiment, CL cells were incubated with 〓-tyrosine at 24℃ for 45 min. The binding of 〓-ty- rosine to the CL cells reached saturation at 12 μM of 〓-tyrosine con- centration.

将黄体细胞与〓-酪氨酸一起孵育(24℃,45min)后,〓-酪氨酸能与黄体细胞特异结合,〓-酪氨酸浓度为12.5μM时达到饱和,在4℃孵育10min的条件下仍有〓-酪氨酸的结合

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。