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The percentage of myelocytic circles in AL patients was significantly lower than in normal controls, indicating hemopoietic hypofunction in AL patients.

AL患儿骨髓细胞周期的S期细胞比例明显低于正常对照,说明AL患儿白血病细胞的增殖能力低下。

Methods Granulocyte/macrophage colony stimulating factors and interleukin 4 were used to cultivate DC from peripheral blood of hepatocellular carcinoma patients.Tumor associated antigen extracted from human liver cancer HepG2 cell line was used to activate the DC,which will initiate homogenic T lymphocyte to form cytotoxic T lymphocyte.HepG2 cells were transplanted to the nude mice and were treated with CTL.Expression of PCNA in tumor cells was evaluated.

联合应用粒/巨细胞集落刺激因子及白介素-4(IL-4)直接从肝癌患者外周血中培养出DC;以源于人肝癌细胞系HepG2细胞的肿瘤抗原粗提物刺激DC;DC激活同源的T淋巴细胞产生细胞毒性T淋巴细胞;建立人肝癌细胞系HepG2裸鼠移植瘤模型;CTL治疗人肝癌细胞系HepG2裸鼠移植瘤;检测移植瘤标本肿瘤细胞PCNA表达水平。

Objective: The first aim of this study was to investigate bcr-abl associated T cell receptorVαand Vβgene repertoire by analyzing the restricted usage and clonal expansion of TCRVαand Vβsubfamily T cells from the normal individual peripheral blood induced bybcr-abl peptideso The second aim was to construct the idiotype TCR Vα-PIRES-TCR Vβeukaryotic vector and investigate its expression in vitro. The data will be expected toprovided the methods in development of the leukemia antigen specific cytotoxic Tlymphocyte modified by the specific TCR.

目的:通过分析bcr-abl多肽诱导正常人T细胞克隆性增殖和TCR Vα和TCR Vβ基因选用情况,获得识别bcr-abl多肽的特异性TCR基因,并构建TCR Vα和TCR Vβ双基因表达载体及分析其体外转染细胞和表达特点,从而为研制TCR转基因获得白血病抗原特异T细胞的研究提供实验依据。

Xpression of TGFαand EGFR protein in oocytes, preimplantation embryos and reproductive tracts by immunohistochemy 2.1 Expression of TGFαand EGFR protein in oocytes and preimplantation embryos The results showed that expression of EGFR and TGFαwere in immatured and matured oocytes, cumulus cells, fertilized oocytes and different stage of preimplantation embryos.

GFR和TGFα在未成熟卵母细胞、卵丘细胞和成熟卵母细胞的细胞膜区域均有表达,TGFα在受精卵中的表达量明显增加。

Objective To study the selective toxicity of immunotoxin on T cells and to determine its effect on hematopoietic progenitor cells.

目的 探讨抗T细胞免疫毒素(immunotoxin, IT)体外对脐血T细胞的清除效率及对造血干/祖细胞的影响。

Comparative studies of electroactive components and voltammetric behaviors different between the MCF-7 cell without estrogen and the MCF-7 cell with estrogen showed that the concentration of the guanine and xanthine bases in the cytoplasm decreased, which resulted in the decrease of secretion ability of the MCF-7 cell without estrogen decreased, and these result in the decreasing of the voltammetric response of the cells, impling that the cell vaibility decreases.

结果发现,去激素MCF-7细胞质中的黄嘌呤和鸟嘌呤浓度降低,使细胞分泌黄嘌呤和鸟嘌呤能力降低,导致细胞和细胞质的伏安信号减弱,说明去激素MCF-7细胞的活性下降;研究了标准雌激素雌二醇、环境雌激素壬基酚和双酚A对去激素培养的MCF-7细胞增殖的影响,发现其均存在剂量-效应关系和时间-效应关系,并且雌激素效应由大到小的顺序为:雌二醇>壬基酚>双酚A;同时使用3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide法验证了电化学法评价雌激素效应的可靠性。

Multiplication capacity of CIK cells is far greater than that of LAK cells by tens of times.

CIK细胞增殖能力大大优于LAK细胞,在短期培养后即可达到临床所需要的抗肿瘤效应细胞的数量。

The results suggest that REV viral determination is same in both the group;REV viral antigen could be detected in the bursa of Fabricius, bone marrow, and glandularis venticuli, spleen, thymus, liver, lung, kidney and heart;viruses located maily in the immature lymphotaxis and reticular cell.

REV抗原阳性细胞的分布及形态特征基本相同,阳性细胞主要是正在发育成熟的淋巴细胞和上皮性网状细胞。

The expression of VEGF was observed by using image analysis and the secretion of VEGF by macrophagus was tested by using immunohistochemistry method.

结果:在口腔鳞癌中,VEGF的表达和微血管计数、巨噬细胞计数呈现正相关(P.05);VEGF的表达、巨噬细胞的浸润和肿瘤的淋巴结转移有关(P.05),口腔癌浸润的巨噬细胞中有29%~10%的细胞内有VEGF的表达。

Mechanistically, CYR61 enhanced bmp-2 mRNA and protein expression in time- and dose-dependent manners, and osteoblast migration, proliferation, and differentiation abilities were significantly inhibited by BMP-2 neutralizing antibody.

实验结果发现,将CYR61重组蛋白处理造骨细胞,观察到随著CYR61处理浓度增加,可以促进造骨细胞的增生、移动;随著处理时间的延长可以促使细胞矿物质化。

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We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称;三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起,称之为挽歌体诗人或者史诗诗人,他们被称为诗人,似乎只是因为遵守格律写作,而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。

This is not paper type of business,it's people business,with such huge money involved.

这不是纸上谈兵式的交易,这是人与人的业务,而且涉及金额巨大。