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细胞结构

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Summary: In this study, the change of adhensive struture, adhensive moleculd and actin filament in K-ras gene transfected pulmornary fibrocyte of mice, and the mechanism of invasion and metastasis of cancer cell were investigated by molecular biological techniques.

小结:本研究利用分子生物学技术,探讨K-ras基因导入的鼠肺纤维细胞—恶性转化细胞的粘附结构、粘附分子和肌动蛋白的改变,旨在探讨肿瘤细胞的浸润转移机制。

The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop.

间叶细胞胚胎的中胚层部分,由生长于胶状基质的、结构松散的、无特定功能的细胞组成,这些细胞将会发育成结缔组织、骨、软骨、血液及淋巴系统

Under transmission electron microscope, cellular swelling in brain tissue, nuclear membrane of neuron has incisures, some chromatic agglutination, group A mainly appears endoplasmic reticulum distention and glial cell endocytosis, while group B mainly appears histolysis; cardiac fibrous structure is chaotic, Z line concentrates, mitochondria swelling, nucleus deform; the ecphyma of podocyte becomes thinner and longer like villus, some mix together, plasma membrane infolding of renal cells decreases, mitochondria malformation, cells in lumens.

透射电镜观察显示,试验组动物脑组织细胞肿胀,神经元核膜出现切迹,部分染色质凝集,A组动物出现内质网扩张及胶质细胞吞噬现象,B组动物以组织溶解为主;心肌纤维结构紊乱,Z线聚集,收缩带形成,线粒体肿胀,核变形;肾小球足突细长,绒毛化,并可见足突融合,肾小管上皮细胞质膜内褶减少,线粒体畸形,管腔可见脱落细胞,上述改变均以B组为著。

In currence, se- GSH- PX activity have been been used as a standard of Selenium nourishment, GSH- PX is an extremely important protection enzyme in anti oxida- tive defend system of organize and cell of animal.It clear hydroxy radical and hyperoxide in cell respir- ation metabolism reaction ,thereby, mai- ntain cell's normal physiological function, prote- ct biomembrane and biomacromolecule from oxidative damage.If the activity is high or not, effect the ab- ility that the organize clears hyperoxize lipi- d ,directly.

目前,含se-GSH-PX活性已被作为se营养状况可一个指标,该酶是动物组织细胞抗氧化防御系统中一个极为重要的保护性酶,它是以还原型GSH为底物的谷胱甘肽参与的过氧化反应,清除细胞呼吸代谢反应过程产生的羟自由基和过氧化物,从而使细胞能维持正常的生理功能,保护生物膜和生物大分子结构免受氧化损伤。

Results: The pulmonary artery wall of RHD group become more incrassate than that of the control group.

结果:RHD患者肺动脉的结构发生明显改建,RHD及对照组肺动脉内都有增殖与凋亡的细胞,但RHD组增殖细胞多而凋亡细胞明显减少。bcb2在RHD组中表达强度明显高于对照组,而bax在对照组中的表达高于RHD组。

In contract, the tumor tissue of control group kept morphology, tumor nodules composed of undifferentiated carcinoma, and some karyokinesis could be seen, some spotty necrosis were found occasionally in where the structure among tumor cells were loose associated very slight inflammatory response; At the 21 days after injected AdCMVIL-12, the tumor boundary of AdCMVIL-12-Ⅰ group were clear and felt hard by touch, section showed grey.

同期的对照组绝大多数肿瘤细胞形态完好,排列紧密,由大量未分化的肿瘤细胞组成并可见多个核分裂像,偶尔可见散在的点状坏死灶,瘤细胞之间结构松散,炎症反应很轻;AdCMVIL-12注射后第21天时,AdCMVIL-12-Ⅰ组的肿瘤组织经手摸感觉瘤体境界清楚、发硬,切面呈灰白色。

Results An adequately cellular cervical cytology smear,the reduce of cells overlay, the integrality of cells morphology, the clear structure of cells and unconspicuous phenomenon of dissolving and cell shrinkage were observed , the cells were stained well and flamboyantly, the contrast ration was outstanding between cytoplasm and nucleu, the cytoplasm, nucleus,karyosome,and other components were easy to be resolved, the cells boundary,transparence showed clearly.

结果:涂片的细胞量充足,重叠减少、形态结构清晰,无皱缩自溶现象,着色良好,色彩艳丽,浆核对比突出,胞质、核染色质、核仁和其他细胞成分易于识别,细胞境界清楚,透明度良好。

Several masses of condensed chromatin without nuclear membrane were observed in some treated K562 cells,while chromatin of some other cells tended to marginate in crescents around the nuclear envelope with compacting cytoplasm,normal or slightly expanded endoplasmic reticulum,which presented typical morphology of apoptosis.

电镜下,加药处理组中部分细胞染色质凝集成块,没有核膜包被,部分细胞染色质靠核膜边集呈新月形,胞浆浓缩,内质网结构正常或有扩张,呈现典型的凋亡细胞形态。

The part of the embryonic mesoderm, consisting of loosely packed , unspecialized cells set in a

间叶细胞胚胎的中胚层部分,由生长于胶状基质的、结构松散的、无特定功能的细胞组成,这些细胞将会发育成结缔组织、骨、软骨、血液及淋巴系统

Above all,there are some obvious differences among species in distributive density of oil cells, in distribution places of oil cells and mucilage cells and in their sizes. Those structural characteristics are significant for the classification of Lauraceae.

因此,叶片内油细胞的分布密度、油细胞和粘液细胞的分布位置及其大小在种与种之间存在明显的差异,此种结构特征具有分类学上的意义。

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