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细辛脑

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Objective:The purpose of this study was to discuss α-Asarone mechanism of removing sputum.

目的:研究α-细辛脑对气管纤毛运动的影响,探讨其祛痰作用机理。

Objective To establish an HPLC method for the determination of asarone and impurities in asarone injection.

目的 建立测定细辛脑注射液的含量及有关物质的高效液相色谱法。

The method can be used for the quality control of asarone injection.

本法可用于细辛脑注射液的含量及有关物质测定。

Results:The detection limits for asarone were 25 ng respectively.Good resolution for asarone and related substances was obtained.

结果:细辛脑的最低检测限量25 ng,细辛脑与各杂质分离良好。

Objective To study the compatible stability between Asarone injection and Diprophylline injection.

目的 研究细辛脑与二羟丙茶碱注射液配伍稳定性,为临床合理用药提供依据。

Objective To compare the therapeutic effects of asarone injection by aerosol inhalation and intravenous drip in the treatment of bronchiolitis.

目的 比较细辛脑注射液雾化吸入与静脉滴注治疗毛细支气管炎疗效。

They are stable when Asarone injection and Diprophylline injection was mixed.

在室温(25℃)下,细辛脑与二羟丙茶碱注射液配伍后稳定性较好,临床上2药可以配伍使用。

Results Asarone and impurities could be separated well under the condition. Linear calibration curve was obtained in the range of 2~80 mg.L-1 with an average recovery of 100.2%(RSD= 0.37%).

结果 本色谱条件能分离细辛脑及有关物质;在2~80 mg·L-1浓度范围内,细辛脑的峰面积与其浓度呈线性关系,方法平均回收率为100.2%,RSD为0.37%。

Objective To compare the therapeutic effects of asarone injection by aerosol inhalation and intravenous drip in the treatment of bronchiolitis.Methods 53 cases of bronchiolitis in children were treated with asarone injection by aerosol inhalation ,and 47 cases treated with asarone injection by intravenous drip severed as control.

目的 比较细辛脑注射液雾化吸入与静脉滴注治疗毛细支气管炎疗效方法采用细辛脑注射液雾化吸入治疗53 例毛细支气管炎的患儿,并且与该药静脉滴注治疗组47例相比较。

Methods The UV method for determination of asarone and diprophlline in their mixed solution was established, by which they were assayed when the mixed solution was set at 24 during 6h.

细辛脑、二羟丙茶碱加入葡萄糖注射液中,混合均匀后,建立细辛脑与二羟丙茶碱混合液紫外分光光度法含量测定方法,分析混合液在室温下(25℃)8 h内2药含量,并观察其pH值、外观、微粒及紫外光谱及峰形变化。

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