细胞膜

On the morphological differentiation,by inducing of fetal calf serum,it wasshown that the cytotrophoblast cells underwent aggregation first,and the adjacentcytoplasm membranes became tightly contacted through desomosomes andcytoskeleton.Then the adjacent cytoplasm membranes disintegrated fragmentallyto form fusion pore-like structure.Finally the multinuclear cells formed and inwhich the intercellular desmosomes disappeared.Immunocytochemical stainingfurther demonstrated that the formation of syncytium was through cell membranefusion rather than the amitosis process.

细胞形态分化的研究结果表明：早孕胎盘来源的细胞滋养层细胞在血清诱导下，首先发生聚集，并通过桥粒和细胞骨架使相邻的细胞膜紧密接触；之后细胞膜发生片段断裂，形成融合孔样结构；细胞间桥粒消失，最终形成多核的合体细胞；免疫细胞化学分析进一步证实合体化是通过细胞膜融合而非无丝分裂（amitosis即细胞核分裂而细胞质不分裂）实现的。

The protein and phospholipid constituent in membrane of neurocyte in brain of chicken with encephalomalacia was separated and studied with the method of SDS-PAGE electrophoresis and the method of high performance-thin layer chromatography respectively The fluidity of neurocyte membrane of chicken with encephalomalacia was determined for the first time The content of Ca and trace elements were determined in chicken encephalomalacia systematically and the status of Fe ion in cerebellum was observed. The activity of enzymes that were relative to metabolism of energy and neuro-medium in brain were checked systematically with the method of enzyme-histochemistry. Pathological examination was carried out by microscopic and ultramicroscopic observation. The apoptosis of neurocyte in brain was checked.

在进行临床观察、定期剖杀并检测体内V〓含量、体重和脑重的基础上，重点研究了与神经损伤有关的以下几个方面的内容：系统地检测了体内自由基代谢和抗氧化系统功能的变化；首次采用SDS-PAGE电泳法分离并检测了雏鸡脑软化症神经细胞膜蛋白组分，并以高效薄层层析法检测神经细胞膜磷脂组分；测定了脑软化症雏鸡神经细胞膜的膜流动性；首次系统检测了脑软化症雏鸡体内钙及微量元素含量，并进行了小脑组织总铁离子状态观察；采用酶组织化学方法系统地观察了脑组织中与脑能量代谢和神经递质有关的酶的活性；对相关组织进行了病理组织学和超微结构观察；并对脑组织中神经细胞的凋亡进行了检测。

Pike protein consists of S1 and S2 subunit. S1 is head and S2 is rod-shape part, intermolecular effort can bind each other. S1 can bind with host cell epimembranal acceptor. S2 can fix integral Spike protein on the cellular membrane and mediate cell-fusion with virus and host cell. There are significant antigen determinant of virus in Spike protein, genic heterogenesis can effect viral pathogenicity. SARS-CoV Spike protein, which has 23 pieces larvaceous glycosylation sit, consists of 1256 amino acid. Its N-terminals and C-terminals is corresponding conservative.

蛋白是I型膜糖蛋白，介导病毒与宿主细胞膜上的受体结合并与宿主细胞膜相融合。S蛋白由S1和S2两个亚基组成。S1形成球状部分，S2形成棒状部分，两者之间通过分子间的作用力相互结合。S1能与宿主细胞上的受体结合，S2可把整个S蛋白固定在细胞膜上，并介导病毒包膜与宿主细胞膜融合。S蛋白上有重要的病毒抗原决定簇，S基因的突变会影响病毒的致病性。

Chlorotic spot whitening, regulating the "three high"-linolenic acid is an essential component of human cell membrane material, one can improve the ratio of fat cell membrane, increasing membrane permeability, and promote cell metabolism, they are partial pigmentation of the Scavenging is particularly evident; also because of its strong anti-oxidation, plaque will not relapse back.

褪斑美白，调节&三高&α-亚麻酸是人体细胞膜的基本组成物质之一，能够改善细胞膜上的脂肪比例，增加细胞膜的通透性，促进细胞代谢，故而对局部色素沉淀的清除作用尤为明显；又因其具有很强的抗氧化作用，斑退后不会复发。

Results The expression of ADAM19 are mainly in the cell membrane, plasma and column of cytotrophoblast; The expression of ADAM19 is mainly located on cytotrophoblast during first trimester of pregnancy, and on syncytiotrophoblast in second and third trimester.

结果ADAM19的表达主要集中在滋养细胞的细胞膜、细胞质中和细胞滋养层柱细胞中；早孕绒毛中，ADAM19表达主要集中于细胞滋养细胞膜，在晚孕期胎盘，ADAM19主要表达于合体滋养细胞膜。

The hypercholesterolemic rats were selected to imitate early stage of human atherosclerosis The effects and mechanism of n-3 PUFA on endothelium were investigated with the following parameters: the morphological appearance and arrangement of endothelium stained by Ag, in vitro endothelium-dependentrelaxation of aortic ring, endothelial permeability test using Even′s Blue, blood lipid and body weight in one-week intervals, excitative and emissive spectrum of RBC membrane labeled by DPH (1, 6-Diphenyl-1, 3, 5-hexatriene), fluidity of RBC membrane, plasma and RBC membrane LPO

在整体和离体水平，选用大鼠高脂血症模型模拟动脉粥样硬化早期状况。用114只大鼠多指标着重研究n-3多不饱和脂肪酸在高脂血症状态下对内皮的保护作用，以探讨其预防动脉粥样硬化的机理。所采用指标包括：浸银法观察内皮细胞排列与形态；离体血管环观察内皮依赖性舒张；伊文氏蓝染料法观察内皮通透性。为探讨作用机理，进行了血脂和体重的动态监测、DPH(1，6-二苯基-1，3，5，乙三烯)标记红细胞膜的荧光光谱测定、红细胞膜流动性测定、血浆和红细胞膜脂质过氧化物测定。

RESULTS: The results showed that the water extract of phellodendron and one of its main components increased the cell membrane fluidity in the inactive state, but the other two components, berberine and jatrorrhizine, decreased the cell membrane fluidity.

结果：在无ConA刺激时，黄柏的水提物可提高小鼠脾细胞膜的流动性，6.25%的浓度与对照组相比有极显著性差异；小檗碱与药根碱可降低脾细胞膜的流动性，与对照组相比均有显著性差异；巴马汀可提高脾细胞膜的流动性，与对照组相比有极显著性差异。

RESULTS: The results showed that the water extract of phellodendron and one of itsmain components increased the cell membrane fluidity in the inactive state, but the other two components, berberineand jatrorrhizine, decreased the cell membrane fluidity.

结果：在无ConA刺激时，黄柏的水提物可提高小鼠脾细胞膜的流动性，6.25％的浓度与对照组相比有极显著性差异；小檗碱与药根碱可降低脾细胞膜的流动性，与对照组相比均有显著性差异；巴马汀可提高脾细胞膜的流动性，与对照组相比有极显著性差异。

In the presence of linoleic platinum the ratios of W and S of breast cancer cell membranes and S180 cell membranes labeled with MSL were changed, The results indicate linoleic platinum can react with mercapto groups on the proteins of tumor cell membranes and change the conformations of cell membrane proteins.

亚油酸铂靶向脂质体的存在，使MSL的乳腺癌细胞膜和S180实体瘤细胞膜的W和S的比值发生了变化，结果表明亚油酸铂可以作用于癌细胞膜影响膜蛋白巯基结合部位，并使癌细胞膜表面蛋白质构象改变。

Interaction of TNT with intact human erythrocytes leaded to depletion of GSH. drop of ghost SH and obvious inhibitions of 〓-ATPase and 〓 active transport. However, exposure of inside-out vesicles without Hb to TNT did not show observable change of 〓 active trans- port, suggesting that the presence of Hb is necessary for TNT to disrupt 〓 transporting function of erythro- cytes.

TNT与完整的人红细胞相互作用后，细胞内GSH水平和红细胞膜SH含量均有不同程度的下降，与此同时，红细胞膜〓-ATPase活性和〓主动转运过程均有显著的抑制，但TNT与去除血红蛋白的膜翻转泡（inside-out vesicle）孵育，则红细胞膜〓主动转运未发生明显变化，表明TNT对红细胞膜〓主动转运的抑制作用须以〓的存在为前提。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。