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Results: Mel specific binding sites were det ermined in 16 kinds of human embryonic tissue and this binding could be inhibit ed by GTPγS, supporting the theory that MR is coupled to inhibitory G-proteins system.

结果:经饱和分析、动力学分析及特异性分析证明人胚胎心、肝、肾及甲状腺等16种组织均存在Mel特异结合位点,亚细胞分布研究表明这些组织中以细胞核及线粒体MR含量最高;GTPγS能够抑制Mel与其受体的结合,使MR的结合容量或亲和力降低。

As well using flameless atomic absorption spectophotometer toanalyse the amount of platinum binding to DNA,we can fand that after 1hour at 37℃ the amount of platinum binding to DNA for BGC-823 acted byCDDP 20ug/ml in hypotonic solution was 30.1±6.2ng/mg·DNA,whilethe isotonic groups were 6.4±1.5ng/mg·DNA.

采用非火焰原子吸收光谱法检测DNA结合铂含量发现,BGC-823经20μg/ml CDDP,37℃作用1小时,低渗给药组DNA结合铂含量为30.1±6.2ng/mg·DNA,等渗给药组DNA结合铂含量为6.4±1.5ng/mg·DNA,两者差异显著(P<0.05),该结果表明低渗溶液能显著增强CDDP与其作用靶点—DNA的交联。

The binding capacities of the water-soluble chitosan and its derivatives to taurocholate and glycocholate as bile salts were investigated in vitro.

修饰后的壳聚糖结合胆酸盐的能力增强,说明引入更多的胺基或铵基有利于对胆酸盐的结合,胺基上烷基与胆酸盐的甾环之间也应当产生疏水相互作用;同样我们在体外也研究了水溶性壳聚糖及其衍生物对硬脂酸钠和十二烷基硫酸钠的结合能力及其影响因素。

The effects of active molecule and repressive molecule on the binding process of allosteric enzyme and substrate are discussed by considering the heterotropic effect of the regulating molecule that binds to allosteric enzyme.

文摘:考虑调节剂结合别构酶的异位效应,讨论了与别构部位结合的活性剂分子和抑制剂分子对别构酶和底物结合过程的影响以及它们对协同性效应和抗协同性效应的影响。

Conbining previous results with our results, we conclude that the soluble gp130 mutant containing CBD can antagonize the biological activities of IL-6 by competitively binding IL-6/IL-6Rα with wild-type gp130, and the membraneanchored mutant could transduce IL-6 signal, but its efficiancy was much lower than that of wild-type gp130, therefore, we thought the Ig-like module also played an important role in IL-6 signal transduction by involving in the formation of a hexameric IL-6 receptor complex.

结合以前的研究结果,我们认为只含胞外CBD区的gp130突变体通过与膜结合型gp130竟争结合IL-6/IL-6Rα复合物而具有拮抗IL-6功能的作用;而只含胞外CBD区的gp130突变体,尽管仍能传导IL-6信号,但其效率远低于野生型gp130,因此,我们认为gp130的Ig样区在IL-6转导中也起着十分重要的作用。

Facing this situation, according to the hortation and assit system for planned parenthood being taking into effect in the rural area of our country, this thesis analyzes the deficiency of the present rural social pension system and discusses countermeasures and approaches about how to combine these two systems and improve the rural social pension system based on the analysis of necessity and feasibility of transition from"selective"hortation and assit system to"prevalent"rural social pension system. This thesis can be separated into five parts.

针对这种现状,本文从分析我国农村社会养老保险制度存在的问题与不足入手,结合当前我国在农村推行的农村部分计划生育家庭奖励扶助养老制度,从理论和现实的角度分析将奖励扶助养老制度与农村社会养老保险制度相结合建立农村计划生育家庭养老保险制度,以及将这种&选择性&的社会养老保险制度向&普惠性&的农村社会养老保险制度过渡的必要性和可行性,在此基础上进一步探讨了如何将两种制度有效结合,以及改进和完善我国农村社会养老保险制度的对策和途径。

The G α subunit will eventually hydrolize the attached GTP to GDP by its inherent enzymatic activity, allowing it to reassociate with G βγ and starting a new cycle.

G蛋白的作用是分子开关,α亚基结合GDP失活,结合GTP活化。α亚基具有GTP酶活性,可催化结合的 GTP水解,恢复到无活性状态。

The combined water of HCP is equal to the one of hydrosilicate and hydroaluminate plus the one of Ca 〓 crystalline which is produced when hydration (named CH-water).

水泥石结合水总量等于水化硅酸盐与水化铝酸盐结合的水量加上水化生成的Ca〓晶体的结合水量。

First described the current production flow about company A briefly; Secondly, analyses its manufacture scene strictly according to theory of constraint thinking process,through structured Current Reality Tree finding out its bottleneck;By structured conflict picture, seek the inflex

首先对A公司生产现场管理现状进行了简要描述;其次结合约束理论,严格按照其思维流程对该公司的生产现场进行了分析,构建了该企业的当前现实树,并找出其瓶颈所在;通过构建冲突图,寻找解决冲突的注入,建立了公司改善的未来现实树;以未来现实树为引导,结合丰田生产方式的一系列现场改善工具,从改善员工工作环境,提高员工满意度,增加员工技能培训,建立一系列制度措施保证现场的秩序化等方面入手,构建了公司的转变树,并得到了良好的执行;最后根据案例的实际运行情况,结合笔者的自身体会,对企业应用约束理论和丰田生产方式改善生产现场的操作流程提出了自己的设想。

Methods Activate groups A and C meningococcal polysaccharide with cyanogens bromide and prepare into MenAPS-ADH and MenCPS-ADH derivatives by reacting with 1, 6-adipic acid dihydrazine. Mix MenAPS-ADH and MenCPS-ADH derivatives with purified tetanus toxoid at a certain mass ratio, then add l-ethyl-3(3-dimethylaminopropyl)-carbodiimide to prepare bulks of MenAPS-TT and MenCPS-TT conjugates respectively. Mix the two bulks at a certain ratio, add stabilizer and lyophilize to prepare group A+C meningococcal polysaccharide conjugate vaccine.

A群和C群脑膜炎球菌多糖在溴化氰的活化下,以1,6己二酰肼作为连接子,与精制破伤风类毒素在碳二亚胺作用下结合,再按一定的比例将两者混合,制成A+C群脑膜炎球菌多糖结合疫苗原液,加保护剂冻干后,制成A+C群脑膜炎球菌多糖结合疫苗。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。