经

A device and method for preparing compound nano fiber endless tow, which contains feeding material liquid to pair of electric spinning nozzle on frame, each nozzle respectively applied with high dc voltage with opposite polarity, each pair of nozzle jetting out nano fiber with opposite electric charge, said nano fiber attracting and colliding each other to form compound nano fiber, then forming nano fiber endless tow after drawing and stretching, the first opposite set pair of electric spinning nozzle jetted compound nano fiber endless tow is stretched down and used as acceptor which covered by the nano fiber jetted by second pair of nozzle an d forming two layers of compound nano fiber endless tow after drawing and stretching, in turn to get multilayer compound nano fiber endless tow after drawing and stretching by godet roller.

复合纳米纤维长丝束制备装置及其制备方法是一种简单、高效电纺制备纳米纤维长丝束的方法，其步骤为将料液输送给支架(3)上的电纺喷头对(1)；喷口相向的电纺喷头对(1)的每个喷头分别施加相反极性的直流高电压；每对相向喷口喷出分别带相反电荷的纳米纤维，并在空中相互吸引、碰撞形成复合纳米纤维，经牵引、拉伸后形成复合纳米纤维长丝束；第一对相向放置的电纺喷头纺丝形成的复合纳米纤维长丝束向下拉伸，并作为接受体与第二对电纺喷头喷出的分别带相反电荷并相互吸引的纳米纤维在空中相遇，被第二对电纺喷头喷出的纳米纤维包裹，经牵引、拉伸后形成两层复合纳米纤维长丝束；依次类推，最后经导丝辊对(2)牵引、拉伸后得到多层复合纳米纤维长丝束。

Methods 4-Hydroxybenzonitrile (2) as the starting material was transformed to 4-hydroxy-thiobenzamide (3) via thioformylation. And ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (4), which was synthesized via cyclization from 3, was treated with hexamethylenetetramine to generate the intermediate ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (5). The target compound febuxostat (1) was obtained from 5 by etherification, cyanidation, hydrolysis.

以羟基苯腈为原料，经硫代甲酰化得到对羟基硫代苯甲酰胺(3)，3经环合得到2-（4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(4)，4与乌洛托品反应，得到中间体2-（3-甲酰基－4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(5)，之后再经醚化、氰化、水解得到目标产物(1)。

RESULTS: In the 1105 girl students examined, the average interpupillary distance was 59.27mm in the normal eyesight group and 59.35mm in the myopia group, without significant difference by statistical treatment.

结果：1105名受检青年女性中，视力正常组与近视眼组的瞳距均值分别为59.27，59.35mm，两组瞳距比较经统计学处理无差异性存在；眼球突出度均值视力正常组为15.49mm，近视眼组为15.76mm；视力正常眼，轻度、中度、高度近视眼各组人群测定眼球突出度经方差分析比较有显著性差异（F=6.108，P.01），4组人群眼球突出度经LSD处理后两两比较：视力正常眼与中、高度近视眼，高度近视眼与轻、中度近视眼等4组之间均有显著性差异（P.05）；各组眼球突出度左、右眼间比较，差异均无显著性。

Fig 1 Negative control Female umbilical cord sample has no Y-specific signal after in situ hybridization with the biotinylated Y-repeated sequence DNA probe PY3.4 Fig 2 Positive control Flow-sorted male umbilical cord cells hybridized to Y-specific DNA probe PY3.4,Every cell contains a Y-specific signal Fig 3 Fetal cells sorted from maternal blood Flow-sorted cells from a pregnant woman at 20 weeks of gestation hybridized to Y-specific DNA probe PY3.4,containing a Y-specific signal Fig 4 The result of polymerase chain reaction Lane 1:male umbilical cord NRBCs sorted by FITC-conjugated anti-monoclonal glycophorin A;Lane 2:sample of 2;Lane 3:male umbilical cord NRBCs sorted by FITC-conjugated anti-CD36;Lanes 4-5:samples of 1 and 3;Lane 6:50 cells of male;Lane 7:5 cells of male;Lane 8:200ng male DNA(positive+control);Lane 9:nonpregnant female DNA(negative+control);Lane 10:ΦX174 HaeⅢ Maker,271bp:amplified band of Y-specific gene SRY;383bp:amplified band of human β-globin gene

图1 阴性对照女性脐带血标本，经与生物素标记的Y-染色体重复序列DNA探针原位杂交后未见Y-染色体特异信号图2 阳性对照分选的男性脐血细胞经与Y-特异DNA探针杂交后，每一细胞都含有Y-染色体特异信号图3 母体外周血中分选的胎儿细胞从一位妊娠20周的孕妇外周血中分选出的细胞经与Y-特异DNA探针杂交细胞中含有Y-染色体特异信号图4 聚合酶链反应结果 1：GPA-FITC单抗分选男胎脐血NRBCs；2：2号标本；3：CD36-FITC单抗分选男胎脐血NRBCs；4、5：1、3号标本；6：50个男性细胞标本；7：5个男性细胞标本；8：200ng男性DNA；9：未孕女性DNA；10：ΦX174 HaeⅢ标准，271bp：为SRY基因扩增带；383bp：为人β-珠蛋白基因扩增带内参照

There were three major findings.(1) On the basis of the assessment of overall model fit and parameter estimates, the hypothesized second-order confirmatory factor analysis model represented an adequate fit to the sample data.(2) According to the cross-validation analysis, the second-order factorial validity of this scale was very stable.(3) This hypothesized model was invariance across these five important demographical variables, including school, gender, grade, right/left-handedness, and past experience in unintentional injury, via the testing of invariance in the multiple groups.

结果有三项主要的发现：第一、经整体暨个别的残差分析、整体模式之适配与其取代指标，以及估计参数之统计考验等结果，均指出假设此量表为二阶因素分析测量模式是相当恰当的；第二、经交互确认效度分析结果，显示此量表之二阶潜在因素结构是非常稳定；第三、经多组别不变量统计考验结果，指出此量表之二阶潜在因素结构，对於学校别、性别、年级、用手习惯，以及过去伤害经验这些社会人口变项，大致上具有因素个数、因素负荷量、因素变异数，以及测量误差变异数等不变量的特性。

Undergoing elective surgery were randomly divided intothree groups acˉcording to the method of the induction of general anesthesia,i.e GroupⅠ（n=13）:intravenous induction:midazolam0.03mg/kg,fentanyl3μg/kg ,etomidate0.3mg/kg,vecuronium1mg and succinylcholine1.5mg/kg;GroupⅡ（n=13）:orolaryngeal lignocaine spray combined with intravenous induction,lignocaine administered just before the inducˉtion of anesthesia;GroupⅢ（n=13）:epidural block combined with general anesthesia,2%lignocaine3ml adminˉistered via epidural catheter before the induction.

组Ⅰ为单纯经静脉全麻诱导组，麻醉用药为咪唑安定0.03mg/kg、芬太尼3μg/kg 、依托咪酯0.3mg/kg、维库溴铵1mg和琥珀胆碱1.5mg/kg；组Ⅱ为诱导即刻咽喉部喷雾表麻加经静脉全麻诱导组；组Ⅲ为硬膜外阻滞加经静脉全麻诱导组。

Marcellus of Ancyra (Pseudo-Anthimus),'On the Holy Church': Text, Translation and Commentary.

在圣经和大公教会的《信经》，例如《亚他那修信经》和《迦克墩信经》，都申明了这方面的解释。

The new antigen P3 peptide which harvested from the 430A peptide synthesizer were verified by the mass spectrograph and HPLC, that the ratio of mass/charge of the synthetic peptide was equal to the molecular weight in theory and its purity was above 95%. The Western blot analysis show that the antiserum induced by the new antigen plus hemocyanin could bind with the 22KD and 55KD proteins, which were existed in the testis tissue protein of mouse, rat and human.

一、经抗原分子设计，在430A自动肽合成仪上合成的新抗原P3，经质谱仪分析证明其荷质比与理论一致；纯化后，其纯度大于95％；将新抗原与KLH偶连后免疫小鼠，经Western blot证实其诱导的特异性抗体可识别小鼠、大鼠、人睾丸组织中分子量约为22KD和55KD左右的蛋白质。

In Japanese rural districts postmenopausal (6 months or longer since last mense) women were followed for 4 years in order to identify variables associated with bone loss and propose nursing prevention guidelines for osteoporosis which should be based on life-style characteristics.

为了检测妇女绝经后发生骨量减少的相关指标进而倡导依据生活方式的特点对绝经后妇女骨质疏松的发生采取相应的预防和护理方针，我们对日本乡村的绝经后妇女（末次月经后六个月或更长时间算起）进行了为期4a的随访。

The azocyclotin belongs to the medium toxic miticide, the original medicine big mouse acute after mouth LD50 is 76-180mg/kg, acute after skin LD50 is 1000mg/kg, the mouse acute after mouth LD50 is 417-980mg/kg.

三唑锡属于中等毒性杀螨剂，原药大鼠急性经口LD50为76-180mg/kg，急性经皮LD50为1000mg/kg，小鼠急性经口LD50为417-980mg/kg。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。