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绒毛

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Human leukocyte antigen-G is a neoclassical human leukocyte class Ⅰ b antigen which was observed to be restrictively expressed by the fetal-maternal inter-fate on the extravillous cytotrophoblast.

人类白细胞抗原-G(human leukocyte antigen-G, HLA-G)属于非经典的HLA-Ⅰ类抗原分子,早期的研究发现HLA-G的表达仅局限于母胎界面的绒毛外细胞滋养层。

From the early study of the pathogenesis of pre-eclampsia people have found its association with immunological function . In 1986 Ellis et al[1] had found that the extravillous chorionic cytotrophoblast contacting with the maternal tissue expressed high levels of Human leukocyte antigen-G, a major histocompatibility tissue-specific antigen . Extravillous chorionic cytotrophoblast with high levels expression of HLA-G proteins can invade the maternal deciduas and the maternal spiral arteries by displacing the endothelial lining and destroying most of the musculoelastic tissue of these arteries .

早期研究开始,许多学者即发现其与免疫学有密切关系,至1986年Ellis等[1]发现人类白细胞抗原(human leukocyte antigen,HLA) G分子高度表达在绒毛外滋养层细胞( extravillous cytotrophoblast,EVCT)上,即浸润至子宫蜕膜层甚至达子宫浅肌层以及子宫螺旋动脉内皮层,与母血及子宫组织直接接触的滋养细胞,这种独特的组织分布提示HLA-G分子在母胎免疫耐受方面起重要作用。

Sometimes no normal decidual plate forms in pregnancy, and placental villi invade directly into myometrium , as seen here.

有时,怀孕后没有正常蜕膜形成,胎盘绒毛直接侵入子宫肌层,这里看见的便是。

Leaves 3 or 4(–8) per ultimate branch; sheath densely deciduously setose; auricles readily deciduous, falcate; oral setae radiate, purple, ca. 3 mm; ligule prominent, ca. 5 mm; blade lanceolate, 10–23 ×(1–)2.5–3.3 cm, secondary veins 7- or 8-paired, abaxially yellow-green and white tomentellate, adaxially light green and glabrous, base asymmetrically cuneate, margins serrulate.

每末级的分枝的叶3或4(-8);鞘浓密具刚毛的脱落的;叶耳容易落叶,镰刀形;口头的刚毛辐射状,变紫,约3毫米;杰出的叶舌,约5毫米;叶片披针形, 10-23 *(1-)2.5-3.3 厘米,次脉7-或8配对,背面的黄绿色和白色短绒毛,正面和无毛的淡绿,不对称的楔形的基部,边缘有细锯齿。

Leaf blade abaxially densely yellow-brown or gray-white tomentose; gland of calyx oblong-lanceolate, base decurrent to pedicel.

叶片背面浓密黄褐色或灰白色被绒毛;长圆状披针形的花萼,基部下延在花梗的腺体。

In GTD, there were no significant relationship between the normal expression of Ecad and the strong expression of LN.

随着GTD恶性程度的增加,Ecad的正常表达率及LN的强表达率逐渐降低,且与正常绒毛组织有显著差异。

In GTD, there were no significant relationship between the normal expression of Ecad and the strong expression of LN.

在葡萄胎、侵蚀性葡萄胎及绒毛膜癌中Ecad的正常表达率分别为53.3%、31.25%和16.67%;LN的强表达率分别为80%、56.25%和50%。

The expression of the Ecad and LN are associated with the development, malignance and invasiveness of GTD.

随着GTD恶性程度的增加,Ecad的正常表达率及LN的强表达率逐渐降低,且与正常绒毛组织有显著差异。

In HM, IM and CC, the normal expression rates of Ecad were 53.3%, 31.25% and 16.67%, respectively; the strong expression rates of LN were 80%, 56.25% and 50%, respectively.

在葡萄胎、侵蚀性葡萄胎及绒毛膜癌中Ecad的正常表达率分别为53.3%、31.25%和16.67%;LN的强表达率分别为80%、56.25%和50%。

With the development of GTD malignancy, the normal expression rates of Ecad and the strong expression rates of LN declined gradually and were significantly different from those of normal villus.

结果 在GTD中,Ecad的正常表达率和LN强表达率分别为37.8%(28/74)和64.86%(48/74),显著低于正常绒毛组织。

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