细胞组织学诊断

The recognition of this entity is of great importance to both pathologists and clinicians because atypical cellular neurofibroma is clever at masquerading both histologically and cytologically as a sarcoma therefore , a precise diagnosis of this variant is essential because of the differences in treatment and clinical behavior between benignancy and malignancy .

对於病理医师和临床医师来说，区分出这个纤维神经瘤的变异型非常重要，因为异生细胞纤维神经瘤在组织学上和细胞学上都非常类似肉瘤，因此正确的诊断出这个纤维神经瘤的变异型是必要的，因为临床上对於良性和恶性肿瘤的治疗和肿瘤行为表现是不同的。

Some of the laryngeal MFH were difficult to be differentiated from carcinosarcoma, pleomorphic rhabdomyosarcoma , myxoid liposarcoma ,malignant neurilemmoma and myxoma without immunohistochemical aids .

喉恶性纤维组织细胞瘤常规组织学与癌肉瘤、多形性横纹肌肉瘤、粘液型脂肪肉瘤、恶性神经鞘瘤、粘液瘤有时易混淆，免疫组织化学有助于明确诊断。

Debris necrosis of lymph node is not the specific changes of KD. In the tuberculosis of lymph node,① debris necrosis is obvious, but it tends to be caseous nercrosis;② histiocytes, macrophages and foam cells are hyperplasia in the necrotic area or lymph sinus, moreover, epithelioid cells can be found and they tend to be form granuloma;③ numbers of neutrophils infiltrate in the necrotic area;④ the etiologic assay of acid fast bacterium tuberculosis bacterium is positive;⑤ typical clinical manifestation is insufficient.

淋巴结碎屑性坏死并非KD特有病变，诊断KD需先除外有明显碎屑性坏死的淋巴结结核病，后者主要表现：①碎屑性坏死虽明显，但趋于干酪样坏死；②坏死区内或同时在淋巴窦内，组织细胞、巨噬细胞和泡沫细胞增生，并演变为上皮样细胞和趋于肉芽肿形成；③坏死灶内、外可有数量不等的中性粒细胞浸润；④抗酸杆菌／结核杆菌病原学检测阳性；⑤缺乏KD的典型临床过程。

The face was edematous, and there were some edematous and erythematous plaques with a necrotic center on the legs and arms.

组织学上，在真皮的血管和附属器周围，可见大量表达CD8异形淋巴细胞浸润，诊断CD8+皮肤T细胞淋巴瘤。

Our results demonstrate that (1) the lipogenic tumor markers CDK4 and MDM2 can be used as surrogate immunohistochemical markers for the diagnosis of malignant lipomatous tumors with high sensitivity;(2) approximately 26% of retroperitoneal/thigh UHGPS cases that were positive for PPAR-γ, CDK4, or MDM2 by immunohistochemistry showed characteristic CDK4 and MDM2 gene amplification, suggesting that a subset of UHGPS cases represent DDL despite lacking histologic evidence of lipoblasts.

我们的结果表明：（1）脂肪源性肿瘤标记CDK4和MDM2可以作为诊断恶性脂肪肿瘤的免疫标记物，且敏感性高；（2）腹膜后/大腿UHGPS免疫表达PPAR-γ， CDK4或MDM2的病例中，约有26%例显示特征性的CDK4和MDM2基因扩增，这表明部分UHGPS病例表现为DDL，虽然组织学上找不到脂母细胞。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失