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细胞滋养层

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Embryonic germ layer on ventral aspect of the bilaminar disk that gives rise to endoderm.

双层椎间盘腹侧形成滋养层细胞的三个胚层组织引起的内胚层。

BACKGROUND: The natural killer cells at the site of placentation express killer-cell immunoglobulin-like receptors that can bind to human leukocyte antigen-C molecules on trophoblast cells.

背景:自然杀伤细胞在胎盘形成时表达伤细胞免疫球蛋白样受体,它可以在滋养层细胞上与人白细胞抗原-C分子结合。

Results: IL-8 protein was located in the epithelium of viii. The expression of IL-8 was significantly increased in RSA group than that in the control group. Positive IL-8 cells was shown in decidua of RSA group, and its IL-8 level was higher than that in the control group. By hematoxylin-eosin staining. trophoblastic layer was found to get thinner, cells of trophoblastic layer denatured or necrotized, and turned acidophily, and the fibration of villous axis increased in RSA; decidual cells lost connection, a part of decidual cells appeared cytoclasis and turned more acidophilic, and nuclei disappeared in RSA.

结果:在绒毛组织中,IL-8蛋白定位于绒毛上皮细胞的细胞质内,且病例组的表达明显高于对照组;在蜕膜组织中;病例组蜕膜细胞的胞质内可见IL-8蛋白表达,且高于对照组;H-E染色可见病例组绒毛组织的滋养层变薄,细胞变性甚至坏死、嗜酸性增强,绒毛中轴纤维化程度增强;蜕膜组织中蜕膜细胞失去细胞间连接,部分蜕膜细胞解体、核消失。

LMWH might regulate cytotrophoblast invasiveness in vitro by influencing the expression of MMP-2 and TIMP-2 in cytotrophoblastic cells.

低分子量肝素可能直接通过影响绒毛滋养层细胞 MMP-2、TIMP-2的表达进而影响绒毛滋养层细胞的侵袭能力。

The results from flow cytometry assay showed that the low concentrations of LIF had the ability to shift cytotrophoblast differentiation towards a syncytial pathway, while the high concentrations of LIF towards a invasive pathway.

细胞流式仪结果表明低浓度的LIF可促进绒毛合胞体滋养层的分化,高浓度的LIF可促进绒毛外侵入性滋养层细胞的分化。

Results The syncytiotrophoblast,cytotrophoblast and stromal cells were all appeared DHEA immunoreactivity. The immunoreactivematerial was distributed in cytoplasm with immunonegative nucleus.

结果 人胎盘两层滋养层细胞和基质细胞均呈DHEA免疫反应性,反应物质分布于胞质,胞核无免疫反应。

The HBsAg was located in the intervillous space (21 placentas) and...

HBsAg主要分布于蜕膜血管内皮细胞(18例)、蜕膜细胞(21例)、滋养层细胞(8例)、绒毛间质细胞(8例)和绒毛血管内皮细胞(5例)的胞浆和绒毛间隙(21例)中。

HBV transplacental transmission route may be realized by cell to cell transfer in placenta, which means that HBVs in maternal blood and/or intervillous space infect DCEC and/or DC and/or TC, then transmit to VMC, then to VCEC, and finally to fetus.

HBV经胎盘感染胎儿的路径可能是通过胎盘细胞至细胞的传递而实现的。即母血和/或绒毛间隙HBV→蜕膜毛细胞管内皮细胞和/或蜕膜细胞和/或滋养层细胞→绒毛间质细胞→绒毛毛细血管内皮细胞→胎儿。

It was expressed on trophoblastic cell, interstitial cell and endothelium cell of interstitial blood vessels of villi.

结果 ①所有的标本绒毛滋养层细胞、绒毛间质细胞、毛细血管内皮细胞都有HAV的存在。

Furthermore, preliminary work also performed to examine whether PI3K/AKT signal transduction pathway was activated in the process of refractory leukemia development. Materials and methods An immortalized human bone marrow stromal cell line, HS-5, was introduced to establish a bi-phase culture system for the cultivation of B-lineage precursor leukemia cells. ELISA and RT-PCR were used to investigate the expression of VEGF and its receptors in the leukemia cell lines and primary childhood leukemia cells in different treated groups. Flow cytometory method and immunofluorescent staining were employed to examine the apoptosis signals both in the VP16 treated and untreated leukemia cells. Western blot was utilized to explore the PI3K/AKT activated status in the drug induced or uninduced leukemia cells and lymphocytes from healthy donors.

材料和方法使用来源于人类骨髓基质细胞的细胞株HS-5作为滋养层细胞进行急性淋巴细胞性白血病细胞的体外培养,通过细胞生物学和免疫学方法评估培养体系并鉴定出难治性白血病细胞克隆;以ELISA和RT-PCR方法检测急性白血病细胞株和患儿白血病细胞VEGF及其受体的表达,了解不同治疗阶段VEGF及其受体的表达状况,并结合临床指标进行分析,明确VEGF及其受体在白血病发生过程中的作用;流式细胞仪和免疫荧光染色法对正常健康儿童、初发白血病患儿、复发白血病患儿及缓解后患儿进行凋亡因子检测和分析,初步阐明难治性白血病抗凋亡形成的原因;蛋白印记分析检测PI3K/AKT信号传导通路在健康儿童、初发白血病和复发白血病患儿的表达,初步了解难治性白血病形成的分子生物学机制。

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