细胞趋性的

Objective:To assess the important role of chemokine receptor CCR4 and CXCR3 in patients with atopic dermatitis.

目的为研究特应性皮炎患者外周血趋化性细胞因子受体CCR4和CXCR3在特应性皮炎的发病过程中的作用。

Some cells also exhibit chemotaxis, the ability to move toward or away from the source of a diffusing chemical.

一些细胞还表现出趋化性，可以趋向和远离扩散的化学源。

The following methods were used in the study, such as viral inoculation of animal, pathological method, flow cytometry, RT-PCR, in situ hybridization, immunohistochemistry and terminal deoxy nucleotidyl transferase mediated dUTP nick end labling. Morphological changes of the infected chickling, dynamic changes of T, B cells and T subsets, changes of adhesion molecules on the lymphocyte surface, necrosis and apoptosis of lymphocyte and neurons, changes of MIP-1β and IL-8 producing cells in the brain, cell types of perivascular tuffing in cerebral tissue were systematically studied. The key research results were.(1)The average percentage of CD19+cell in blood, bursa and spleen, after 3, 5 days of inoculation, was significantly Phybridization revealed that the number of IL-8 and MIP-1βproducing cells was increased in the infected brain.

在研究过程中，采用了病毒接种技术、普通病理学研究方法、流式细胞仪技术、RT-PCR技术、原位杂交技术、免疫组化技术、凋亡细胞末端标记技术，系统研究了不同日龄的SPF雏鸡人工感染AEV-NH937株后的病理变化，T和B淋巴细胞、T淋巴细胞亚群的动态变化规律，淋巴细胞表面某些粘附分子的变化，淋巴细胞和神经元的坏死与凋亡，雏鸡脑组织中产生趋化因子MIP-1β和IL-8细胞的变化规律，脑组织中围官性细胞浸润的细胞类型。

B. The expression of chemotaxis cytokine and infiltration of inflammatory cell can be relieved by the warm and purgation method in acute period.

温下法在急性期可以通过减少趋化性细胞因子的表达减轻炎细胞的浸润。

Severe complications arising from influenza virus infection （pandemic influenza or the highly pathogenic avian H5N1viruses） are often associated with rapid, massive inflammatory cell infiltration, acute respiratory distress, reactive hemophagocytosis and multiple organ involvement.

流感病毒感染（如暴发性流行或高致病性禽流感H5N1感染）可以造成广泛的病理损伤及严重的并发症，其肺部病理损伤以肺水肿及广泛的炎性渗出为特点，并伴有人量的中性粒细胞、巨噬细胞、淋巴细胞浸润及促炎因子和趋化因子的产生。

Whether there are differences in the expression of the principal cytokines and chemokines relevant to eosinophilic and neutrophilic inflammation in the airway tissues of severe compared to moderate asthmatics has not been determined.

然而在中度和重度哮喘气道内组织，与嗜酸细胞和中性粒细胞性炎症相关的主要细胞因子和趋化因子的表达是否存在差异现在还不明确。

PTX at tenuates the ALI induced by LPS or sepsis in rat. The therapeutic effects of PTX include:improve oxygenation, at tenuate pulmonary edema formation, enhance animal survival in sepsis-induced ALI. The mechanisms may related with the effects of PTX inhibiting the chemotaxis, migration, activation of inflammatory leukocytes, diminishing the production of active oxygen, and inhibiting inflammatory cytokine release partly.

4PTX对大鼠内毒素性ALI及脓毒症性ALI均有一定的防治作用，主要表现在改善动脉血氧合，减轻肺水肿形成，提高脓毒症性ALI大鼠的存活率等方面，其机理可能与抑制白细胞趋化与激活，减少肺内白细胞渗出及活性氧产生，一定程度上抑制炎性细胞因子生成等有关。

Titres of neutralization antibody induced by DNA immunization were correlated to efficacy of protective immunity.

目的探讨细胞因子及趋化性细胞因子在结核患者保护性免疫中的作用。

In histopathology sections showed that alveoli were complete and clear with walls being thin and brittle. In experimental group, some petechia were observed in lung samples , the area of fibroblast and fibrinogen in histopathology sections were found , and the ground-glass predominance and reticulation structure in Micro-CT findings were increased during the period from the 1st week to the 3rd week, and degrade in the 4th week after the administration.

结果显示，控制组之肺脏检体色泽正常，没有出血，组织病理学则以I型肺泡细胞为主，无间质性肺炎且肺泡完整清净，肺泡壁薄而完整；实验组方面，第一~三周肺脏检体外观及组织病理的呈现出血点及出血病灶且越趋严重，第四周则消退，且Micro- CT影像评估亦相同。

Our data suggest an important role of CXCR3 in the development and advance of psoriasis vulgaris.

趋化性细胞因子受体CXCR3可能在银屑病的发病中起重要作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。