细菌感染

A acute partial obstructive hepatocholangitis model by selective ligation and injection of E coli into left hepatic bile duct was successfully founded in rat. Using parameters including mortality, mitochondrial glutamic oxalacetic transaminase and ornithine carbamoytransferase activity, pathological observation and blood culture of bacteria, we evaluated the model.

作者采用选择性左肝管穿刺注菌法成功地建立了Wistar大鼠急性部分肝胆管梗阻感染的脓毒症模型，并从胆管系统形态学、累计病死率、血清线粒体谷草转氨酶和鸟氨酸氨基转移酶活性、多器官大体病理观察以及血液细菌培养几方面对该模型的科学性、重复性进行了评估。

Through the examinations of the diseased eels by parasitological, bacteriological and virological methods and the artificial infection test, the pathogen of the eel "mad swim disease" was fully confirmed to be eel coronavirus like virus.

对近两年在我国福建省等地养殖的鳗鱼暴发流行的一种不明病因的疾病，通过寄生虫学、细菌学、病毒学检查，以及人工感染回归试验，确认其病原为鳗冠状病毒样病毒。

The most common microbes causing infections in percutaneously inserted uncuffed catheters are, in order of prevalence, coagulase-negative staphylococci, Staphylococcus aureus, Candida species, and enteric gram-negative bacilli.

根据患病率的高低，引起经皮插入的无气囊导管感染的最常见的微生物排序如下：凝固酶阴性葡萄球菌、金黄色葡萄球菌、念珠菌属菌种和肠道革兰氏阴性细菌。

Both Pseudomonas and Pantoeu universally exist on Bursaphelenchus xylophilus in diseased pines, and there is selectivity for pine wood nematodes to carry bacteria. Bioassay results show that both strains of Pseudomonas and Pantoea are phytotoxin producers.

由此可知，假单胞菌和泛菌分布较广，在所有采样疫区感染松材线虫病的马尾松和黑松病死木中都能分离到，是普遍存在病木组织中松材线虫携带的主要细菌。

Due to prickly heat, children often not the main hand scratch so easily into the skin of bacteria in the small porokeratosis, caused by infection, inflammation.

由于痱子刺痒，小儿常不由主地用手搔抓，这样就容易将细菌带入皮肤小汗孔里，引起感染﹑发炎。

20 Centuries 60 time, american Gristina put forward, all biology material are embedded inside body hind, its surface all can form a kind of biomembrane, bacterial criterion is many in this kind of biomembrane progenitive, the many mucilage outside producing a cell is qualitative (Extracellular Slime Substance, ESS), it is the easy hair sex that causes false body infection and the main factor that study a gender hard.

概要： 20世纪60年代，美国Gristina等提出，所有的生物材料植入体内后，其表面均能形成一种生物膜，细菌则在这种生物膜中大量繁殖，并产生细胞外多粘质物质(Extracellular Slime Substance，ESS)，是导致假体感染的易发性和难治性的重要因素。

Organisms culture included: 5 Staphylococcus aureus, 2 methicillin-resistant S. aureus, 5 non–S. aureus, 5 Propionibacterium acnes, 3 Escherichia coli, 2 Enterococcus,2 Enterobacter, 2 Protes in 2 patients each.

细菌培养的结果为：5例出现金葡菌；2例出现耐青霉素金葡菌；5例非硫金葡菌；5例短棒杆菌；3例大肠杆菌；2例肠道球菌；2例肠杆菌；2例真菌感染。

The pathologic changes of fungal diseases in alimentary canal were tissue necrosis, ulcer formation and pseudomembranous inflammation.

其病变为消化道组织坏死、溃疡形成及假膜性炎症；炎细胞浸润不明显，且以单核细胞浸润为主；假膜性炎中有较多的中性粒细胞渗出，可能与某些细菌的混合感染有关系。

Second, residues in the reactive site of the inhibitor were replaced by the consensus substrate recognition sequence of furin, namely, Arg at P_1, Lys at P_2, Arg at P_4 and Arg at P_6. In addition, the P_7 residue Asp was substituted with Ala to avoid possible electrostatic interference with furin inhibition. Finally, the extra N and C terminal residues beyond the doubly conjugated disulfide loops were further truncated. However, all resultant synthetic peptides were found to be temporary inhibitors of furin and kexin during a prolonged incubation, with the scissile peptide bond between P1 and P'1 cleaved to different extents by the enzymes.

高活性、低分子量的furin酶抑制剂有可能发展成为新型的抗细菌内毒素和抗病毒感染的药物，我们以绿豆胰蛋白酶抑制剂Lys片段长链22肽为模板，设计了一系列能抑制furin和kexin活性的突变体，采用如下三种方法逐步优化：一、去除Lys片段长链三对二硫键中的一对，用Ser替换Cys，减少可能存在的二硫键错误配对；二、抑制剂的活性中心根据furin底物的专一性逐步改变，即P1、P2、P4和P6位分别变为Arg、Lys、Arg和Arg，同时为了避免P7 Asp和P6 Arg之间可能存在的相互作用，将P7位Asp替换为Ala；三、将两对二硫键形成的双环的外面5个氨基酸残基去除。

Microscopic parasites include single-celled protozoans such as amoebas and sporozoa, fungi, and bacteria, which can infect animals and plants.

显微镜下可见的有单细胞原生类寄生虫，例如阿米巴和孢子虫，真菌及细菌，这些均能感染动物及植物。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。