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Because corticosteroid can modify the immunological process which is considered the major mechanism involved in AHS, it is used to treat AHS clinically. However, corticosteroid therapy may have deleterious effect (e.g., delayed healing of cutaneous lesions, infections, prolonged hospital stay). Therefore, the use of corticosteroids for AHS remains controversial. We reported a 54-year-old man who had underlying diabetes mellitus with chronic renal insufficiency, hypertension and hyperlipidemia. Allopurinol 100mg twice a day was initiated one month prior to admission. After taking the drug for 24 days, he developed a generalized mild itchy eruption on the trunk and upper extremities followed by chillness, fever, ocular discomfort and painful oral ulcer over one-week period and was admitted to the hospital. A skin biopsy revealed changes consistent with Stevens-Johnson syndrome.

本文报告一位54岁的男性患者,有高血压、高血脂、糖尿病及慢性肾脏功能不全的病史,最近发现有高尿酸血症(11.1mg/dL)而开始服用Allopurinol,在服用24日后,因为逐渐发生皮肤红疹搔痒、口腔溃疡、发烧、畏寒以及眼睛不适,一周之后到医院就医,经诊断为服用Allopurinol所造成之史帝文森-强生症候群(Stevens-Johnson syndrome),因而在皮肤科住院接受治疗,由於病人有高血压、高血脂及糖尿病,所以入院后仅以支持疗法,并未给予全身性类固醇,然而病人之病况恶化,并有肾功能恶化,因而於住院两日后,转进肾脏科病房,在使用全身性类固醇治疗之后,病况持续改善,并在2周后出院。

Objective: To study the skin metabolism of leflunomide in neonatal SD rat skin homogenate.

目的:研究来氟米特在新生SD大鼠皮肤匀浆中的代谢作用,为来氟米特经皮给药制剂的研究提供实验依据。

Cell culture cytotoxic test, skin allergy test, intracutaneous stimulation test, primary skin stimulation test, hemolysis test , general acute toxicity test and pyrogenicity test were performed according to the manual of the national standards of medical materials.

方法带瓣牛颈静脉经单宁酸处理后按国家医用材料的要求进行浸提液的制备、细胞毒性试验、过敏试验、皮内刺激试验、原发性皮肤刺激试验、溶血试验、急性全身毒性试验及热原试验等生物学评价试验。

Methods Report 3 cases proven by biopsy of the sural nerve and skin,and analyzed with review of literatures that clinical features,pathological changes and treatment of this diseases.

报告3例经腓肠神经和皮肤活检证实的病例,结合文献分析其临床特点、病理改变及治疗。

The zoopery showed that percutaneous toxicity was low; score of skin irritation intensity was less than 5, without allergenicity; the effective rate on ulcer was 100% in clinical observation, healing rate in 4 weeks was 97.0%.

动物实验:其经皮毒性属低毒;皮肤刺激强度评分<5分值;无致敏性;临床观察对溃疡创面治疗的有效率100%,4周愈合率为97.0%。

Results The flaps survived totally in 26 cases,the distal necrosed partially in 2 cases.18 cases were followed-up for 3 to 24 months,the circulation,color and texture of the flaps were excellent and 2-PD was 11~15 mm.

术后 18 例经 3 个月至 2 年随访,皮瓣外观、血运、质地弹性佳,踝关节功能恢复良好,皮肤感觉有一定的恢复,两点辨别觉为 11~ 15 mm。

We see she has well oriented consciousness, thin body, well appetite, hard stool, thin and red tongue, white and juicy moss on the tongue, sliding and quick pulse, fallen hairs, sometimes cough, skin peeling, even ulcerating over the fingers, big toes and foot plates, suspectedly resulted by inflammation of skin and kid scratch, severelier at midnight.

经介绍至本院看诊,吾见精神安定,体格偏瘦,食欲尚可,大便偏硬,舌体瘦红而苔白润,脉象滑数,掉发现象,时有咳嗽,手指、大足趾与足底处有多处且大面积的脱皮、甚至溃烂,疑皮肤发炎与小儿痒抓所致,夜晚更是严重。

The collagen treated by Protease N can get good biocompatibilily and is suitable for building the trestles of tissue engineering for skin with good bioactivity.

酸溶性胶原经蛋白酶 N处理后,生物相容性良好,适合于皮肤组织工程支架的构建,并具有良好生物活性。

Skin resistance is one of the important parameter of the function of autonomic nervesystem.

皮肤电阻是反映植物神经,特别是交感神经系统机能状态的重要指标之一,常被有关学者应用于人体经穴研究和疾病诊断中。

Human socks webbing built into the electrical conductivity, and then by the conductive rubber ring and the earth pin access land, to ensure that the grounding pin in contact with Central and at the same time, conductive webbing really need to contact with the skin.

产品说明Product description;人体袜子内置入导电织带,再经导电橡胶脚环与大地接入大地,在确保接地脚环与地接触的同时,导电织带需确实与皮肤接触。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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