细胞色素

Effect: The nature is temperate, eliminates remnant make-up and the dirt effectively, and can decompose the cytochrome to be calm, desalinates the spot.

功效：性质温和，有效清除残妆及污垢，并能分解细胞色素沉着，淡化斑点。

Chemist Sid Nelson, Ph.D., and colleagues, of the University of Washington in Seattle, tested the effects of acetaminophen and caffeine on E. coli bacteria genetically engineered to express a key human enzyme ( cytochrome P450 3A4 ) in the liver that detoxifies many prescription and nonprescription drugs.

化学家学会纳尔逊博士和同事，在西雅图华盛顿大学的，经测试的影响，对乙酰氨基酚和咖啡因对大肠杆菌基因工程表达的一个关键人力酶（细胞色素p450 3a4 ）在肝脏中说， detoxifies许多处方和还敦促毒品。

A nanoelectrospray interface was set up for hyphenating with orthogonal injection time-of-flight mass spectrometer.

研制了纳喷雾离子化技术与正交飞行时间质谱的联用接口，在电场力的作用下，样品流速约为30nL/min，40nmol/L细胞色素c溶液的单张图谱样品消耗量为0。

The average percent value of G C (49.3%) was less than that of A T (50.7%), there was a bias of the content of G, T in the third codon; The number of transition G-A and T-C were 22, 15 respectively, which were higher than that of transition A-G and C-T, the number of tranversion C-A, T-G is 2 respectively, and other tranversion patterns didnt occur; the probability of transition was higher than that of tranversion , Ts/Tv = 9.5-19, there was the highest number of transition in the third codon. The gamma parameter a of the lst,nd and 3rd codon positions were 0.00572,0.01237 and 1.05239 respectively, they showed that there was adifferent substitution rate at different codon position. Frequences of synonymous codon usage were relatively biased. The average rates of synonymous and nonsynonymous substitution were 0.0787, 0.0011 respectively, there was a significant difference between dS and dN (Z = 4.713, p.01), and the low ratio( CD = 0.0284 .3) of dN/dS ratio impled that there were selective constraints against the nonsynonymous sites in cyt-b gene, The distribution of nonsynonymous codon substitution pattern related to Grantharm distance indicated that the purified selection at 2nd codon positions was more intensive than that at 1st codon positions. The phylogenetic trees supported the view of the double origin of Chinese goose, which means that domestic Chinese goose was derived from Anser cygnoides and domestic European goose, and Yili was derived from Anser anser.

碱基含量分析可知，序列的G C含量(49.3％)＜A T含量(50.7％)，密码子第三位点的G、T含量都有较强的偏倚性；序列间G→A和T→C的转换数(22次和15次)高于A→G和C→T的转换数(10次和9次)，C→A、T→G颠换数均为2次，其余颠换模式均未发生；转换数明显高于颠换数，Ts／Tv=9.5～19，密码子第三位点的转换数最高，呈现了相当强烈的转换偏倚性；密码子第一、二和三位点的gamma分布参数α值分别为0.00572、0.01237和1.05239，表明密码子第一位点的替换速率变异最大，第二位点次之，第三位点的替换速率变异相对较小；编码同一氨基酸的同义密码子并非随机使用，表现出一定程度的使用偏倚性；同义替换速率和非同义替换速率分别为0.0787和0.0011，dS与dN值间的差异极显著(Z=4.713，p＜0.01)，而ω=0.0284，明显小于0.3，表明雁属鹅细胞色素b基因序列经历了中度净化选择作用；单步非同义替换(Sing-step nonsymonymous codon substitution，SSNCS)分布模式与Grantharm距离之间的关系说明密码子的三个位点所受的净化选择强度不同；构建的最大简约树与邻接树拓扑结构一致，支持中国家鹅的双起源学说，即除伊犁鹅外的其它中国鹅品种起源于鸿雁，伊犁鹅和欧洲的郎德鹅、莱茵鹅起源于灰雁。

Cytochrome P450 2D6 is a highly polymorphic enzyme in the human. It mainly metabolizes cardiovascular drugs and antipsychotic drugs.

细胞色素P450 2D6是最有多态性的酶系，主要参与心血管药物、抗精神病药物等的代谢。

The results showed that the partially folded chicken heart apocytochrome c has a highly dynamic hydrophobic core and also tends to aggregate, which is consistent with its folding tendency.

结果表明，部分折叠的鸡心脱血红素细胞色素c分子获得了一种高度动态的结构，形成了动态的疏水核心；同时，它也具有较强的凝集倾向。

First, chicken heart apocytochrome c with different unfolded states were further characterized, with the partially folded state possessing some characteristics of protein folding intermediate-"molten globule"-it contains significant secondary structure, with a highly dynamic hydrophobic core, and strongly tends to aggregate.

首先，对鸡心脱血红素细胞色素c的不同解折叠状态进行了较深入的研究，表明其部分折叠的状态具有蛋白质折叠中间态&molten globule&的性质：它具有相当的二级结构，形成了高度动态的疏水核心，并进行有很强的凝集倾向性。

Acceptable resolutions were achieved when it was applied for the separation of dipeptides including Leu-Tyr and Val-Tyr by using 1-butanol-acetic acid-water (4:1:5, V/V/V) solvent system. The proteins including cytochrome C and myoglobin, lysozyme and myoglobin, and fresh chicken egg-white proteins were well separated by 12.5% PEG1000-12.5% K2HPO4-75% water (pH 9.0) and 16% PEG 1000-12.5% K2HPO4-71.5% water (pH 8.0) system.

应用研究表明，采用正丁醇-醋酸-水(4：1：5， V/V/V)和PEG1000-磷酸钾盐-水(12.5：12.5：75， W/W/W)(pH 9.0)体系可以在较高的流动相流速和较高的固定相保留下分别实现对亮氨酸-酪氨酸和缬氨酸-酪氨酸二肽混合物以及细胞色素C与肌红蛋白、肌红蛋白与溶菌酶混合物及鸡蛋清样品中蛋白成分的成功分离。

The expression of cytochrome P450 3A (CYP3A) subfamily implicated in drug metabolism in human fetal adrenals and livers was detected by using enzyme assays and the reverse transcription polymerase chain reaction.

采用酶学和逆转录聚合酶链式反应技术，研究与药物代谢密切相关的细胞色素P450 3A( CYP3A)在胎肾上腺和胎肝中的表达。

Key words: cytochrome P450;flunixin meglumine;dapsone;chlorzoxazone;pig

细胞色素P450；氟尼辛葡甲铵；氨苯砜；氯唑沙宗；猪

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新