经皮的

Results Acute oral LD50 were 278 mg/kg and 56.2 mg/kg in rats and mice respectively, while dermal LD50＞2 000 mg/kg and inhalative LC50＞3 000 mg/m3. Skin and eye irritancy were estimated to be negative and mild respectively. Cumulative coefficient was 2.3 and allergic rate was 0%. A negative result was observed in Ames assay while increased frequencies of bone marrow micronuclei and spermatocyte chromosome aberrations were noted in the high dose (11.24 mg/kg) group.

结果 大小鼠急性LD50分别为278 mg/kg和56.2 mg/kg；大鼠经皮LD50＞2 000 mg/kg；急性吸入LC50＞3 000 mg/m3；无皮肤刺激性，轻度眼刺激性；蓄积系数2.3；致敏率为0；Ames试验结果阴性；微核和染色体在高剂量组(11.24 mg/kg)与阴性对照组相比有高度显著性差异(P＜0.01)；大鼠90天亚慢性经口的最大无作用剂量为2.825 mg/kg。

Aim To observe penetrability of paeonol from the gel in vitro.

目的研究丹皮酚凝胶剂中丹皮酚的经皮渗透性。

The key step involves reduction-amination of benzamine and -acetonide glycealdehyde 20 synthesized from cheap and available ascorbic acid . The hydrolysis product of 21 condensed with triphosgene to get 6, key intermediates of Linezolid and Eperizolid. After a series of reactions, we got Linezolid and Eperizolid in reasonable yields and purity. The spectrum and 〓 values of compounds 6 and other intermediates were identical with literature reported.

我们以国内非常便宜易得的维生素C为原料合成得到-丙酮保护的甘油醛20，20和取代苯胺经还原胺化反应制备得到二噁烷21，21水解后与三光气缩合成环得到利奈唑酮和埃皮唑酮的关键中间体6.6经一系列的反应合成得到了利奈唑酮和埃皮唑酮。6及一些中间体的〓D值与文献报道的数据相吻合。

Because of the undeniable fact that even the best of these devices are expected to significantly underperform surgically implanted aortic valves, the justification for their use has been designated as compassionate if the patient is regarded by cardiological and surgical expertise as the most significant or as having an unacceptably high risk for open heart surgery.

一个不争的事实是：即便是最好的经皮植入瓣膜也不如外科手术置换瓣膜效果好。经皮植入人工瓣膜的使用只适用于那些心内科和心外科专家认为开胸手术会有很大风险的患者。

Epidermal cells near the wound dedifferentiate and proliferate forming blastema and/or migrate to the wound plane forming a pre-epidermis consisting of several layers of stem cells covering the wound plane, which then re-differentiates further forming fully developed epidermis. Cells in the parietal peritoneum are also induced by injury to dedifferentiate into stem cells which then proliferate and migrate along the parietal peritoneum to the wound place forming a pre-peritoneum which re-differentiates into fully developed parietal peritoneum.

伤口愈合包括伤口闭合、顶端表皮层及体腔上皮的新生：创伤后的前4 d，残腕顶端的肌肉组织向伤口处迁移并重排使伤口闭合；创伤附近的表皮层细胞发生脱分化并增殖后迁移到创伤面形成由数层干细胞组成的前表皮层，之后进一步分化形成表皮层；而体腔上皮细胞在创伤诱导下也脱分化并增殖，然后沿体腔上皮迁移到创伤处形成&前体腔上皮&，经再分化形成新的体腔上皮。

Methods: From February 2002 to June 2006, 27 patients with upper urinary obstruction due to retroperitoneal fibrosis post-treatment of tumor, under went procedures including retrograde ureteral catheterization, intraluminal ureterotomy and/or balloon dilation, and percutaneous nephrostomy. The efficacy and major complications were summarized.

收集本院2002年l月至2006年6月的27例恶性肿瘤经治疗后发现腹膜后纤维化导致上尿路梗阻的患者，分别接受了经尿道逆行输尿管插管、输尿管狭窄内切开和／或扩张及经皮肾造瘘治疗，总结其疗效和主要并发症。

Results Out of the4527paˉtients treated by ESWL,stones were excreted completely from4512patients within2weeks;12patients who had comˉplication of the urethra stone street were cured by transcutaneous nephrocentesis,nephrostomy and ureterolithotomy through uretercystoscope;stones weretaken out by operation from the other3patients,from whom the excretion of stones was not possible.

目的 探讨ESWL治疗泌尿系结石的效果。方法回顾性分析经ESWL治疗的4527例泌尿系结石病人。结果经ESWL治疗的4527例泌尿系结石病人中，4512例在2周内排尽结石，12例并发输尿管&石街&，加用经皮肾穿刺造瘘和输尿管镜取石治疗，3例中转手术治疗。

Dept. of orthopedics of the People's Hospital of FengRun district TangShan HeBei , 064000,China Percutaneous vertebroplasty is a minimally invasive techniques in spine surgery , solidifiable material is injected into the diseased Vertebro of neck, thoraco and lumbar spine under imaging guidance for the treatment of pain and dysfunction caused by bone cancer and vertebral fractures. the purpose is to let the patients can move early and improve their quality of life.

经皮椎体成形术 Percutaneous Vertebroplasty是脊柱外科领域的一项微创技术，旨在影象引导下经皮向颈、胸、腰椎椎体的病变部位注入凝固性材料用以治疗椎体骨折和溶骨性骨肿瘤引起的疼痛和功能障碍，达到早期下床活动，改善生活质量的目的。

Objective: To Study on transdermal delivery system in vitro of peaonol cataplasms.

目的研究丹皮酚巴布膏剂中丹皮酚的体外经皮吸收情况。

Objective:The purpose of the experiment was to study the carcinogenic and mutagenic effects of petroleum asphalt.

目的：研究石油沥青有无致突变和致癌作用。方法：选用大鼠经口急性毒性试验、Ames试验、小鼠经口微核试验、大鼠气管注入及兔经皮涂抹致癌试验，研究石油氧化及直馏沥青的急性毒性以及致癌和致突变作用。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。