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细胞结构

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(1) In common cavity malformation, in addition to the abnormal bony labyrinth such as the cochlea, vestibule and lateral semicircular canal, the inner ear perceptive organ such as the saccule, utricle and scala media were also abnormal.(2) Though we could not identify the basal membrane and sensory epithelia under micro-endoscopy, the utricle and saccule could be clearly identified.(3) During cochlear implantation in common cavity malformation, electrode insertion should be monitored under micro-endoscopy, the electrodes should be put close to the anterior wall of the cavity, otherwise the vestibular organ may be damaged.

(1)共同腔畸形极重度聋患者不仅前庭、外半规管和耳蜗的骨性结构形态发生了变化,而且腔内耳蜗中阶与前庭的球囊、椭圆囊的膜迷路结构形态也发生了变化;(2)微窥镜下分辨不出基底膜或听神经细胞的形态结构,可见畸形前庭的球囊、椭圆囊的囊性结构;(3)进行共同腔畸形人工耳蜗植入手术时,应在耳蜗内镜的监视下,将电极摆放到准确位置,尽可能贴近共同腔的前壁,不应损伤前庭器官。

The locomotory apparatus that emerges during the spermiogenesis consists of the multilayered structure, basal bodies, flagella and accessory structures.

精子发生过程中形成的运动器的各部分结构包括鞭毛、基体、多层结构及附属结构;基体是细胞中新形成的结构,在不同类群的蕨类植物中分别由双中心粒、分支生毛体和生毛体产生。

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.

WD40域,在真核蛋白质的数量发现,涵盖了包括各种功能适配器/信号转导,mRNA前体细胞骨架组装加工和管理模式;通常包含一个从11月24日生长激素肽的N残留端和西部数据肽在其C端和40残留长,因而得名WD40;介于生长激素和WD一个保守的核心,作为一个稳定的螺旋桨式平台,可以绑定的蛋白可以稳定或可逆,形成了一个螺旋桨式与每个刀片是一个四叶片结构组成若干链反平行的β-片;与数份检测实例假设,形成了聚大结构,每个WD40重复序列形成了前三个一个刀片和绞线的最后在未来的刀片链,最后C -末端WD40重复完成了第一WD40重复叶片结构,创造螺旋桨的封闭环结构,对螺旋桨顶部和底部表面残留的建议,配合和其他蛋白质的相互作用/或小配体; 7重复副本,目前这条路。

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.

WD40域,在真核蛋白质的数量发现,涵盖了包括各种功能适配器/信号转导,mRNA前体细胞骨架组装加工和管理模式;通常包含一个从11月24日生长激素肽的N残留端和西部数据肽在其C端和40残留长,因此得名WD40;之间的生长激素和WD是一个保守的核心,作为一个稳定的螺旋桨式平台,可以绑定的蛋白可以稳定或可逆性;形式与每个刀片是一个四叶片组成的几个类似结构的螺旋桨,搁浅反平行β-负债表;很少检测副本实例假设,形成了聚大结构,每个WD40重复序列形成了前三个链的一个刀片,并在未来的刀片上链,最后C -末端WD40重复完成了第一WD40重复叶片结构,创造螺旋桨的封闭环结构,对螺旋桨顶部和底部表面残留物,则建议协调与其他蛋白质和/或小配体; 7重复副本存在于相互作用这条路。

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are propos

WD40域,在真核蛋白质的数量发现,涵盖了包括各种功能适配器/信号转导,mRNA前体细胞骨架组装加工和管理模式;通常包含一个从11月24日生长激素肽的N残留端和西部数据肽在其C端和40残留长,因而得名WD40;介于生长激素和WD一个保守的核心,作为一个稳定的螺旋桨式平台,可以绑定的蛋白可以稳定或可逆,形成了一个螺旋桨式与每个刀片是一个四叶片结构组成若干链反平行的β-片;与数份检测实例假设,形成了聚大结构,每个WD40重复序列形成了前三个一个刀片和绞线的最后在未来的刀片链,最后C -末端WD40重复完成了第一WD40重复叶片结构,创造螺旋桨的封闭环结构,对螺旋桨顶部和底部表面残留的建议,配合和其他蛋白质的相互作用/或小配体; 7重复副本,目前这条路。

Results Basal cell adenocarcinoma of prostate was composed of poorly differentiated solid carcinoma nests with many cellular nuclear mitoses arranged like basal cell carcinoma. Necrosis was in the middle of the carcinoma nest. Local differentiation to squamous cell, transitional cell and gland and structure like adenoid cystic carcinoma were found.

结果:前列腺基底细胞腺癌为分化差的实体癌呈基底细胞癌样排列,核分裂象多,癌巢中央伴坏死,可见局灶性鳞状细胞、移行细胞或腺管分化,也可出现腺样囊性癌样结构。

The fulllength heparanase gene is isolated. The functional heparanase is expressed within COS7 and CHO cells and few heparanse is secreted into medium. The positive CHO cells expressing active heparanase is screened, which will help explore its function and screen its antibody and antagonists from a variety of sources.

本研究分离出人HPA编码基因全序列;在真核细胞内成功表达出有活性的人HPA,发现此酶在COS7和CHO细胞中表达在细胞内,很少分泌到细胞外;筛选出其恒定表达细胞株,为进一步研究HPA结构功能、开发其抗体及抑制剂提供了有力的工具。

The fulllength heparanase gene is isolated. The functional heparanase is expressed within COS7 and CHO cells and few heparanse is secreted into medium. The positive CHO cells expressing active heparanase is screened, which will help explore its function and screen its antibody and antagonists from a variety of sources.

本分离出人HPA编码基因全序列;在真核细胞内成功表达出有活性的人HPA,发现此酶在COS7和CHO细胞中表达在细胞内,很少分泌到细胞外;筛选出其恒定表达细胞株,为进一步研究HPA结构功能、开发其抗体及抑制剂提供了有力的工具。

objectiveto investigate the effects of yuegan capsule on ccl4 intoxicated primary cultured rat hepatocytes.methodshepatocytes injury models were induced by ccl4 in rats in vitro, and treated with yuegan capsule.structure of rat hepatocytes and effect of sdh、acpase、g 6 pase activeties and amount of hepatic glycogen were observed.

目的探讨悦肝胶囊对四氯化碳(ccl4)损伤原代培养大鼠肝细胞的保护作用。方法以ccl4诱导大鼠肝细胞损伤模型,观察悦肝胶囊对肝细胞的琥珀酸脱氢酶、酸性磷酸酶、葡萄糖-6-磷酸酶(g 6 pase)活性和糖原含量以及肝细胞形态结构的影响。

Electron microscopy revealed that large amount of elastic fibers were found under the inner wall of Schlemms canal and in JCT and trabecular meshwork.

电镜下可见Schlemm氏管内壁与其下的细胞外基质结构对合,JCT组织较紧密,无内壁与其下JCT的分离;细胞与细胞及细胞与基质间的连接保持完整。

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