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RESULTS: Similar to the control, the cells in Jagged1 group displayed irregular shape with spiny or sheetlike dendrites and the cellular surface was rough. In contrast, the cells in DAPT group exhibited little dendritic processes and most of them were of round shape and with smooth surface.

结果: 与对照组相似, Jagged1组的细胞形态不规则,伪足分化和突出的片状结构较为明显,且表面粗糙;相反, DAPT组细胞的伪足不明显,多数细胞趋于圆形,表面相对光滑。

The histopathology showed that the tumors were rich in cells arranged in fascicles with bipolar and spindled processes. The nuclei showed minor pleomorphism. A few tumor cells were centered on the vessels with a nuclear-free zone that was characteristic of ependymoma.

病理组织学上肿瘤富于细胞,排列成束状、交织状,细胞胞突细长双极,核异型性小,少数肿瘤细胞围绕血管周围形成室管膜瘤的无核区结构。

Results As compared with control group,the bone trabecula was thinner in experiment group,and the bone structure was rarefaction and disorder, with less bone mass.

结果 与对照组比较,实验组骨小梁纤细,结构稀疏紊乱,骨量少,部分骨小量断裂,成骨细胞和破骨细胞数量均增多,骨陷窝内破骨细胞活跃;骨密度下降。

Cytomorphology changes occurred obviously in cultured neurons such as cell edema, cell atrophy, etc."Jiu Nao Ning"Injection could improve the activity, decrease the transudation rate of LDH and the apoptotic rate. It could also increase the contents of DNA, RNA and improve the pathologic changes in cultured neurons.

救脑宁注射液高、中、低剂量组,在各时间点表现出不同程度地提高细胞代谢率、降低LDH漏出率和凋亡率的作用,与模型组比较p<0.05;同时也显示出改善细胞形态学异常变化、增加细胞内DNA、RNA含量,保护神经细胞功能与结构免遭损伤等作用,以中剂量效果最好,其与清开灵的药效作用相比,要么相似要么更佳。

The hepatocytes which were injected into thymus could survive more than 2 weeks after injection and appeared to be irregular hepatic cells cords and sinusoid in shape, and severe vacuolar degeneration in 3 weeks.

本实验在未用任何免疫抑制剂的情况下,肝细胞胸腺内注入后1周、2周,显微镜下见植入胸腺内的肝细胞已生长出不规则的肝索及肝窦样结构。3周时的胸腺内植入的肝细胞仍存活,但空泡变性明显。

The cells were then maintained in culture flasks and further identified by immunofluorescence,immunocytochemistry,and vasculogenesis experiment.

结果兔外周血单个核细胞体外培养可成功获得内皮祖细胞,稳定表达内皮祖细胞相关抗原,并能在matrigel凝胶上形成稳定的血管腔样结构。

The reacting tite with NDPK-A was 1:800 and theantisera was specific.Conclusions: The purified rhNDPK-A protein exists mainly in the form of hexamer;rhNDPK-A protein can promote the survival of spleen cell and may take part in theadjustment of cell growth by the way of changing cell cycle.

ELISA法检测所制备的抗体的反应效价为:1:800,western blotting试验结果证实,该抗血清具备较好的特异性,能与rhNDPK-A蛋白发生反应,结论:rhNDPK-A蛋白可能主要以六聚体形式存在,直接观察的蛋白结构与文献报道的X衍射结果相似;rhNDPK-A蛋白对正常小鼠的脾细胞的存活有促进作用,推测很可能以信号转导的方式调控细胞周期从而达到对细胞生长的调节作用。

A human MDRl full length cDNA probe was used to screen a pufferfish cosmid library and nine clones, which would contain the whole MDR gene family in the pufferfish genome, were finally identified. One of the cosmid clones was sequenced. Sequence analysis revealed that there would be at least three MDR homologues in the corresponding region.

其表达产物为一跨膜蛋白p-glycoprotein,通过ATP提供能量,将进入细胞内的多种物质泵出细胞外,从而使细胞对这些物质产生耐药性,多药耐药基因的功能决定了它在肿瘤化疗中的位置而使其成为基因结构、功能和表达、调控研究中的热点。

In a-bout one third cells agglomerate chromatin localizes at the edge of nucleus, which shows apoptotic traits.

PCF处理的HaCaT细胞的超微结构损伤程度明显减轻,如胞浆内更少的空泡样结构和更多形态正常的细胞器,少见具有凋亡形态的细胞,未见凋亡小体等。

The cerebellum of ZDpups had a decreased nember of granular cells in the internal granular cell layer, and dendritic development of basket, stellate and purkinje cells was impaired.

形态学的研究发现哺乳期母鼠锌缺乏可使其仔鼠小脑粒细胞数减少;蒲肯野细胞、兰状细胞及星状细胞的树突分枝减少、突触结构异常。

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