细胞的

A challenge in such a use is expansion and directed seeding in itro, requiring proliferation and surial, and directed migration, respectiely, prior to functional differentiation. The epidermal growth factor receptor is the prototypal growth factor receptor and elicits these responses from a wide ariety of stromal, epithelial, and endothelial cells.

对于这一种细胞的应用所面临的挑战是在功能性分化前在体外的直接种植和扩增、增殖及分化以及导向性迁移等，表皮生长因子受体是一种原型生长因子受体可以在间质细胞、表皮细胞及内皮细胞中引出上述效应。

Results The cells became larger and showed more pseudopodia, having atendency to differentiate, the detection of cell cycle showed a decrease of S stage andan increase of G1 stare, cell proliferation ability in vitro and tumorigenesis ability in nude mice were discounted, the final tumor volume and weight were also decreasedafter knocking down NS gene.

结果NS基因在PC-3细胞中的表达水平下调后，细胞胞膜边缘突起增多，更趋向于分化；S期细胞的百分率降低，G1期的百分率升高；细胞的体外增殖速率明显降低，在裸鼠体内致瘤能力、肿瘤的生长速度及肿瘤的最终体积和重量也明显降低，细胞凋亡增多。

While the tissue spaces surrounding a few blood vessels wasAl and Fg positive,no Al or Fg positive cells were observed.In antemortem injurygroup,diffuse subarachnoid hemorrhage,cerebral edema,swelling or pyknotic neu-rons could be observed.The axons showed irregular swelling and disconnection at1～3h,marked swelling and disconnection at 6h,and retraction ball at 15h whichwas more remarkable at 24h after injury.The space between myelin sheaths andaxons was increased at 3～6h after injury.Tortuous and wavelike myelin sheathswhich adhered on axons incompletely,or even peeled off could be found from 15hto 24h after injury.Perinuclear lysis of Nissl bodies began at 24h after injury.Thenumber of GFAP positive cells in cerebrum and brain-stem increased significantlyfollowed by decrease,and then increased again,but the time courses of the changesin different areas of brain were not same.Al and Fg positive neural cells,mainlysurrounded blood vessels,with diffuse or peripherally distributed positive matter incytoplasm could be observed at 0.5h after injury.The number of Al or Fg positivecells and the intensity of immunoreaction increased with the time of injury.The areaof SYN positivity in medulla oblongata and pons decreased notably 3～6h afterinjury,then return to normal levels and continued to 24h after injury.

生前损伤组，可见广泛蛛网膜下腔出血，脑组织水肿，神经细胞肿胀，晚期神经元固缩；伤后1～3h见部分神经轴突不规则增粗、断裂，伤后6h断端膨大，伤后15h可见收缩球，至伤后24h更为明显；伤后3～6h可见部分神经髓鞘与轴突之间的间隙增宽，伤后15h髓鞘明显曲折，不完全附着在轴突两侧，甚至剥脱，持续到伤后24h；核周尼氏体减少在伤后24h才开始出现；同一部位的GFAP阳性细胞数目随损伤时间发生改变，先增多（最早在伤后0.5h），达到高峰后减少，其后又有增多趋势，但不同部位的GFAP阳性细胞数目增减的时间过程不尽相同，同时，大脑中的GFAP阳性细胞数目也有改变；伤后0.5h，可在脑干组织中见到Al和Fg阳性神经细胞，主要位于血管周围，阳性物在胞浆中呈弥散性分布，但部分细胞的阳性物仅分布于靠近胞膜的胞浆中而呈环状，随损伤时间延长，阳性细胞数目增多，反应强度增加；伤后3～6h，延髓及桥脑中的SYN阳性物面积减少，其后恢复到正常水平，并持续到伤后24h。

About a year after pollination, the generative cell of the four-celled male gametophyte undergoes division, giving rise to two kinds of cells—a sterile cell and a spermatogenous cell.

在授粉后大约一年，四个中生殖细胞-细胞男性的配偶体接受区分，引起细胞的二个类型-一个不毛的细胞和一个 spermatogenous 细胞。

Vein transplantation of human UCB-MSCs has protective effects on splenocyte damages induced by irradiation, can promote proliferation and accelerate repair of splenocytes. The action mechanism is associated with elevating natural killer cell activity, and number of CD4+ and CD8+.

脐血间质干细胞静脉输注对辐射造成的脾细胞损伤有一定保护作用，可促进脾脏细胞的分裂增殖，加速脾脏细胞的修复，其作用机制可能与提高NK细胞活性和CD4+、CD8+数量有关。

Objective: To explore the mechanisms resulting in the recurrence of urethral scar which make urethral strictures difficult to be cured, a series experiments were conducted to find potential effective factors involved in urethral scar formation and degradation, including the studies of extracellular matrix component of urethral stricture scar, the characteristics of urethral scar fibroblast, and the effects of urine on urethral fibroblast in vitro, as well as the studies to compare the difference of collagenase activity, type Ⅰ collagen and tissue inhibitor of metalloproteinase-1 (TIMP-1) in the tissues and cultured fibroblasts from normal urethra and strictured urethra respectively, and the studies to investigate the effect of antisense TIMP-1 oligodeoxyonucleotide on cell proliferation and collagenase activity of urethral scar fibroblast.

中文题名尿道瘢痕基础研究副题名胶原酶活性，TIMP-1的表达及其反义基因治疗外文题名 Experimental study on urethral scar-activity of collagenase，expression of TIMP-1，and antisense TIMP-1 gene transfection of urethral scar fibroblast 论文作者黄翔导师杨宇如教授学科专业外科学研究领域\研究方向学位级别博士学位授予单位四川大学学位授予日期2002 论文页码总数104页关键词尿道手术瘢痕胶原酶成纤维细胞尿道瘢痕馆藏号BSLW /2003 /R699 /12 目的：研究尿道瘢痕的细胞外基质的组成，尿道瘢痕成纤维细胞的生物学特性以及尿液对其生长的影响；比较胶原酶活性，金属蛋白酶组织抑制因子-1（TIMP-1）以及Ⅰ型胶原含量在尿道瘢痕和正常尿道组织及体外培养的成纤维细胞中的差异；研究反义TIMP-1寡核苷酸对尿道瘢痕成纤维细胞增殖以及胶原酶活性的影响。

In particular, if they could enter the cell, the process of internalization, their localization in intracellular compartments, and their succedent effects on the cellular functions, the current findings for these aspects are summarized in this paper.

尤其是这类纳米颗粒是否能够进入细胞，如何进入细胞，在细胞内的定位，以及对细胞的生物学功能有何影响，本文对这些问题，从不同的方面进行了综述和探讨。

The cytoplasm of the tapetum cells of Zhenshan 97A deposited a few Ca(superscript 2+) precipitates at the pollen mother cell stage. At the meiosis stage, there were many large Ca(superscript 2+) precipitates at the inner longitudinal cell wall; there were a layer Ca(superscript 2+) precipitates around the tapetal cells.

珍汕97A绒毡层细胞从花粉母细胞时期开始，细胞质内有少量颗粒状的Ca(上标 2+)沉淀；减数分裂时期，绒毡层细胞的内切向壁表面有大量大颗粒的Ca(上标 2+)沉淀；单核花粉时期绒毡层细胞周围集聚一层Ca(上标 2+)沉淀。

It is concluded that AD5/F35 vector infection has difinite selectivity to hematologic malignant cells of varions origin,the infection ability of AD5/F35 vector to cells of myeloid origin is stronger than that to cells of B cell origin,the cytotoxicity of AD5/F35 vector to infective targer cells is small.

AD5/F35载体对不同来源的血液恶性细胞的感染具有一定的选择性，对髓系来源细胞感染能力强，对B系来源细胞有一定感染能力，而且对感染靶细胞毒性小。

Conclusions1、E_2 may induce the apoptosis and Fas,FasL expressions of Jurkat cell,its effect positively related to the dose and treating time of E_2.2、There is intrinsic co-expression of ERαand ERβon Jurkat cell,which can be upregulated by E_2,positively related to E_2 doses.3、E_2 may act as an apoptosis inducer of Jurkat cell via ERβ.4、E_2 can promote the transcriptive activity of NF-κB in Jurkat cell.The increased NF-κB activity may lead to increased apoptosis of Jurkat cell.

结论1、E_2可增加Jurkat细胞的凋亡，并增加Fas、FasL的蛋白表达，且其作用与E_2的剂量和处理时间呈正相关。2、Jurkat细胞上存在ERα、ERβ的表达，且E_2可上调这两种受体的表达，E_2剂量越大，ER表达量越高。3、E_2可能通过ERβ发挥其促进Jurkat细胞凋亡的作用。4、E_2能增加Jurkat细胞中NF-κB的转录活性，Jurkat细胞中NF-κB活性增加有促进凋亡的作用。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。